scholarly journals Merkel Cell Carcinoma of Anal Canal: Case Report and Literature Review

2021 ◽  
pp. 245
Author(s):  
◽  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Physical Examination ◽  
Anal Canal ◽  
Cell Carcinoma ◽  
Neuroendocrine Tumor ◽  
Merkel Cell Carcinoma ◽  
Anal Pain ◽  
Merkel Cell ◽  
Chronic Anemia

Few cases of anal canal Merkel cell Carcinoma have been reported in the literature. Merkel Cell Carcinoma is rare neuroendocrine tumor which commonly found in sun-exposed areas such as extremities. We describe a case of 74-year-old male with anal canal Merkel Cell Carcinoma. He presented with peri-anal pain, tenesmus and itching. Besides, he was found to have chronic anemia. An anal nodule was found during per-rectum physical examination that was excised during endoscopy. Histological examination of the nodule confirmed the diagnosis of Merkel Cell Carcinoma. Thenceforward, patient died 7 months after diagnosis with marked metastatic disease despite initiation of Pembrolizumab therapy.

scholarly journals Merkel cell carcinoma: a case report and literature review

2021 ◽  
Author(s):  
Soulé-Martínez Christian Enrique ◽  
Monroy-Ramírez Miguel Angel ◽  
Jaimes-Durán Edwing Michel ◽  
Castellanos-Aguilar Leonel ◽  
Ricarte-Almeida Eros Rafael ◽  
...  
Keyword(s):  
Case Report ◽  
Survival Rate ◽  
Mortality Rate ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Neuroendocrine Tumor ◽  
Merkel Cell Carcinoma ◽  
The Elderly ◽  
Merkel Cell ◽  
Prompt Diagnosis

Merkel cell carcinoma (MCC) is a rare, but highly aggressive, malignant neuroendocrine tumor, with a higher prevalence in men, Caucasians, and the elderly. It is usually identified in photo-exposed areas such as the head, trunk, and extremities. It is related to locoregional recurrences and metastases, which conditions a high mortality rate. Currently, the pathogenesis is unclear, but it is related to ultraviolet radiation, immunosuppression, and polyomavirus infection. Prompt diagnosis and treatment are essential to improve the survival rate.

scholarly journals Primary retroperitoneal Merkel cell carcinoma: Case report and literature review

2016 ◽  
Vol 19 ◽  
pp. 21-24 ◽  
Author(s):  
Osvaldo A. Quiroz-Sandoval ◽  
Mario Cuellar-Hubbe ◽  
Leonardo S. Lino-Silva ◽  
Rosa A. Salcedo-Hernández ◽  
Horacio N. López-Basave ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Merkel Cell ◽  
Primary Retroperitoneal

scholarly journals Merkel cell carcinoma of the vulva – case report and the literature review

2013 ◽  
Vol 84 (5) ◽  
Author(s):  
Joanna Jońska-Gmyrek ◽  
Piotr Bobkiewicz ◽  
Leszek Gmyrek ◽  
Agnieszka Żółciak-Siwińska ◽  
Bogusław Lindner ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Merkel Cell

scholarly journals Merkel cell carcinoma: a case report and literature review

2019 ◽  
Vol 2019 (11) ◽  
Author(s):  
Nicholas Mulchan ◽  
Alberto Cayton ◽  
Armand Asarian ◽  
Philip Xiao
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Surgical Excision ◽  
Merkel Cell ◽  
Cutaneous Malignancy ◽  
Uncommon Presentation ◽  
Prevalent Virus ◽  
Time Of Presentation

Abstract Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy of neuroendocrine origin presenting as a painless, rapidly growing nodule. MCC often presents in elderly, fair-skinned individuals in sun-exposed areas. Diagnosis is often overlooked at time of presentation due to its rarity, but MCC is twice as deadly as malignant melanoma. There has been bigger interest in the disease due to increasing incidence and an association with the prevalent virus Merkel cell polyomavirus. This study describes an uncommon presentation of MCC as a right gluteal lesion in an Afro-Panamanian patient. The tumor was suspected to be fibrolipoma, but Immunohistochemistry revealed the diagnosis of MCC, as stains for CD56 and CK20 were positive. In addition to surgical excision, the patient was referred for adjuvant radiotherapy. This case report and literature review elucidates the clinical, histopathologic and management aspects of MCC, which will help in recognizing and treating these tumors.

Merkel cell carcinoma of the forehead area: a literature review and case report

2019 ◽  
Vol 23 (3) ◽  
pp. 365-373 ◽  
Author(s):  
Claudio Caldarelli ◽  
Umberto Autorino ◽  
Caterina Iaquinta ◽  
Andrea De Marchi
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Merkel Cell
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