INDICATION OF RABIES VIRUS BY CYTOPATHOGENIC BIRD POISX VIRUS IN CELLULAR SYSTEMS

2021 ◽  
Author(s):  
K. Yu. Yusifova ◽  
Keyword(s):  
Rabies Virus ◽  
Japanese Quail ◽  
Cellular Systems ◽  
Chronic Infections ◽  
Cell Systems ◽  
Avian Pox

The study was carried out on the cell systems of Japanese quail embryos and chicken fibroblasts infected with smallpox and rabies viruses. Interfering activity between these viruses was observed in the work. The possibility of using avian pox virus as an indicator in chronic infections has been revealed.

scholarly journals Perspectives of Immune Suppression in the Tumor Microenvironment Promoting Oral Malignancy

2018 ◽  
Vol 12 (1) ◽  
pp. 455-465 ◽  
Author(s):  
Nobuo Kondoh ◽  
Masako Mizuno-Kamiya ◽  
Eiji Takayama ◽  
Harumi Kawati ◽  
Naoki Umemura ◽  
...  
Keyword(s):  
Immune Suppression ◽  
Suppressor Cells ◽  
Cellular Systems ◽  
Immune Checkpoints ◽  
Cancer Associated Fibroblasts ◽  
Myeloid Derived Suppressor Cells ◽  
Chronic Infections ◽  
Oral Malignancy ◽  
Cellular Components ◽  
Immune Detection

Introduction:In order to survive, cancers control immune systems and evade immune detection using mediators consisting of immune checkpoint molecules and cellular systems associated with immune suppression.Methodology:During the development of cancer and chronic infections, the immune checkpoints and cellular components including regulatory T cells, myeloid derived suppressor cells and cancer associated fibroblasts are often enhanced as a mechanism of immune subversion and have therefore become very important therapeutic targets.Conclusion:In this review, we will discuss the complexity of immune-suppressive mechanisms in the tumor milieu of cancers, including oral malignancy.

Properties of rabies virus (MNIIVP-74 strain) adapted to Japanese quail embryo cell culture

1979 ◽  
Vol 61 (1-2) ◽  
pp. 61-68 ◽  
Author(s):  
M. S. Bektemirova ◽  
D. F. Osidze ◽  
E. R. Pille ◽  
L. V. Nadaichik ◽  
K. Sh. Matevosyan ◽  
...  
Keyword(s):  
Cell Culture ◽  
Rabies Virus ◽  
Japanese Quail ◽  
Embryo Cell ◽  
Quail Embryo

MODULAR ASSEMBLY OF CELL SYSTEMS BIOLOGY MODELS USING P SYSTEMS

2009 ◽  
Vol 20 (03) ◽  
pp. 427-442 ◽  
Author(s):  
FRANCISCO J. ROMERO-CAMPERO ◽  
JAMIE TWYCROSS ◽  
MIGUEL CÁMARA ◽  
MALCOLM BENNETT ◽  
MARIAN GHEORGHE ◽  
...  
Keyword(s):  
Systems Biology ◽  
Cellular Systems ◽  
P Systems ◽  
Modular Assembly ◽  
Bacterial Colony ◽  
Cell Systems ◽  
Modelling Framework ◽  
Spatial Localisation ◽  
Cellular Compartments

In this paper we propose an extension of a systems/synthetic biology modelling framework based on P systems that explicitly includes modularity. Modularisation in cellular systems can be produced by chemical specificity, spatial localisation and/or temporal modulation within cellular compartments. The first two of these modularisation features, the focus of this paper, can be easily specified and analysed in P systems using sets of rewriting rules to describe chemical specificity and membranes to represent spatial localisation. Our methodology enables the assembly of cell systems biology models by combining modules which represent functional subsystems. A case study consisting of a bacterial colony system is presented to illustrate our approach.

The Quantitative Ultrastructure of the Heart Muscle of Japanese Quail by Hypergravitation, Hypodynamy and Combination

1990 ◽  
Vol 48 (3) ◽  
pp. 188-189
Author(s):  
Anton Bózner ◽  
Mikuláš Gažo ◽  
Jozef Dostál
Keyword(s):  
Japanese Quail ◽  
Heart Muscle ◽  
Relative Size ◽  
Combination Group ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Space Flights ◽  
Group I ◽  
Quantitative Ultrastructure

It is anticipated that Japanese quail /Coturnix coturnix japonica/ will provide animal proteins in long term space flights. Consequently this species of birds is of research interest of international space program INTERCOSMOS. In the year 1987 we reported on an experiment /2/ in which the effect of chronic acceleration of 2 G hypergravitation, the hypodynamy and the simultaneous effect of chronic acceleration and the location in the centre of the turntable of the centrifuge on the protein fractions in skeletal muscles was studied. The ultrastructure of the heart muscle was now in this experiments examined as well.Japanese quail cockerels, aged 48 days were exposed to 2 G hypergravitation /group IV/ in a 6,4 m diameter centrifuge, to hypodynamy /group III/ and their combination /group V/, respectively for 6 days / Fig.1/. The hypodynamy in group III was achieved by suspending the birds in jackets without contact the floor. The group II was located in the centre ofthe turntable of the centrifuge. The control group I. was kept under normal conditions. The quantitative ultrastructure of myocard was evaluated by the methods of Weibel/3/ - this enables to determine the number, relative size and volume of mitochondria volume of single mitochondria, defficiency of mitochondrial cristae and volume of myofibrils.

Label-free, mass-sensitive single-molecule imaging using interferometric scattering microscopy

2020 ◽  
Author(s):  
Nikolas Hundt
Keyword(s):  
Single Molecule ◽  
Cellular Systems ◽  
Single Molecule Imaging ◽  
Label Free ◽  
Measurement Sensitivity ◽  
Mass Distributions ◽  
Quantitative Measurements ◽  
Contrast Mechanism ◽  
Cellular Components ◽  
Scattering Signal

Abstract Single-molecule imaging has mostly been restricted to the use of fluorescence labelling as a contrast mechanism due to its superior ability to visualise molecules of interest on top of an overwhelming background of other molecules. Recently, interferometric scattering (iSCAT) microscopy has demonstrated the detection and imaging of single biomolecules based on light scattering without the need for fluorescent labels. Significant improvements in measurement sensitivity combined with a dependence of scattering signal on object size have led to the development of mass photometry, a technique that measures the mass of individual molecules and thereby determines mass distributions of biomolecule samples in solution. The experimental simplicity of mass photometry makes it a powerful tool to analyse biomolecular equilibria quantitatively with low sample consumption within minutes. When used for label-free imaging of reconstituted or cellular systems, the strict size-dependence of the iSCAT signal enables quantitative measurements of processes at size scales reaching from single-molecule observations during complex assembly up to mesoscopic dynamics of cellular components and extracellular protrusions. In this review, I would like to introduce the principles of this emerging imaging technology and discuss examples that show how mass-sensitive iSCAT can be used as a strong complement to other routine techniques in biochemistry.

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