scholarly journals Screening of Influenza a (H1N1) Neuraminidase Inhibitor for Kabasura Kudineer, Nilavembu Kudineer and the Novel Formulation JACOM

2021 ◽  
Author(s):  
SHREE DEVI MS ◽  
SATHIYARAJESWARAN P ◽  
Mohanasrinivasan V ◽  
SUBATHRADEVI C ◽  
Ramaswamy RS ◽  
...  
Keyword(s):  
Influenza A ◽  
Tamil Nadu ◽  
Neuraminidase Inhibitor ◽  
Evidence Base ◽  
The Novel ◽  
Vector Borne Diseases ◽  
Neuraminidase Inhibition ◽  
Influenza A H1n1 ◽  
Vector Borne ◽  
Change Vector

<p>Due to erratic climate change, vector-borne diseases started flaring up from the second half of the last decade. Siddha medicine has been used as a public health tool to effectively manage chikungunya and dengue in the epidemics that happened in 2008 and 2016. Tamil Nadu government has made enormous efforts to control vector-borne diseases. Due to which morbidity and mortality due to vector borne diseases came down compared with other states. Two official Siddha formulations, namely Kabasura Kudineer Chooranam and Nilavembu Kudineer Chooranam and novel herbal formulation – JACOM, are used to combat vector-borne diseases. These decoctions lack an evidence base as a formulation. Screening has been done to check the efficacy of the formulation in inhibiting neuraminidase. Neuraminidase inhibition assay was performed to determine the activity of Siddha formulations. The Kabasura Kudineer Chooranam, Nilavembu Kudineer Chooranam and JACOM showed excellent inhibitory activity. The Kabasura Kudineer and Nilavembu Kudineer and JACOM aqueous extract showed maximum neuraminidase inhibition of 80.35%, 91.78% and 87.97%, respectively.</p>

scholarly journals Screening of Influenza a (H1N1) Neuraminidase Inhibitor for Kabasura Kudineer, Nilavembu Kudineer and the Novel Formulation JACOM

2021 ◽  
Author(s):  
SHREE DEVI MS ◽  
SATHIYARAJESWARAN P ◽  
Mohanasrinivasan V ◽  
SUBATHRADEVI C ◽  
Ramaswamy RS ◽  
...  
Keyword(s):  
Influenza A ◽  
Tamil Nadu ◽  
Neuraminidase Inhibitor ◽  
Evidence Base ◽  
The Novel ◽  
Vector Borne Diseases ◽  
Neuraminidase Inhibition ◽  
Influenza A H1n1 ◽  
Vector Borne ◽  
Change Vector

<p>Due to erratic climate change, vector-borne diseases started flaring up from the second half of the last decade. Siddha medicine has been used as a public health tool to effectively manage chikungunya and dengue in the epidemics that happened in 2008 and 2016. Tamil Nadu government has made enormous efforts to control vector-borne diseases. Due to which morbidity and mortality due to vector borne diseases came down compared with other states. Two official Siddha formulations, namely Kabasura Kudineer Chooranam and Nilavembu Kudineer Chooranam and novel herbal formulation – JACOM, are used to combat vector-borne diseases. These decoctions lack an evidence base as a formulation. Screening has been done to check the efficacy of the formulation in inhibiting neuraminidase. Neuraminidase inhibition assay was performed to determine the activity of Siddha formulations. The Kabasura Kudineer Chooranam, Nilavembu Kudineer Chooranam and JACOM showed excellent inhibitory activity. The Kabasura Kudineer and Nilavembu Kudineer and JACOM aqueous extract showed maximum neuraminidase inhibition of 80.35%, 91.78% and 87.97%, respectively.</p>

scholarly journals A comparative study on knowledge and perception of vector borne diseases among rural and urban population in Tamil Nadu

2019 ◽  
Vol 6 (6) ◽  
pp. 2672
Author(s):  
Roselin V. ◽  
Srisanthanakrishnan V.
Keyword(s):  
Urban Population ◽  
Tamil Nadu ◽  
Community Education ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Vector Borne Diseases ◽  
Vector Borne Disease ◽  
Rural And Urban ◽  
Vector Borne ◽  
Knowledge And Practice

Background: Vector-borne diseases (VBD) remain a major public health challenge, in India. Knowledge about VBD, social, demographic and environmental factors strongly influence the vector transmission and results in major outbreaks. Hence this study was conducted to assess knowledge and practice along with environmental conditions prevailing in both rural and urban areas.Methods: Cross sectional study was conducted in rural and urban field practice area of Sri Muthukumaran Medical College and Research Institute, Chennai, during June 2018 to December 2018. A total of 472 participants with 236 participants from each urban and rural area were included. Data was collected using proforma and analysis was done using SPSS 16.Results: Knowledge about VBD like dengue was 63.6% and 76.7% among rural and urban population, respectively. Similarly malaria was known by knows 59.3% and 68.2% of rural and urban participants. Japanese Encephalitis was the least known mosquito borne disease in both the groups. (p=0.0136). Common breeding sites addressed by the rural population were artificial collected water (36.9%) and urban population was dirty water (42.8%).Conclusions: Knowledge and practice of preventing vector borne disease is still lacking among both rural and urban participants. Spreading knowledge about VBD is a part in effective vector borne disease control which can be achieved by community education alone rather than insecticides and sprays.

scholarly journals The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus

2009 ◽  
Vol 54 (13) ◽  
pp. 2168-2170 ◽  
Author(s):  
YunGang He ◽  
GuoHui Ding ◽  
Chao Bian ◽  
Zhong Huang ◽  
Ke Lan ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Influenza A H1n1 ◽  
Hemagglutinin Gene ◽  
Novel Influenza A

scholarly journals What Have We Learned from the Novel Influenza A (H1N1) Pandemic in 2009 for Strengthening Pandemic Influenza Preparedness?

2009 ◽  
Vol 40 (8) ◽  
pp. 673-676 ◽  
Author(s):  
José Santos-Preciado ◽  
Carlos Franco-Paredes ◽  
Isabel Hernandez-Flores ◽  
Ildefonso Tellez ◽  
Carlos Del Rio ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Pandemic ◽  
The Novel ◽  
Influenza A H1n1 ◽  
Novel Influenza A

scholarly journals The novel influenza a (H1N1) infection in infants and children

1970 ◽  
Vol 8 (4) ◽  
pp. 84-90
Author(s):  
Musa Mohd. Nordin
Keyword(s):  
Influenza A ◽  
Infants And Children ◽  
The Novel ◽  
H1n1 Infection ◽  
Medical Sciences ◽  
Influenza A H1n1 ◽  
Spanish Flu ◽  
Novel Influenza A ◽  
In Infants And Children

During the 1918 Spanish Flu pandemic, often described as the most devastating epidemic in recorded history, 1 in 5 person was infected and an estimated 50 million lives were lost. The disease was so widespread and pervasive that even the children had a tune which they skipped rope to: I had a little bird, its name was Enza, I opened the window and In-Flu-Enza. DOI: 10.3329/bjms.v8i4.4705 Bangladesh Journal of Medical Sciences Vol.8(4); October 2009 pp84-90

scholarly journals Subclinical Infection with the Novel Influenza A (H1N1) Virus

2009 ◽  
Vol 49 (10) ◽  
pp. 1622-1623 ◽  
Author(s):  
Jian Yang ◽  
Fan Yang ◽  
Fang Huang ◽  
Jianwei Wang ◽  
Qi Jin
Keyword(s):  
Influenza A ◽  
H1n1 Virus ◽  
The Novel ◽  
Subclinical Infection ◽  
Influenza A H1n1 ◽  
Novel Influenza A

scholarly journals Characterization of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses isolated in four seasons during pandemic and post-pandemic periods in Japan

2013 ◽  
Vol 7 (6) ◽  
pp. 1390-1399 ◽  
Author(s):  
Emi Takashita ◽  
Seiichiro Fujisaki ◽  
Noriko Kishida ◽  
Hong Xu ◽  
Masaki Imai ◽  
...  
Keyword(s):  
Influenza A ◽  
Neuraminidase Inhibitor ◽  
Four Seasons ◽  
Influenza A H1n1
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