Integrating technology with instruction using a learner-centered pedagogy, enhances student engagement with learning. Effective technology-integrated instruction involves providing high-quality lesson design, with opportunities for inquiry-based learning, while building a community of learners within a technology-rich classroom (e-MINTS, 2016). For first-year teachers to enter a PK-12 classroom with the knowledge, skills, experiences, and resulting self-efficacy to implement technology-integrated instruction, they must have experienced modeling from teacher preparation faculty and a course of study with relevant experiences (Zhao, 2007). This chapter examines four components of effective technology-integrated, learner-centered instruction as well as the influential role of teacher preparation programs in providing a model and experiences for teacher candidates.