CEFOTAXIME-INDUCED DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS) COMPLICATED BY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH)

2018 ◽  
Author(s):  
Zafer Kurugol
Keyword(s):  
Drug Reaction ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Systemic Symptoms

Overlap between hemophagocytic lymphohistiocytosis and drug reaction and eosinophilia with systemic symptoms: a review

2020 ◽  
Author(s):  
Jason J. Yang ◽  
Donald K. Lei ◽  
Vignesh Ravi ◽  
Nolan J. Maloney ◽  
Ashley Crew ◽  
...  
Keyword(s):  
Drug Reaction ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Systemic Symptoms

Ceftazidime-induced drug reaction with eosinophilia and systemic symptoms (DRESS) complicated by hemophagocytic lymphohistiocytosis

2013 ◽  
Vol 1 (4) ◽  
pp. 409-412.e2 ◽  
Author(s):  
Matthieu Picard ◽  
M. Isabel Fernandez ◽  
Anne Des Roches ◽  
Philippe Bégin ◽  
Jean Paradis ◽  
...  
Keyword(s):  
Drug Reaction ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Systemic Symptoms

Drug reaction with eosinophilia and systemic symptoms (DRESS)‐associated hemophagocytic lymphohistiocytosis (HLH), an important and underrecognized HLH mimic: A case report

2020 ◽  
Vol 68 (2) ◽  
Author(s):  
Maria Carter Febres ◽  
James Abbott ◽  
Sarah D. Cipriano ◽  
Elizabeth Doby Knackstedt ◽  
Tracy I. George ◽  
...  
Keyword(s):  
Drug Reaction ◽  
Case Report ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Systemic Symptoms

When fever is more than infection: two cases of vancomycin-induced drug reaction with eosinophilia and systemic symptoms (DRESS)

2021 ◽  
Vol 14 (1) ◽  
pp. e238006
Author(s):  
Mitchell Cox ◽  
Sophie Paviour ◽  
Sophie Gregory ◽  
Rusheng Chew
Keyword(s):  
Drug Reaction ◽  
Cytomegalovirus Reactivation ◽  
First Case ◽  
Metropolitan Hospital ◽  
Orthopaedic Ward ◽  
Systemic Hypersensitivity ◽  
Systemic Symptoms ◽  
Inflammatory Syndrome ◽  
Intravenous Glucocorticoids

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, but serious systemic hypersensitivity reaction associated with a range of medications. We present two cases of vancomycin-induced DRESS, which occurred simultaneously in the orthopaedic ward in an outer metropolitan hospital. These cases demonstrate the complexity in the diagnosis and management of this inflammatory syndrome on the background of known infection as well as evidence for linezolid as an alternative to vancomycin. The first case was managed conservatively, but developed progressive renal and liver injury along with demonstrated cytomegalovirus reactivation and recurrent colitis, and was eventually palliated. The second was commenced on intravenous glucocorticoids and achieved remission, although had ongoing renal dysfunction at the time of discharge from outpatient follow-up.

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