Pancreatic Mass Mimicking Neuroendocrine Tumor

A 68-year-old man presented to our hospital for the evaluation of an incidentally detected pancreatic mass. Serum tumor marker levels were within normal limits. On delayed-phase computed tomography, a homogeneous enhancing 1.8 cm-sized hypervascular mass was detected in the pancreatic head (Figure 1). As the radiologic impression was that of a neuroendocrine tumor, the patient underwent pylorus-preserving pancreatoduodectomy. Microscopically, the tumor exhibited typical features of pancreatic solid hamartoma (Figure 2). Pancreatic solid hamartoma is an extremely rare entity that shows components that are present in the normal pancreas with distorted architecture and are considered as malformative lesions. Preoperative diagnosis is difficult because the clinicopathological features of solid hamartoma have not yet been fully clarified. The radiologic findings in this mass were similar to those of a neuroendocrine tumor. All patients with pancreatic hamartomas present with a benign clinical course. Recognition of this entity is desirable to avoid unnecessary extended surgical resection.

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Urachal remnant carcinoma - a rare entity

South African Journal of Radiology ◽

10.4102/sajr.v17i2.246 ◽

2013 ◽

Vol 17 (2) ◽

pp. 63-64

Author(s):

Vanesha Naidu ◽

Narisha Maharaj ◽

Ayesha Mitha ◽

Jaynund Maharajh ◽

Bhugwan Singh

Keyword(s):

Clinical Course ◽

Late Presentation ◽

Imaging Features ◽

Rare Entity ◽

Primary Malignancy ◽

Urachal Carcinoma ◽

Urachal Remnant ◽

Characteristic Imaging ◽

Sister Mary Joseph’S Nodule ◽

Initial Clinical Evaluation

Primary malignancy of the urachal remnant is a rare neoplasm that accounts for less than 0.01% of all adult cancers, with an estimated annual incidence of 1:5 million. The tumour carries a grave prognosis that attests to its highly aggressive nature. Owing to its extra-peritoneal location, the tumour runs a relatively silent clinical course until late presentation, when most patients display extensive local invasion and metastatic spread. In this report, we highlight a case of primary malignancy of the urachus that on initial clinical evaluation masqueraded as a Sister Mary Joseph’s nodule. Characteristic imaging features, however, proved decisive in establishing the diagnosis of a urachal carcinoma.

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Primary Small Cell Neuroendocrine Tumor of the Liver: A Rare Entity

The American Journal of Gastroenterology ◽

10.14309/00000434-201810001-02277 ◽

2018 ◽

Vol 113 (Supplement) ◽

pp. S1287

Author(s):

Colin Leffert ◽

Areej Mazhar

Keyword(s):

Neuroendocrine Tumor ◽

Small Cell ◽

Rare Entity

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Papillary thyroid carcinoma with exuberant nodular fasciitis-like stroma: treatment outcome and prognosis

The Journal of Laryngology & Otology ◽

10.1017/s0022215106000211 ◽

2006 ◽

Vol 120 (4) ◽

pp. 338-342 ◽

Cited By ~ 10

Author(s):

S Basu ◽

N Nair ◽

T Shet ◽

A M Borges

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Clinical Course ◽

Nodular Fasciitis ◽

Rare Entity ◽

Papillary Thyroid ◽

Radioiodine Treatment ◽

Long Term Follow Up

Papillary thyroid carcinoma with nodular fasciitis-like stroma (PTC-NFS) is one of the extremely rare variants of papillary thyroid carcinoma. To date, the majority of reported cases have been published in the surgical pathology and cytopathology literature, addressing the diagnostic difficulties posed by the condition's extensive, reactive stromal proliferation. Because of the rarity of PTC-NFS among papillary thyroid carcinoma variants, it has been unexplored from a clinical viewpoint. A MEDLINE search on the clinical course, role of radioiodine, treatment outcome and long term follow up of this disease yielded no result.We report the clinicoradiologic and histopathologic profile, together with post-treatment long term follow up, in a 35-year-old woman harbouring this rare entity. To the best of our knowledge, this is the first report of a five-year follow up of this rare variant of PTC following total thyroidectomy and radioiodine treatment. Our follow-up findings reiterate the disease's favourable clinical course when managed in the same manner as a classical, differentiated papillary carcinoma of the thyroid, akin to that predicted by the pathologists, and emphasize the importance of differentiating PTC-NFS as a separate entity from the papillary carcinoma variants with aggressive histology. Given the rarity of this condition, the experience gained from the present case is a useful addition to the current knowledge on disease prognostication and management.A systematic review of the existing literature on PTC-NFS, including the case reported in the present paper, is also carried out, aiming to explore the patient characteristics and clinical behaviour pattern of this rare entity and to make appropriate recommendations on management strategy. The age of presentation ranges from 20 to 82 years, with a mean of 44.5 years. Female preponderance was observed, with a female to male ratio of 3[ratio ]1. No racial predilection was observed. Tumour size varied from 2 to 9 cm along its greatest diameter (mean = 4.3 cm). Metastasis to lymph nodes at presentation occurred in 25 per cent of cases. Metastasis to surrounding structures (e.g. parathyroid and skeletal muscle) was observed in 12.5 per cent. There have been no reports of pulmonary or skeletal metastasis at presentation.

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Aggressive Angiomyolipomas: the Clandestine Epithelioid Variant

Current Urology ◽

10.1159/000442853 ◽

2015 ◽

Vol 9 (1) ◽

pp. 54-56 ◽

Cited By ~ 1

Author(s):

Anton Maré ◽

Shehan Wickramasinghe ◽

Victor Ilie ◽

Maurice Mulcahy

Keyword(s):

Distant Metastasis ◽

Clinical Course ◽

Case Reports ◽

Malignant Potential ◽

Benign Tumour ◽

Rare Entity ◽

Epithelioid Angiomyolipoma ◽

Epithelioid Variant

Epithelioid angiomyolipoma is a rare mesenchymal derived neoplasm of the kidney. Thought to be a variant of classical angiomyolipoma, a benign tumour, its malignant potential has been highlighted by case reports of loco-regional and distant metastasis. Given the potentially adverse clinical course associated with epithelioid angiomyolipoma compared to classical angiomyolipoma, the distinction and comprehensive histological characterisation of this rare entity is essential.

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Intravascular Papillary Endothelial Hyperplasia Associated with Venous Pool Arising in the Lower Lip: A Case Report

International Journal of Dentistry ◽

10.1155/2009/940686 ◽

2009 ◽

Vol 2009 ◽

pp. 1-5 ◽

Cited By ~ 3

Author(s):

Hisanobu Yonezawa ◽

Akimitsu Hiraki ◽

Ken-ichi Iyama ◽

Masanori Shinohara

Keyword(s):

Endothelial Cells ◽

Vascular Tissue ◽

Clinical Course ◽

Histopathological Examination ◽

Vascular Lesion ◽

Intravascular Papillary Endothelial Hyperplasia ◽

Lower Lip ◽

Radiologic Findings ◽

Papillary Endothelial Hyperplasia ◽

Benign Nature

Intravascular papillary endothelial hyperplasia is a benign nonneoplastic vascular lesion that consists of endothelial cells with abundant vascular tissue with papillary proliferation. An adult female had a painless growing dark red nodule on the left side of the lower lip and often touched and gnawed at it for more than 4 years. The lesion was a tender, smooth mass approximately 1 cm in diameter without discoloration reaction. Magnetic resonance imaging of the lesion showed specific findings. She was diagnosed clinically as having mimicked hemangioma, and the lesion was totally excised under local anesthesia. Histopathological examination revealed that papillary proliferated endothelial cells with venous pool, and the lesion was diagnosed as intravascular papillary endothelial hyperplasia associated with venous pool. There has been no recurrence for more than 1 year. Despite the benign nature of this lesion, it could have been mistaken for a malignant tumor because of its clinical course and radiologic findings.

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Primary pleural primitive neuroendocrine tumor: A rare entity

The Journal of Association of Chest Physicians ◽

10.4103/2320-8775.168623 ◽

2016 ◽

Vol 4 (2) ◽

pp. 81

Author(s):

Arjun Khanna ◽

Mayuri Johari ◽

DeepakKumar Prajapat ◽

Deepak Talwar

Keyword(s):

Neuroendocrine Tumor ◽

Rare Entity

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Radiologic Findings of Splenic Abscess: A Report of Two Cases

Gastroenterology Pancreatology and Hepatobilary Disorders ◽

10.31579/2641-5194/043 ◽

2021 ◽

Vol 5 (5) ◽

pp. 01-03

Author(s):

Sule M.B ◽

Umar A.U ◽

Gele I.H ◽

Ribah M.M ◽

Aliyu A.Z

Keyword(s):

Computed Tomography ◽

Mortality Rate ◽

Antimicrobial Agents ◽

Splenic Abscess ◽

Rare Entity ◽

Computed Tomography Scan ◽

Radiologic Findings ◽

First Case ◽

Post Traumatic ◽

Tomography Scan

Splenic abscess is a very rare entity with an incidence of about 0.14-0.7% in autopsy studies. Splenic abscess has been reported to have a mortality rate of about47%, it has various causes but usually associated with trauma and infections of the spleen. We report two cases of splenic abscess; a child with post traumatic cause and a middle aged lady with an unknown cause. Both cases were diagnosed of having the abscess following imaging; the first case had abdominopelvic ultrasound that showed an abscess cavity with a volume of about 11mls and subsequently resolved following medical treatment with intravenous antimicrobial agents. The second case however had an abdominopelvic computed tomography scan that showed a huge splenic abscess with a volume of about 1400mls; she had a successful splenectomy. We report the radiologic findings of these cases due to the rare nature of splenic abscess as reported in the literature.

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Torsion of an Encysted Fluid Collection

The Scientific World JOURNAL ◽

10.1100/tsw.2007.152 ◽

2007 ◽

Vol 7 ◽

pp. 822-824 ◽

Cited By ~ 4

Author(s):

Atilla Senayli ◽

Yesim Senayli ◽

Engin Sezer ◽

Taner Sezer

Keyword(s):

Clinical Course ◽

Fluid Collection ◽

Acute Scrotum ◽

Rare Entity ◽

Tunica Vaginalis ◽

Hernia Sac ◽

Pathologic Evaluation ◽

Testis Torsion

Torsion of a cyst within the tunica vaginalis is a rare entity and clinical course can easily be confused with other diseases that cause acute scrotum. We report a 6-year-old child with 3 days of acute scrotum findings. Patient had surgery with the suspicion of testis torsion. Torsion of a cyst within the tunica vaginalis was found intraoperatively. In pathologic evaluation, a necrotic funicular cyst was diagnosed. Two different mechanisms were reported for the reason of this disease: hernia sac protrusion in the hydrocele sac and bell-clapper deformity. Our observations were on the side of bell-clapper deformity. We aimed to share our findings with this report.

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