scholarly journals Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Canan Kelten ◽  
Ceren Boyaci ◽  
Cem Leblebici ◽  
Kemal Behzatoglu ◽  
Didem C. Trabulus ◽  
...  

Background: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. Case Report: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed. However, the biopsy was diagnosed as malignant phyllodes tumor. An evaluation by ultrasonography showed a well-defined hypoechoic mass with many cystic spaces covering the entire breast tissue. Therefore, a simple mastectomy was performed. Microscopic examination revealed a high-grade malignant phyllodes tumor. Additionally, bone cyst-like areas in the form of sponge-like blood-filled non-endothelialized spaces were observed. Conclusions: Since the breasts become larger due to the physiological changes during pregnancy, any underlying breast lesions may be obscured. Therefore, clinical breast examination in the first visit of pregnancy is important.

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kimihisa Mizoguchi ◽  
Kazuhisa Kaneshiro ◽  
Makoto Kubo ◽  
Yoshihiko Sadakari ◽  
Yoshizo Kimura ◽  
...  

Abstract Background Granulocyte-colony stimulating factor (G-CSF)-producing tumors can cause leukocytosis despite an absence of infection. G-CSF-producing tumors have been reported in various organs such as the lung, esophagus, and stomach but rarely in the breast. We report a case of G-CSF-producing malignant phyllodes tumor of the breast. Case presentation An 84-year-old woman visited our hospital complaining of a lump in her left breast without fever and pain. Laboratory tests revealed elevated white blood cell (WBC) count and G-CSF levels. A malignant tumor of the breast was diagnosed by core needle biopsy. We performed a total mastectomy and sentinel lymph node biopsy. The tumor was identified as a G-CSF-producing malignant phyllodes tumor. Within 7 days after surgery, the patient’s WBC count and G-CSF level had decreased to normal levels. She is alive without recurrence 13 months after surgery. Conclusions We encountered a rare case of G-CSF-producing malignant phyllodes tumor of the breast. PET–CT revealed diffuse accumulation of FDG in the bone. Phyllodes tumors need to be differentiated from bone metastasis, lymphoma, and leukemia. We must be careful to not mistake this type of tumor for bone marrow metastasis.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Yue Tian ◽  
Linlin Liu ◽  
Liang Chen ◽  
Shengdi Zhao ◽  
Ruijun Su ◽  
...  

2018 ◽  
Vol 79 (10) ◽  
pp. 2020-2026
Author(s):  
Tomohiro OSHINO ◽  
Nobumoto TOMIOKA ◽  
Kenichi WATANABE ◽  
Masako SATO ◽  
Mitsugu YAMAMOTO ◽  
...  

2016 ◽  
Vol 36 (1) ◽  
pp. 61-64 ◽  
Author(s):  
Sidra Hassan ◽  
Nasir Ud Din ◽  
Naila Kayani

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
R. A. Amir ◽  
Rola S. Rabah ◽  
S. S. Sheikh

Phyllodes tumor (PT) is a rare tumor of the breast accounting for approximately 1% of all breast neoplasms. In 1838, J. Muller coined the term “cystosarcoma phyllodes” based on the leaf-like projections of the tumor extending into the cystic spaces and sarcomatous stromal growth. However, seeing as up to 70% of phyllodes tumors are benign, “cystosarcoma” was removed, and the tumor is now recognized simply as phyllodes tumor. It is mainly seen in females between the ages of 35 and 55. Although most phyllodes tumors are benign, malignant cases do uncommonly occur, 22% of which have distant metastasis typically to the lungs and bones. Rarely, this tumor metastasizes to other locations. Herein, we report a case of malignant phyllodes tumor with metastasis to the pancreas. According to our knowledge, only 3 case reports of pancreatic metastasis from malignant phyllodes tumor have been reported in literature thus far. We aim to increase awareness among physicians of this rare metastasic potential of the uncommonly encountered malignant phyllodes tumor.


2018 ◽  
Vol 06 (01) ◽  
Author(s):  
Imen Znagui ◽  
Slimani Olfa ◽  
Attia Moez ◽  
Ben Temim Riadh ◽  
Makhlouf Taher ◽  
...  

Breast Cancer ◽  
2009 ◽  
Vol 17 (3) ◽  
pp. 218-224 ◽  
Author(s):  
Satomi Suzuki-Uematsu ◽  
Kazuko Shiraishi ◽  
Taro Ito ◽  
Naoki Adachi ◽  
Yoshihisa Inage ◽  
...  

2012 ◽  
Vol 3 (2) ◽  
pp. 1-9
Author(s):  
Damon D Shearer ◽  
Ryan W Askeland ◽  
Jeong Mi Park ◽  
Laurie L Fajardo ◽  
Limin Yang

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