scholarly journals Transoral robotic surgery and neck dissection as primary treatment results in reduced adjuvant treatment for patients with advanced oropharyngeal squamous cell cancer

2018 ◽  
Author(s):  
Harry Tustin
Keyword(s):  
Robotic Surgery ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Adjuvant Treatment ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Primary Treatment ◽  
Transoral Robotic Surgery ◽  
Treatment Results

Results of Combined Radiotherapy and Multidrug Chemotherapy in Advanced Squamous Cell Cancer of the Head and Neck

1986 ◽  
Vol 72 (5) ◽  
pp. 487-490
Author(s):  
Marian Reinfuss ◽  
Stanislaw Korzeniowski
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Treatment Results ◽  
Free Survival ◽  
Multidrug Chemotherapy ◽  
Radio Chemotherapy ◽  
Higher Doses

Treatment results of combined radiotherapy and polychemotherapy in a group of 38 patients with advanced squamous cell of the head and neck cancer are presented. The radio-chemotherapy schedule included 60Co irradiation with 20 Gy in 10 fractions over two weeks followed by multidrug chemotherapy with vincristin, bleomycin, methotrexate and leucovorin. Three series of radio-chemotherapy were given. In 14 patients the total dose of irradiation was increased to 70-105 Gy. The probabilities of overall and symptom-free survival at 2 years were 32% and 20%, respectively. Treatment results correlated with stage of the disease. Patients who received higher doses of radiation seemed to have better chances of symptom-free survival.

Cervical node metastases in oropharyngeal squamous cell carcinoma: prospective analysis of prevalence and distribution

2002 ◽  
Vol 116 (11) ◽  
pp. 925-928 ◽  
Author(s):  
Jemy Jose ◽  
Andrew P. Coatesworth ◽  
Colin Johnston ◽  
Ken MacLennan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Oropharyngeal Carcinoma ◽  
Neck Node ◽  
Cancer Metastases ◽  
Node Metastases

The treatment of cervical lymph node metastases is an important part of the management of oropharyngeal squamous cell cancer. Metastases are already clinically present in 61 per cent (+ or −2.6 per cent) of patients at presentation. Previous studies concerning the prevalence and distribution of neck node metastases in oropharyngeal carcinoma have been retrospective, and little or no information is available about the histopathological methods used.This study has prospectively analysed 85 neck dissection specimens in 72 consecutive patients with squamous cell carcinoma of the oropharynx, both with clinically N0 and N+ve necks, to identify the prevalence and distribution of cervical metastases. We have used a technique to separate the neck dissection into nodal levels per-operatively, and then embedded the entire specimen for histological examination to avoid missing metastatic disease in small lymph nodes (<3mm diameter).

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