Acute on chronic liver failure - Clinical profile, precipitating factors, outcome and predictors of mortality

2019 ◽  
Vol 11 (3) ◽  
pp. 163-170
Author(s):  
T K Anand ◽  
◽  
Hemamala . ◽  
P Padmanabhan ◽  
◽  
...  
Keyword(s):  
Liver Failure ◽  
Chronic Liver ◽  
Clinical Profile ◽  
Precipitating Factors ◽  
Chronic Liver Failure ◽  
Predictors Of Mortality

Clinical profile, natural history, and predictors of mortality in patients with acute-on-chronic liver failure (ACLF)

2015 ◽  
Vol 127 (7-8) ◽  
pp. 283-289 ◽  
Author(s):  
Ivana Mikolasevic ◽  
Sandra Milic ◽  
Mladen Radic ◽  
Lidija Orlic ◽  
Zeljka Bagic ◽  
...  
Keyword(s):  
Natural History ◽  
Liver Failure ◽  
Chronic Liver ◽  
Clinical Profile ◽  
Chronic Liver Failure ◽  
Predictors Of Mortality

Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure

2012 ◽  
Vol 44 (2) ◽  
pp. 166-171 ◽  
Author(s):  
Hitendra Garg ◽  
Ashish Kumar ◽  
Vishal Garg ◽  
Praveen Sharma ◽  
Barjesh Chander Sharma ◽  
...  
Keyword(s):  
Liver Failure ◽  
Chronic Liver ◽  
Clinical Profile ◽  
Chronic Liver Failure ◽  
Predictors Of Mortality

scholarly journals Descriptive study of clinical profile and outcome in patients of acute on chronic liver failure, at a tertiary care center in Northern India

2020 ◽  
Vol 7 (11) ◽  
pp. 1687
Author(s):  
Rakesh Kumar ◽  
Vandana Rana ◽  
Varghese Koshy ◽  
Vandana Gangadharan ◽  
George Koshy
Keyword(s):  
Liver Failure ◽  
Care Center ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Chronic Liver ◽  
Clinical Profile ◽  
Chronic Liver Failure ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Common Cause

Background: Acute-on-chronic liver failure (ACLF) is a recently described syndrome that is characterized by abrupt deterioration in patients with chronic liver disease (CLD) and has high short-term mortality. The aim of this study was to describe the clinical profile, causes and outcomes of ACLF at a tertiary care centre in Northern India.Methods: In this descriptive study of 50 consecutive patients, were included, between August 2015 to January 2018, who were admitted and diagnosed as ACLF as defined by APASL. Causes of acute precipitating event and CLD and outcomes were assessed.Occurrence and severity of organ failure was also assessed.Results: 48 (96 %) were males and 2 (4%) were females with male to female ratio was 24:1. The mean age of male and female subjects was similar, 40.7±9.9 years and 39.2±9.4 years respectively. The most common cause of CLD was alcohol in 50% cases and next most common cause was hepato-tropic viruses HBV infection in 20%, HCV in 6% cases and there was unknown cause in 12 % cases. The most common precipitating factor of acute decompensation was alcohol in 50% cases, hepatotropic viruses in 30% cases. Excluded sepsis and GI bleed as precipitating events. The combined mortality at the end of 1-month and 3-months, in our study was 60%. CLIF-SOFA score was found to be the most reliable scoring system to discriminate between survivors and non survivors. Conclusions: Alcohol was the commonest precipitating cause of ACLF. Organ failures (OFs) are independently predictive of mortality.

scholarly journals Acute-on-Chronic Liver Failure: Etiology of Chronic and Acute Precipitating Factors and Their Effect on Mortality

2019 ◽  
Vol 9 (6) ◽  
pp. 699-703 ◽  
Author(s):  
Atul Gawande ◽  
Gaurav K. Gupta ◽  
Ankit Gupta ◽  
Shashank J. Wanjari ◽  
Vasudha Goel ◽  
...  
Keyword(s):  
Liver Failure ◽  
Chronic Liver ◽  
Precipitating Factors ◽  
Chronic Liver Failure

Acute on chronic liver failure because of acute hepatic insults: Etiologies, course, extrahepatic organ failure and predictors of mortality

2016 ◽  
Vol 31 (4) ◽  
pp. 856-864 ◽  
Author(s):  
Shalimar ◽  
Dharmendra Kumar ◽  
Padmaprakash Kadavoor Vadiraja ◽  
Baibaswata Nayak ◽  
Bhaskar Thakur ◽  
...  
Keyword(s):  
Liver Failure ◽  
Organ Failure ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Predictors Of Mortality

scholarly journals Acute on Chronic Liver Failure—In-Hospital Predictors of Mortality in ICU

2018 ◽  
Vol 8 (2) ◽  
pp. 144-155 ◽  
Author(s):  
Sujay Kulkarni ◽  
Mithun Sharma ◽  
Padaki N. Rao ◽  
Rajesh Gupta ◽  
Duvvuru N. Reddy
Keyword(s):  
Liver Failure ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Predictors Of Mortality

Predictors of Mortality in Patients with Acute on Chronic Liver Failure: Do We Need Sub Classification?

2014 ◽  
Vol 4 ◽  
pp. S4
Author(s):  
Vinit Shah ◽  
Praveen Sharma ◽  
Rinkesh Bansal ◽  
Pankaj Tyagi ◽  
Naresh Bansal ◽  
...  
Keyword(s):  
Liver Failure ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Predictors Of Mortality
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