Factors regulating apoptosis and homeostasis of CD4+CD25highFOXP3+ regulatory T cells are new therapeutic targets

10.2741/2775 ◽  
2008 ◽  
Vol 13 (13) ◽  
pp. 1472 ◽  
Author(s):  
Xiao-Feng Yang
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Therapeutic Targets ◽  
New Therapeutic Targets

scholarly journals Tissue resident regulatory T cells: novel therapeutic targets for human disease

2015 ◽  
Vol 12 (5) ◽  
pp. 543-552 ◽  
Author(s):  
Xiaohui Zhou ◽  
Jiayou Tang ◽  
Hao Cao ◽  
Huimin Fan ◽  
Bin Li
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Human Disease ◽  
Therapeutic Targets ◽  
Novel Therapeutic

scholarly journals Regulatory T cells as therapeutic targets in rheumatoid arthritis

2009 ◽  
Vol 5 (10) ◽  
pp. 560-565 ◽  
Author(s):  
Jonathan H. Esensten ◽  
David Wofsy ◽  
Jeffrey A. Bluestone
Keyword(s):  
Rheumatoid Arthritis ◽  
T Cells ◽  
Regulatory T Cells ◽  
Therapeutic Targets

scholarly journals Epigenetic enzymes are the therapeutic targets for CD4+CD25+/highFoxp3+ regulatory T cells

2015 ◽  
Vol 165 (1) ◽  
pp. 221-240 ◽  
Author(s):  
Jahaira Lopez-Pastrana ◽  
Ying Shao ◽  
Valeria Chernaya ◽  
Hong Wang ◽  
Xiao-Feng Yang
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Therapeutic Targets

Regulatory T cells in autoimmunity and potential therapeutic targets

2022 ◽  
pp. 55-82
Author(s):  
Ankur Kumar Jindal ◽  
Aaqib Zaffar Banday ◽  
Rahul Tyagi
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Therapeutic Targets

Dysfunctional Regulatory T Cells in Patients with Autoimmune Myasthenia Gravis: Therapeutic Targets? (PD6.006)

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. PD6.006-PD6.006
Author(s):  
M. Meriggioli ◽  
T. Muthusamy ◽  
J. Rowin ◽  
J. R. Sheng ◽  
B. Prabhakar
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Myasthenia Gravis ◽  
Therapeutic Targets ◽  
Autoimmune Myasthenia

New therapeutic targets for antiphospholipid syndrome

Blood ◽  
2007 ◽  
Vol 110 (13) ◽  
pp. 4141-4141
Author(s):  
Tatsuya Atsumi
Keyword(s):  
T Cells ◽  
Antiphospholipid Syndrome ◽  
Cd4 T Cells ◽  
Essential Role ◽  
Therapeutic Targets ◽  
Specific Targeting ◽  
Glycoprotein I ◽  
New Therapeutic Targets ◽  
Anti Phospholipid Syndrome

In this issue of Blood, Yamaguchi and colleagues demonstrated the essential role of the β2-glycoprotein I (β2GPI)/phosphatidylserine complex opsonized by IgG anti-β2GPI antibodies in the proliferation of CD4+ T cells in patients with anti-phospholipid syndrome. Their findings provide novel clues for specific targeting therapies in the affected patients.

scholarly journals An unconventional view of COVID-19 T cell immunity

2020 ◽  
Vol 217 (12) ◽  
Author(s):  
Hui-Fern Koay ◽  
Thomas S. Fulford ◽  
Dale I. Godfrey
Keyword(s):  
T Cells ◽  
T Cell ◽  
Therapeutic Targets ◽  
T Cell Immunity ◽  
Cell Immunity ◽  
New Therapeutic Targets

In this issue of JEM, Jouan et al. (https://doi.org/10.1084/jem.20200872) report the activation and skewed function of unconventional T cells in severe COVID-19 patients. This may reflect a role in COVID-19 immunity or pathogenesis and potentially identifies new therapeutic targets for this disease.

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