HIGH FREQUENCY OF RECENT ISCHEMIC STROKE IN PATIENTS WITH PULMONARY EMBOLISM AND PATENT FORAMEN OVALE SUGGESTS THAT PARADOXICAL EMBOLISM IS A FREQUENT MECHANISM

Author(s):  
Serge Timsit
Author(s):  
Prasanna Venkatesan Eswaradass ◽  
Sadanand Dey ◽  
Dilip Singh ◽  
Michael D. Hill

AbstractSilent pulmonary embolism (PE) may be associated with acute ischemic stroke (AIS). We identified 10 patients from 3,132 unique patients (3,431 CT scans). We retrospectively examined CT angiogram of patients with AIS to determine the frequency of concurrent PE in AIS. The period prevalence of PE was 0.32. Seven patients had concurrent PE, whereas three had PE diagnosed 2 days after their AIS presentation. We suspected paradoxical embolism via patent foramen ovale as the cause of stroke in three patients and thrombophilia in four patients. Seven patients had poor outcome including four deaths. CT angiogram stroke protocol images from aortic arch to vertex allows visualization of upper pulmonary arteries and PE detection in AIS.


2021 ◽  
Vol 2021 (10) ◽  
Author(s):  
Kiyoshi Takemoto ◽  
Michitaka Nakamura ◽  
Kazuaki Atagi

ABSTRACT A patent foramen ovale (PFO) is a cause of paradoxical embolism. Although most patients with a PFO are asymptomatic, various clinical manifestations may be associated with PFO. The most important is a cryptogenic stroke. Concomitant acute pulmonary embolism (APE), acute myocardial infarction (AMI) and acute ischemic stroke (AIS) due to paradoxical embolism from a PFO are extremely rare. We describe a 77-year-old woman with a past medical history of hypertension who was transferred due to a sudden onset of dyspnea followed by cardiopulmonary arrest. Based on the patient’s medical history, transthoracic and transesophageal echocardiography, coronary angiography, and a whole-body contrasted computed tomography, we diagnosed concomitant APE, AMI and AIS caused by a paradoxical embolism from a PFO. Appropriate knowledge of the pathophysiology of this rare critical illness is important for prompt diagnosis and treatment.


2019 ◽  
Vol 171 (7) ◽  
pp. 527
Author(s):  
Preetham Kumar ◽  
M. Khalid Mojadidi ◽  
Bernhard Meier ◽  
Jonathan M. Tobis

2019 ◽  
Vol 171 (7) ◽  
pp. 527
Author(s):  
Emmanuelle Le Moigne ◽  
Yannick Jobic ◽  
Serge Timsit ◽  
Clément Hoffmann ◽  
Francis Couturaud

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