scholarly journals Not Every Fat-Containing Lesion on Mammogram is a Benign Finding: Case Report and Review of Breast Malignant Phyllodes Tumor with Heterologous Liposarcomatous Differentiation

2019 ◽  
Vol 9 ◽  
pp. 10
Author(s):  
Neetu Soni ◽  
Nour T Aly ◽  
Aditi Vidholia ◽  
Fabiana Policeni
Keyword(s):  
Case Report ◽  
Phyllodes Tumor ◽  
Imaging Findings ◽  
Malignant Phyllodes Tumor ◽  
Phyllodes Tumors ◽  
Epithelial Component ◽  
Sarcomatous Transformation ◽  
Increased Risk ◽  
Stromal Component ◽  
Proven Case

Phyllodes tumors (PTs) are a rare fibroepithelial tumor of the breast. Histopathological confirmation of stromal and epithelial component is required for making the diagnosis of PT, and stromal component carries an increased risk of sarcomatous transformation. We present imaging findings of a histologically proven case of malignant PT with heterologous liposarcomatous transformation of the breast.

scholarly journals Recurrent Giant Malignant Phyllodes Tumor of the Breast

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Erik Kudela ◽  
Karol Kajo ◽  
Erik Kozubik ◽  
Tomas Rokos ◽  
Terezia Pribulova ◽  
...  
Keyword(s):  
Case Report ◽  
Latissimus Dorsi ◽  
Multiorgan Failure ◽  
Phyllodes Tumor ◽  
Latissimus Dorsi Muscle ◽  
Malignant Phyllodes Tumor ◽  
Dorsi Muscle ◽  
Increased Risk ◽  
Stromal Component ◽  
Cutaneous Flap

Phyllodes tumors (PTs) are rare fibroepithelial neoplasms of the breast. They have a proliferating stromal component that can be graded as benign, borderline, and malignant. In addition, they are associated with an increased risk of local recurrence and distant metastasis. The authors hereby present a case report of a 34-year-old woman with recurrent malignant PT with an increasing aggressiveness. There were two recurrences of giant tumors that consumed the entire right breast, which developed over a three-year period. The final surgical treatment was a total extirpation of the tumor with subsequent plastic reconstruction using a cutaneous flap from the region of the latissimus dorsi muscle. The patient died three months after the last recurrence due to multiorgan failure.

scholarly journals Malignant Phyllodes Tumor of the Breast with Metastasis to the Pancreas: A Case Report and Review of Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
R. A. Amir ◽  
Rola S. Rabah ◽  
S. S. Sheikh
Keyword(s):  
Case Report ◽  
Breast Neoplasms ◽  
Distant Metastasis ◽  
Case Reports ◽  
Phyllodes Tumor ◽  
Pancreatic Metastasis ◽  
Rare Tumor ◽  
Review Of Literature ◽  
Malignant Phyllodes Tumor ◽  
Phyllodes Tumors

Phyllodes tumor (PT) is a rare tumor of the breast accounting for approximately 1% of all breast neoplasms. In 1838, J. Muller coined the term “cystosarcoma phyllodes” based on the leaf-like projections of the tumor extending into the cystic spaces and sarcomatous stromal growth. However, seeing as up to 70% of phyllodes tumors are benign, “cystosarcoma” was removed, and the tumor is now recognized simply as phyllodes tumor. It is mainly seen in females between the ages of 35 and 55. Although most phyllodes tumors are benign, malignant cases do uncommonly occur, 22% of which have distant metastasis typically to the lungs and bones. Rarely, this tumor metastasizes to other locations. Herein, we report a case of malignant phyllodes tumor with metastasis to the pancreas. According to our knowledge, only 3 case reports of pancreatic metastasis from malignant phyllodes tumor have been reported in literature thus far. We aim to increase awareness among physicians of this rare metastasic potential of the uncommonly encountered malignant phyllodes tumor.

Malignant phyllodes tumor composed almost exclusively of a fibrosarcomatous component: a case report and review of malignant phyllodes tumors with metastases

Breast Cancer ◽  
2009 ◽  
Vol 17 (3) ◽  
pp. 218-224 ◽  
Author(s):  
Satomi Suzuki-Uematsu ◽  
Kazuko Shiraishi ◽  
Taro Ito ◽  
Naoki Adachi ◽  
Yoshihisa Inage ◽  
...  
Keyword(s):  
Case Report ◽  
Phyllodes Tumor ◽  
Malignant Phyllodes Tumor ◽  
Phyllodes Tumors

scholarly journals Malignant Phyllodes Tumor with Chondrosarcomatous Differentiation: Radiological-Pathological Correlation

2014 ◽  
Vol 4 ◽  
pp. 52 ◽  
Author(s):  
Kathyayini Paidipati Gopalkishna Murthy ◽  
Ranjani Padmanabhan Chakravarthy
Keyword(s):  
Chest Wall ◽  
Phyllodes Tumor ◽  
Chest Wall Resection ◽  
Chest Wall Tumor ◽  
Imaging Features ◽  
Malignant Phyllodes Tumor ◽  
Chest Wall Invasion ◽  
Epithelial Component ◽  
Stromal Component ◽  
Wall Invasion

We present a case of a 63-year-old woman with malignant phyllodes tumor in her left breast. On imaging, a large, dumbbell-shaped, predominantly cystic mass with thin peripheral enhancement was noted. The lesion was causing rib destruction, chest wall invasion, and intrathoracic extension. These aggressive imaging features were considered highly suspicious of a malignant chest wall tumor. Subsequent chest wall resection of the tumor showed breast tissue with a biphasic lesion composed of proliferated spindle cells in loose sheets with extensive islands of atypical cartilage and a scanty epithelial component, including compressed ducts in the periphery of the lesion. A diagnosis of a malignant phyllodes tumor with stromal overgrowth and chondrosarcomatous differentiation was made in view of the presence of a benign epithelial component and negative reaction of the stromal component with a pancytokeratin. To the best of our knowledge, a phyllodes tumor with the radiological features of chest wall invasion and intrathoracic extension has not been described in the literature until now. Malignant phyllodes should be included in the list of differentials along with sarcomas on encountering lesions with such aggressive imaging features.

scholarly journals Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Canan Kelten ◽  
Ceren Boyaci ◽  
Cem Leblebici ◽  
Kemal Behzatoglu ◽  
Didem C. Trabulus ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Cyst ◽  
Clinical Breast Examination ◽  
Phyllodes Tumor ◽  
Breast Cancer Diagnosis ◽  
Left Breast ◽  
Malignant Phyllodes Tumor ◽  
Her Family ◽  
Simple Mastectomy ◽  
Clinical Breast

Background: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. Case Report: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed. However, the biopsy was diagnosed as malignant phyllodes tumor. An evaluation by ultrasonography showed a well-defined hypoechoic mass with many cystic spaces covering the entire breast tissue. Therefore, a simple mastectomy was performed. Microscopic examination revealed a high-grade malignant phyllodes tumor. Additionally, bone cyst-like areas in the form of sponge-like blood-filled non-endothelialized spaces were observed. Conclusions: Since the breasts become larger due to the physiological changes during pregnancy, any underlying breast lesions may be obscured. Therefore, clinical breast examination in the first visit of pregnancy is important.

scholarly journals Preoperative interventional artery embolization for the treatment of a giant malignant phyllodes tumor: A case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Yue Tian ◽  
Linlin Liu ◽  
Liang Chen ◽  
Shengdi Zhao ◽  
Ruijun Su ◽  
...  
Keyword(s):  
Case Report ◽  
Phyllodes Tumor ◽  
Artery Embolization ◽  
Malignant Phyllodes Tumor

scholarly journals Radiotherapy was Effective for Multiple Organ Metastases of a Malignant Phyllodes Tumor—A Case Report—

2018 ◽  
Vol 79 (10) ◽  
pp. 2020-2026
Author(s):  
Tomohiro OSHINO ◽  
Nobumoto TOMIOKA ◽  
Kenichi WATANABE ◽  
Masako SATO ◽  
Mitsugu YAMAMOTO ◽  
...  
Keyword(s):  
Case Report ◽  
Phyllodes Tumor ◽  
Multiple Organ ◽  
Malignant Phyllodes Tumor

scholarly journals Malignant Phyllodes Tumor in an Adolescent Female: A Rare Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Gabriel S. Makar ◽  
Michael Makar ◽  
Joanna Ghobrial ◽  
Kathryn Bush ◽  
Ryan Allen Gruner ◽  
...  
Keyword(s):  
Breast Neoplasms ◽  
Rare Case ◽  
Phyllodes Tumor ◽  
Adolescent Females ◽  
Small Subset ◽  
Review Of The Literature ◽  
Malignant Phyllodes Tumor ◽  
Phyllodes Tumors ◽  
Rare Case Report

Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify these tumors early allowing for prompt resection and close follow-up. Here, we present the rare case of a 17-year-old female presenting with a rapidly enlarging breast mass, which was ultimately found to be a malignant phyllodes tumor. We further performed a review of the literature to highlight only 22 other cases reported in adolescent females.

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