scholarly journals Percutaneous Laser Ablation of Malignant Tumors Under Magnetic Resonance Imaging

1990 ◽  
Vol 11 (Supplement) ◽  
pp. 469-472
Author(s):  
Tsuneo Ishiguchi
Neurosurgery ◽  
2007 ◽  
Vol 61 (5) ◽  
pp. E1101-E1104 ◽  
Author(s):  
Shin-Ichi Miyatake ◽  
Toshihiko Kuroiwa ◽  
Yoshinaga Kajimoto ◽  
Minoru Miyashita ◽  
Hidekazu Tanaka ◽  
...  

Abstract OBJECTIVE It has been established that fluorescence-guided resection using 5-aminolevulinic acid is useful in glioma surgery. In this study, we describe three cases in which even perinecrotic tissue could be recognized as fluorescence positive. METHODS Three cases of central nervous system disease, showing gadolinium enhancement on magnetic resonance imaging scans, were operated on with the aid of fluorescence derived from 5-aminolevulinic acid. Two of these were diagnosed as radiation necrosis and the other as a neurodegenerative demyelinating disease. RESULTS In all cases, at least some parts of the gadolinium-enhanced area could be labeled as fluorescence positive, whereas centers of necrotic tissue were negative for fluorescence. Histologically, cell infiltration was marked in each case that showed fluorescence activity. CONCLUSION Both malignant tumors and the perinecrotic area in radiation necrosis or neurodegenerative disease can be labeled as fluorescence positive using 5-aminolevulinic acid.


2017 ◽  
Vol 198 (4) ◽  
pp. 839-847 ◽  
Author(s):  
Shyam Natarajan ◽  
Tonye A. Jones ◽  
Alan M. Priester ◽  
Rory Geoghegan ◽  
Patricia Lieu ◽  
...  

2021 ◽  
Vol 11 (2) ◽  
pp. 10-17
Author(s):  
E. G. Khazarova ◽  
E. L. Dronova

Introduction. Сomputed tomography (СТ) and magnetic resonance imaging (MRI) are the main methods of radiological diagnostics, which makes it possible to objectively assess the local advancement of malignant tumors of the hearing organ and decide on the possibility of surgical intervention.The objective of this scientific research – to determine the main indications for surgical intervention, taking into account the radiological criteria for the lesion of the temporal bone (CT, MRI) in locally advanced outer ear skin cancer. Materials and methods. This research work based on a retrospective and prospective analysis case history for patients with locally advanced external ear skin cancer. These are 45 patients, who received treatment in surgical department of head and neck tumors in N. N. Blokhin National Medical Research Center of Oncology between 1994 and 2020. Patient observation time averaged 30.0 ± 32.3 months (from 0.7 to 117.4 months, median – 12.0 months).Results. The prevalence of the tumor process in cancer of the skin of the external auditory canal in accordance with the staging system for lesions of the temporal bone structures (University of Pittsburgh, 1990), which takes into account CT and MRI signs of damage to the temporal bone and adjacent anatomical structures, is a factor that significantly affects the long-term results of treatment (for disease-free survival: hazard ratio (HR) 4.76, 95 % confidence interval (CI) 1.93–11.73, р = 0.00069; for tumor-specific survival: HR 4.25, 95 % CI 1.74–10.39, р = 0.0015; for overall survival: HR 1.96, 95 % CI 1.07–3.58, р = 0.029).Conclusion. CT and MRI are mandatory methods of radiological diagnosis of patients with skin cancer of the external auditory canal.


2018 ◽  
Vol 21 (3) ◽  
pp. 302-307 ◽  
Author(s):  
James M. Wright ◽  
Michael D. Staudt ◽  
Andrea Alonso ◽  
Jonathan P. Miller ◽  
Andrew E. Sloan

The authors describe the case of a 22-month-old boy who presented with gelastic seizures and developmental delay. Magnetic resonance imaging and video-electroencephalography monitoring revealed a primarily intraventricular hypothalamic hamartoma and gelastic seizures occurring 20–30 times daily. The patient was treated with various regimens of antiepileptic medications for 16 months, but the seizures remained medically intractable. At 3 years of age, he underwent stereotactic laser ablation with an aim of disconnection of the lesion. The procedure was performed with the NeuroBlate SideFire probe. To the authors’ knowledge, this is the first reported use of this technology for this procedure and serves as proof of concept. There were no perioperative complications, and 2 years postprocedure, the patient remains seizure free with marked behavioral and cognitive improvements.


2016 ◽  
Vol 196 (6) ◽  
pp. 1670-1675 ◽  
Author(s):  
Scott E. Eggener ◽  
Ambereen Yousuf ◽  
Sydeaka Watson ◽  
Shiyang Wang ◽  
Aytekin Oto

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