scholarly journals Gambaran Kejadian Postoperative Nausea and Vomiting (PONV) pada Pasien Pasca Tindakan Dilatasi Kuretase dengan Anestesi Umum di RSIA B pada Tahun 2019

2021 ◽  
Vol 2 (1) ◽  
pp. 10
Author(s):  
Resiana Karnina ◽  
Mayinda Nabilla Ismah
Keyword(s):  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
American Society ◽  
American Society Of Anesthesiologists

Latar Belakang: Anestesi umum merupakan salah satu jenis anestesi yang banyak digunakan untuk tindakan dilatasi dan kuretase. Meskipun demikian, anestesi umum memiliki komplikasi salah satunya yaitu kejadian Postoperative Nausea and Vomiting (PONV). Tujuan: Mengetahui gambaran kejadian Postoperative Nausea and Vomiting (PONV) pada pasien pasca tindakan dilatasi dan kuretase menggunakan anestesi umum di RSIA B pada tahun 2019. Metode: Desain penelitian ini adalah penelitian deskriptif observasional, data diambil dari catatan rekam medis pasien pasca tindakan dilatasi dan kuretase dengan anestesi umum di RSIA B. Sampel diambil dengan metode total sampling sebanyak 139 sampel. Analisa data menggunakan SPSS 26.0 for Windows. Hasil: Dari 139 pasien, angka kejadian Postoperative Nausea and Vomiting (PONV) adalah 16 kasus (11.5%). PONV dengan anestesi umum paling banyak terjadi pada rentang usia 29 – 34 tahun (14%) dan pasien dengan status American Society of Anesthesiologists (ASA) I (13%). Proporsi pasien PONV berdasarkan jenis obat anestesi yaitu pada jenis obat anestesi intravena sebanyak 16 kasus (11.5%). Simpulan: Kejadian Postoperative Nausea and Vomiting (PONV) cukup tinggi, terutama pada rentang usia 29 – 34, status ASA I dan jenis obat anestesi intravena.

scholarly journals Dexmedetomidine use during epiduroscopy reduces fentanyl use and postoperative nausea and vomiting: A single-center retrospective study

2018 ◽  
Vol 6 ◽  
pp. 205031211875680 ◽  
Author(s):  
Takashi Suzuki ◽  
Ryota Inokuchi ◽  
Kazuo Hanaoka ◽  
Machi Suka ◽  
Hiroyuki Yanagisawa
Keyword(s):  
Retrospective Study ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Anesthesia Care ◽  
Low Back ◽  
Monitored Anesthesia Care ◽  
History Of ◽  
American Society ◽  
American Society Of Anesthesiologists

Objectives: Minimally invasive epiduroscopy has recently been reported as an effective treatment procedure for chronic and intractable low back pain. However, no study has determined safe anesthetics for monitored anesthesia care during epiduroscopy. We aimed to compare and evaluate conventional monitored anesthesia care drugs with dexmedetomidine. Methods: A retrospective study including all patients who underwent epiduroscopy at the JR Tokyo General Hospital from April 2011 to March 2016 was designed. The epiduroscopy procedures were performed under anesthesia with dexmedetomidine plus fentanyl (dexmedetomidine group) or droperidol plus fentanyl (neuroleptanalgesia group). Patients who received analgesics other than fentanyl, another analgesic combined with fentanyl, any sedative other than dexmedetomidine or droperidol, or who had incomplete data were excluded. We compared (1) the type and dose of medication during the epiduroscopy and (2) the incidence of postoperative nausea and vomiting. Results: We identified 45 patients (31 and 14 in the dexmedetomidine and neuroleptanalgesia groups, respectively) with a mean age of 69.0 years. The two groups had comparable characteristics, such as age, sex, body mass index, the American Society of Anesthesiologists Physical Status, analgesics used in the clinic, comorbidities, history of smoking, and the duration of anesthesia. The dexmedetomidine group received a significantly lower fentanyl dose during surgery (126 ± 14 vs 193 ± 21 µg, mean ± standard deviation, p = 0.014) and exhibited a significantly lower incidence of postoperative nausea and vomiting (1 vs 3, p = 0.047) than the neuroleptanalgesia group. Conclusion: This study involved elderly patients, and the use of dexmedetomidine in monitored anesthesia care during epiduroscopy procedures in these patients may reduce the required fentanyl dose during surgery and the incidence of postoperative nausea and vomiting. This strategy may help prevent respiratory depression and aspiration.

scholarly journals Comparative Study of Ondansetron Versus Dexamethasone in the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy Under General Anesthesia

2021 ◽  
Vol 4 (1) ◽  
pp. 81-84
Author(s):  
Sundar Prasad Hyoju
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
General Anesthesia ◽  
Postoperative Nausea ◽  
Vital Signs ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Controlled Study ◽  
Double Blind ◽  
American Society ◽  
American Society Of Anesthesiologists

Introduction: Postoperative nausea and vomiting (PONV) have been termed as the “big little problem” for anesthesiology during laparoscopic surgery. Pain and postoperative nausea and vomiting are the most common causes of morbidity after anesthesia and surgery. We aimed to evaluate the effects of Ondansetron and Dexamethasone in preventing postoperative nausea and vomiting following laparoscopic cholecystectomy, as well as to note any pharmacological side effects that occurred after their usage. Methods: In this prospective, randomized, double blind controlled study, trial was done after approval from the IRB and trail registry, 60 female patients of American Society of Anesthesiologists physical status I and II, aged 18 to 65 years, weighing 50-60 kg, and standing 150 to 160 cm, were given institutional ethical committee clearance and written informed consent before undergoing laparoscopic cholecystectomy (duration 90 minutes) under general anesthesia. Patients arriving in the operating room were sorted into two groups of 30 patients each. All patients were monitored after surgery, documenting vital signs and any difficulties that arose. For the first 12 hours after surgery, all bouts of PONV (nausea, vomiting, and retching) were documented. Each patient's data was gathered and tallied. Results: The patients in the study group were similar in age, weight, height, ASA status, and operation duration (p 0.05), and there was no significant statistical difference between the data gathered throughout the study Conclusions: Ondansetron is just as effective as Dexamethasone at lowering nausea and vomiting after laparoscopic cholecystectomy, and it comes with less adverse effects.

Low incidence of postoperative nausea, vomiting, regurgitation, and aspiration pneumonia in geriatric dogs receiving maropitant, famotidine, and fentanyl as part of an anesthesia protocol

2021 ◽  
Vol 260 (S1) ◽  
pp. S46-S51
Author(s):  
Ashley L. Moyer ◽  
Talon S. McKee ◽  
Philip J. Bergman ◽  
Arathi Vinayak
Keyword(s):  
Risk Factors ◽  
Aspiration Pneumonia ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Asa Score ◽  
Surgery Patient ◽  
Potential Risk Factors ◽  
Low Incidence ◽  
American Society ◽  
American Society Of Anesthesiologists

Abstract OBJECTIVE To determine the incidence of and potential risk factors for postoperative regurgitation and vomiting (PORV), postoperative nausea and vomiting (PONV), and aspiration pneumonia in geriatric dogs using premedication with maropitant and famotidine, intraoperative fentanyl, and postoperative fentanyl as part of an anesthetic protocol. ANIMALS 105 client-owned geriatric dogs that underwent general anesthesia for a major surgical procedure between January 2019 and March 2020. PROCEDURES Medical records were reviewed to collect data on signalment, historical gastrointestinal signs, American Society of Anesthesiologists (ASA) score, indication for surgery, duration of anesthesia and surgery, patient position during surgery, mode of ventilation, and perioperative administration of maropitant, famotidine, anticholinergics, opioids, colloidal support, NSAID, corticosteroids, and appetite stimulants. The incidence of postoperative regurgitation, vomiting, nausea, and aspiration pneumonia was calculated, and variables were each analyzed for their association with these outcomes. RESULTS 2 of 105 (1.9%) dogs regurgitated, 1 of 105 (1.0%) dogs developed aspiration pneumonia, 4 of 105 (3.8%) dogs exhibited nausea, and no dogs vomited. Identified possible risk factors included older age (≥ 13 years old) for postoperative regurgitation, regurgitation for postoperative aspiration pneumonia, and high ASA score (≥ 4) for both regurgitation and aspiration pneumonia. CONCLUSIONS AND CLINICAL RELEVANCE The use of an antiemetic protocol including maropitant, famotidine, and fentanyl in geriatric dogs resulted in very low incidences of PORV, PONV, and aspiration pneumonia. Future prospective studies are warranted to further evaluate and mitigate postoperative risks.

Determination of Plasma Concentrations of Propofol Associated with 50% Reduction in Postoperative Nausea 

1997 ◽  
Vol 87 (4) ◽  
pp. 779-784 ◽  
Author(s):  
T. J. Gan ◽  
P. S. A. Glass ◽  
S. T. Howell ◽  
A. T. Canada ◽  
A. P. Grant ◽  
...  
Keyword(s):  
Plasma Concentration ◽  
Postoperative Nausea ◽  
Plasma Concentrations ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Computer Assisted ◽  
Rating Score ◽  
Arterial Blood ◽  
American Society ◽  
Postanesthetic Care Unit

Background Subhypnotic doses of propofol possess direct antiemetic properties. The authors sought to determine the plasma concentration of propofol needed to effectively manage postoperative nausea and vomiting. Methods Patients aged 18-70 yr who were classified as American Society of Anesthesiologists physical status 1 or 2 and had surgery during general anesthesia were approached for the study. Only patients who had nausea (verbal rating score > 5 on a 0- to 10-point scale), retching, or vomiting in the postanesthetic care unit participated. Propofol was administered to these patients to achieve target plasma concentrations of 100, 200, 400, and 800 ng/ml using a computer-assisted continuous infusion device. Target concentrations were increased every 15 min until patients described at least a 50% reduction in symptoms on the verbal rating score. An arterial blood sample was obtained at each step. The measured plasma propofol concentrations were used to analyze data. Blood pressure, heart and respiratory rates, arterial blood saturation, sedation score, and overall satisfaction with treatment were recorded. Results Of the 89 patients who consented to the study, 15 patients met entry criteria and were enrolled. Five of these patients also had retching or vomiting when they entered the study. Fourteen patients responded successfully to treatment. One patient did not achieve the required response at plasma concentrations of 830 ng/ml. Hence the success rate for the treatment of postoperative nausea and vomiting was 93%. Among patients who responded, the median plasma concentration associated with an antiemetic response was 343 ng/ml. There was no difference in sedation scores from baseline and no episodes of desaturation. Hemodynamic parameters were stable during the study. Conclusions Propofol is generally efficacious in treating postoperative nausea and vomiting at plasma concentrations that do not produce increased sedation. Simulations indicate that to achieve antiemetic plasma propofol concentrations of 343 ng/ml, a bolus dose of 10 mg followed by an infusion of approximately 10 microg x kg(-1) x min(-1) are necessary.

scholarly journals Study of efficacy of combination of dexamethasone and ondansetron versus ondansetron alone using SAMBA guidelines for postoperative nausea and vomiting in laparoscopic cholecystectomy.

2020 ◽  
Vol 27 (09) ◽  
pp. 1839-1844
Author(s):  
Ali Arslan Munir ◽  
Abeera Zareen ◽  
Sumbal Rana
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Memory Loss ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Military Hospital ◽  
Significance Level ◽  
American Society ◽  
Group B ◽  
Post Operative Nausea ◽  
American Society Of Anesthesiologists

Objectives: Comparing the effectiveness of combining ondansetron and dexamethasone vs ondansetron unaided in amounts suggested by SAMBA strategies for stoppage of post-operative nausea and vomiting in laparoscopic cholecystectomy patients. Study Design: Randomized Control trial. Setting: Department of Anaesthesia, Combined Military Hospital, Rawalpindi. Period: Six months (April 2015–October 2015). Material & Methods: A sum of 160 patients were experimented by taking 80 in every group. Group A: of ondansetron. Group B: ondansetron plus dexamethasone. Significance level: 5% Test power: 80% Proportion of the projected population A is 72%1. Foreseen population percentage B is 88%1. Besides successive non-probability specimen system was taken for sample gathering. Patients who were selected were American society of anesthesiologists 1 & 2 while ones with struggle in communiqué e.g. psychologic issues, memory loss, loss of speech etc, pregnant and menstruating ladies3, known of PONV, motion disease, ear problems and vertigo, on long term steroid use3, anguished from diabetes mellitus, hiatal hernia were excluded. The frequency of side effects were duly scribed down and doses of drugs wrote down. Rescue anti vomiting was secondhand for ones of PONV. Results: We deduced that mixture of ondansetron & dexamethasone was effectual in averting post-operative nausea & vomiting equated to Ondansetron unaided. Conclusion: There is variance in incidence of PONV in mutual clusters with combination remedy of ondansetron plus dexamethasone being safer as equated to Ondansetron unaided.

Australian perspective on Fourth Consensus Guidelines for the management of postoperative nausea and vomiting

2021 ◽  
pp. 0310057X2110305
Author(s):  
Claudia A von Peltz ◽  
Celine Baber ◽  
Suzi LH Nou
Keyword(s):  
Postoperative Nausea ◽  
Enhanced Recovery ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Consensus Guidelines ◽  
Australian Society ◽  
American Society

This is a summary document that provides an Australian perspective on the Fourth Consensus Guidelines for the management of postoperative nausea and vomiting. The Australian Society of Anaesthetists has endorsed the Fourth Consensus Guidelines for the management of postoperative nausea and vomiting and has written this document with permission from the authors and the American Society for Enhanced Recovery to provide an Australia-specific summary.

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