scholarly journals Study on the Formation of Osteoclasts by Prostaglandin E_2 (PGE_2) and Interleukin 1 (IL-1) in Mouse Bone Marrow Culture

1993 ◽  
Vol 47 (5) ◽  
pp. 499-509
Author(s):  
Yoshiya Tanaka
Blood ◽  
1987 ◽  
Vol 69 (2) ◽  
pp. 682-691 ◽  
Author(s):  
D Rennick ◽  
G Yang ◽  
L Gemmell ◽  
F Lee

A stromal cell line, GY30, was cloned from mouse bone marrow adherent cell layers. In culture, GY30 cells sustain the production of granulocyte-macrophage progenitor cells (GM-CFU) but fail to support the survival of pluripotential stem cells (CFU-S). GY30 cells secrete two growth factor activities distinct from interleukin-3 (IL-3), IL-2, and macrophage colony-stimulating factor (M-CSF) but functionally similar to GM-CSF and G-CSF. The production of both CSFs is increased 70- to 200-fold by treating GY30 cells with lipopolysaccharide or IL-1. RNA blot analysis reveals the presence of GM-CSF and G-CSF transcripts and demonstrates that IL-1 regulates the production of both factors at the mRNA level. Further, these studies show that the GM-CSF secreted by GY30 cells is structurally similar to the GM-CSF produced by activated T cells.


2012 ◽  
Vol 4 (10) ◽  
pp. 1215 ◽  
Author(s):  
Masayoshi Yamaguchi ◽  
M. Neale Weitzmann ◽  
Clifton A. Baile ◽  
Tomiyasu Murata

1984 ◽  
Vol 2 (6) ◽  
pp. 394-407 ◽  
Author(s):  
Ursula Reincke ◽  
Markus Loeffler ◽  
H. Erich Wichmann ◽  
Bettina Harrison

1984 ◽  
Vol 2 (6) ◽  
pp. 408-424 ◽  
Author(s):  
H. Erich Wichmann ◽  
Markus Loeffler ◽  
Ursula Reincke

Bone ◽  
1994 ◽  
Vol 15 (2) ◽  
pp. 238
Author(s):  
TJ Allain ◽  
AM Flanagan ◽  
AM McGregor ◽  
TJ Chambers

2001 ◽  
Vol 16 (6) ◽  
pp. 769 ◽  
Author(s):  
Hoyeon Chung ◽  
Young Soon Kang ◽  
Chang Sun Hwang ◽  
In Kul Moon ◽  
Chang Hoon Yim ◽  
...  

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