scholarly journals Atypical sonographic presentation of diabetic mastopathy: A case report and literature review

2021 ◽  
Vol 11 ◽  
pp. 60
Author(s):  
Erika Wood ◽  
Pamela Propeck
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Disease Process ◽  
Rare Condition ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Diagnostic Challenge ◽  
Core Needle ◽  
Palpable Breast

Diabetic fibrous mastopathy (DFM) is a relatively rare condition that most often occurs in insulin-dependent diabetics with a characteristic hypoechoic appearance on ultrasound (US). DFM frequently poses a diagnostic challenge in radiology due to malignant imaging similarities, and core needle biopsy is often required. If DFM is in the differential, fine-needle aspiration should not be considered as it will likely be non-diagnostic due to insufficient sampling and excisional biopsy should be avoided as it may worsen the disease process. Therefore, high clinical suspicion of DFM is important for diagnostic intervention consideration. We report the case of a 57-year-old who presented with a firm breast lump which on mammography was seen as a new 5.8 by 5.3 cm global asymmetry. US was performed and a diffuse area of increased echogenicity without posterior shadowing was identified. Given the appearance and patient history, DFM was considered unlikely. However, core needle biopsy revealed diabetic lymphocytic mastopathy consistent with DFM. Even though DFM is uncommon and has been reported to have a specific US appearance, it should be included in the differential for a palpable breast lump in any diabetic patient regardless of glucose control or atypical imaging findings.

scholarly journals A comparative clinicopathological study between ultrasonography, mammography, fine needle aspiration cytology and core needle biopsy of breast lump

2020 ◽  
Vol 7 (7) ◽  
pp. 2325
Author(s):  
Arnab Mandal ◽  
Pradipta Jana ◽  
Sabyasachi Bakshi ◽  
Ram Krishna Mandal
Keyword(s):  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Background: Early presentation and prompt diagnosis is the essential key in treatment of different variety of neoplastic as well as non-neoplastic breast disease. In this study usefulness of high-resolution ultrasonography (HRUSG), mammography, fine needle aspiration cytology (FNAC) and core needle biopsy in correlation with histopathological pattern, was assessed.Methods: After matching the criteria, 212 cases, were taken for this prospective, single center, observational study.Results: Out of 212 cases, 163 (76.88%) were benign lesions, 49 (23.11%) were malignant and 1 (0.47%) were of inflammatory pathology. Benign to malignant breast disease ratio was 3.3:1. Out of 49 malignant cases, 45 (91.83%) were ductal cell carcinoma and 4 (8.16%) was apocrine carcinoma. Maximum numbers of cancer patients were found in the 51-60-year age groups. The sensitivity, specificity, positive predictive value and negative predictive value of mammography in detecting carcinoma breast were 87.76%, 64.71%, 87.76% and 64.71% respectively. The sensitivity, specificity, positive predictive value and negative predictive value of HRUSG in detecting carcinoma breast were 85.71%, 90.18%, 72.41% and 95.45% respectively. Among benign lesions, 47 (28.83%) were diagnosed by mammography and 147 (90.18%) were diagnosed by HRUSG. When these modalities were combined, >95% of the lesions was diagnosed accurately.Conclusions: Ultra sound used liberally as an adjunct to mammography, increase the cancer detection rate. Core needle biopsy is found more accurate but FNAC have limited value in evaluation of benign breast lump. This study also proves that preoperative categorization of breast lesions is utmost important for management of the patient and this will help to avoid unnecessary surgical treatment.

scholarly journals ADVANTAGE OF CORE NEEDLE BIOPSY OVER FINE NEEDLE ASPIRATION CYTOLOGY IN PALPABLE BREAST LUMPS

2016 ◽  
Vol 5 (67) ◽  
pp. 4759-4763
Author(s):  
Guddi Rani Singh ◽  
Manoj Kumar Rai ◽  
Reecha Singh ◽  
Bipin Kumar ◽  
Vijayanand Choudhary ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

scholarly journals Comparison of fine needle aspiration cytology and core needle biopsy findings with excisional biopsy in breast malignancy

2019 ◽  
Vol 9 (2) ◽  
pp. 1564-1570
Author(s):  
Uma Bhatta ◽  
Shovana Karki ◽  
Gita Sayami ◽  
Dosti Regmi
Keyword(s):  
Fine Needle Aspiration ◽  
Core Needle Biopsy ◽  
Fine Needle Aspiration Cytology ◽  
Needle Biopsy ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Fine needle aspiration cytology and core needle biopsy are reliable procedures for breast cancer detection. Core needle biopsy is an established alternative to surgical biopsy for diagnosis and prognostication. However, there may be a concern that core needle biopsy may be less reliable than excisional biopsy. The aim of this study was to compare the cytological/core needle biopsy finding with excisional histopathological diagnosis and determine their hormonal status. Materials and Methods: A prospective study of 65 patients was conducted after obtaining a detailed clinical data. The comparison of the fine needle aspiration cytology/core needle biopsy finding with excisional histopathological diagnosis of breast malignancy was carried out after data analysis. Their ER, PR and HER-2/neu status was also studied in available cases. Results: Out of the 65 cases of breast malignancy, 69.2% of cases had undergone fine needle aspiration, 60% cases core needle biopsy and 93.8% cases excisional biopsy. The most common carcinoma was invasive carcinoma of no special type. The diagnostic accuracy of fine needle aspiration and core needle biopsy was almost equal, however, core needle biopsy could assess the histological typing and biomarker status. The hormonal status was assessed in 69.23% cases, among them 35.6% cases were triple negative carcinomas. Conclusions: Core needle biopsy was superior to fine needle aspiration cytology in the diagnosis of breast lesions in terms of diagnostic accuracy. Thus, our result provides valuable prognostic information to guide the decision-making process for the treatment of a patient with invasive carcinoma.

scholarly journals Diagnostic Challenge of a Deep Minor Salivary Gland Neoplasm

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Vivian P. Wagner ◽  
Manoela D. Martins ◽  
Bruna Genari ◽  
Fernando B. do Amaral ◽  
Antônio C. Maciel ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Single Case ◽  
Minor Salivary Gland ◽  
Needle Aspiration ◽  
Salivary Gland Neoplasm ◽  
Diagnostic Challenge ◽  
Core Needle ◽  
Minor Salivary Gland Tumors

Core needle biopsy represents a safe and cheap alternative diagnostic method to open biopsy and fine-needle aspiration cytology in head and neck tumors. There is little evidence in the literature about the use of core needle biopsy in minor salivary gland lesions. This single case report presents a 60-year-old woman with a painless swelling in the soft palate, breathing and swallowing difficulties, and a feeling of suffocation. Two open biopsies had inconclusive diagnosis and the lesion could only be assessed and diagnosed as pleomorphic adenoma through core needle biopsy. Recognizing the correct indication of core needle biopsy can benefit both health professionals and patients; thus, it is important to consider the possibility of performing this method to diagnose minor salivary gland tumors.

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