scholarly journals Correction of postkeratoplastic astigmatism by intrastromal corneal segments implantation using a femtosecond laser

2021 ◽  
Vol 6 (6-1) ◽  
pp. 48-55
Author(s):  
N. A. Pozdeyeva ◽  
M. V. Sinitsyn ◽  
A. E. Terentieva ◽  
O. V. Shlenskaya
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Penetrating Keratoplasty ◽  
Biomechanical Properties ◽  
Corneal Graft ◽  
Corneal Resistance Factor ◽  
Astigmatism Correction ◽  
Corrected Visual Acuity ◽  
Uncorrected Visual Acuity ◽  
Best Corrected Visual Acuity

Background. After penetrating keratoplasty, mild to high induced corneal astigmatism was observed in each case. The existing choice of correction of postkeratoplastic astigmatism is aimed at fi nding an individual approach in order to compensate for it and not weaken the biomechanical properties of the corneal graft.The aim: to analyze the clinical, functional, and morphological results of postkeratoplastic astigmatism correction by implantation of intrastromal corneal segments using a femtosecond laser.Methods. 22 patients were examined before and 1 year after surgery. The operation was performed under local anesthesia: stage I – an intrastromal tunnel was formed using a femtosecond laser “Femto Visum” 1 MHz (Optosystems, Russia); stage II – the intrastromal corneal segments were implanted. The results were assessed using standard and special research methods using optical coherence tomography Visante OCT (Zeiss, Germany), keratotopography (Tomey-5, Japan), optical corneal analyzer ORA (Reichert, USA), laser tindalemetry FC-2000 (Kowa, Japan) and confocal microscope Confoscan-4 (Nidek, Japan).Results. Before the operation, uncorrected visual acuity averaged 0.09 ± 0.05, after a year – 0.50 ± 0.16; best corrected visual acuity – 0.30 ± 0.12 and 0.60 ± 0.05 respectively; cylindrical component of refraction – –10.29 ± 3.12 and –2.20 ± 0.64 D respectively; mean keratometry value – 43.59 ± 2.14 and 38.56 ± 1.75 D respectively; corneal hysteresis – 7.92 ± 1.22 and 8.95 ± 1.05 mm Hg respectively; corneal resistance factor – 7.01 ± 1.81 and 8.44 ± 1.44 mm Hg respectively; protein fl ux in the moisture of the anterior chamber – 2.97 ± 0.28 and 3.04 ± 0.24 f/ms respectively; endothelial cell density – 1521 ± 327 and 1475 ± 419 cells/mm2 respectively.Conclusion. Intrastromal corneal segments implantation into a corneal graft using a femtosecond laser has efficiency and safety method in correcting postkeratoplastic astigmatism.

scholarly journals PRELIMINARY CLINICAL AND FUNCTIONAL RESULTS OF ASTIGMATISM CORRECTION AFTER PENETRATING KERATOPLASTY BY THE METHOD OF THE INTRASTROMAL CORNEAL SEGMENTS IMPLANTATION WITH THE APPLICATION OF A FEMTOSECOND LASER

2020 ◽  
Vol 76 (4) ◽  
pp. 169-172
Author(s):  
N.A. Pozdeeva ◽  
◽  
I.L. Kulikova ◽  
A.E. Terentyev ◽  
M.V. Sinitsyn ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Penetrating Keratoplasty ◽  
Functional Results ◽  
Corneal Graft ◽  
Astigmatism Correction

The article presents an analysis of the clinical and functional results of astigmatism correction in 12 patients after penetrating keratoplasty by implantation of intrastromal corneal segments using a femtosecond laser. High refractive efficiency (increased visual acuity, flattening and increased regularity of the corneal graft) and safety in the correction of induced postkeratoplastic astigmatism were noted six months after the operation.

scholarly journals Corneal Neovascularization and Lipid Keratopathy after Intacs SK in Keratoconus

2013 ◽  
Vol 2 (3) ◽  
pp. 133-138
Author(s):  
Ramez Barbara ◽  
David Zadok ◽  
Adel Barbara ◽  
Shay Gutfreund
Keyword(s):  
Visual Acuity ◽  
Penetrating Keratoplasty ◽  
Corneal Neovascularization ◽  
Young Female ◽  
Spherical Equivalent ◽  
Corrected Visual Acuity ◽  
Optical Zone ◽  
Positive Results ◽  
Oval Shape ◽  
Best Corrected Visual Acuity

ABSTRACT Intacs have yielded positive results for the treatment of keratoconus in terms of reducing the keratometry readings astigmatism and spherical equivalent and consequently improving the uncorrected and best corrected visual acuity. Intacs severe keratoconus (SK) are new design of Intacs with a smaller optical zone (6 mm) and oval shape, they are indicated for severe keratocnus. Pannus is one of the complications of Intacs, as it has never been reported after Intacs SK. We report on corneal neovascularization in the corneal periphery which developed few months after Intacs SK implantation in the cornea of a young female who suffered from advanced keratoconus. The uncorrected visual (UCVA) acuity was satisfactory and the Intacs SK where not removed. Four years after the implantation she presented to our clinic complaining about eye irritation and photophobia, lipid keratopathy was observed. We gave here the choice of explanting the Intacs SK or to try to treat the neovascularization by subconjunctival Avastin, she preferred the second option because of a satisfactory UCVA (0.9). Avastin was injected in the subconjunctival, 10 weeks later Avastin and Kenelog were injected in the subconjunctival, few days after the second injection perforation and melting developed in the cornea, the patient underwent a tectonic graft and few months later penetrating keratoplasty with no intraoperative or postoperative complications. How to cite this article Barbara A, Zadok D, Gutfreund S, Barbara R. Corneal Neovascularization and Lipid Keratopathy after Intacs SK in Keratoconus. J Kerat Ect Cor Dis 2013;2(3):133-138.

Femtosecond laser-assisted deep anterior lamellar keratoplasty: A safer option in keratoconus surgery

2021 ◽  
pp. 112067212110590
Author(s):  
Cristina Monterosso ◽  
Marco Antonini ◽  
Antonio Di Zazzo ◽  
Daniele Gaudenzi ◽  
Luigi Caretti ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Lamellar Keratoplasty ◽  
Deep Anterior Lamellar Keratoplasty ◽  
Persistent Epithelial Defect ◽  
Corrected Visual Acuity ◽  
Anterior Lamellar Keratoplasty ◽  
Best Corrected Visual Acuity ◽  
Persistent Epithelial Defects

Purpose To evaluate postoperative safety of femtosecond laser deep anterior lamellar keratoplasty performed with an innovative anvil profile in keratoconus patients. Methods This is a single-center, retrospective cohort study. We reviewed medical records of 89 keratoconus patients that underwent femtosecond laser deep anterior lamellar keratoplasty surgery (46 eyes) and manual deep anterior lamellar keratoplasty (47 eyes). Inclusion criteria required: age > 18 years old, best-corrected visual acuity < 0.3 LogMAR, continuous suture of the graft, postoperative immunomodulant regimen with dexamethasone 0.1% for 6 months and at least 12 months follow-up. Previous eye surgery, hydrops, and other ocular disease were excluded. The main outcome measures were postoperative events: rejections, persistent epithelial defects, and graft failures. Results During the follow-up (20 ± 6 months) graft rejection was diagnosed in 0 of femtosecond laser deep anterior lamellar keratoplasty versus 6 (17%) of manual deep anterior lamellar keratoplasty [ p 0.027], persistent epithelial defect in 0 of femtosecond laser deep anterior lamellar keratoplasty versus in 4 (11%) of manual deep anterior lamellar keratoplasty [ p 0.048] and graft failure occurred in 4 (11%) of manual deep anterior lamellar keratoplasty. The best-corrected visual acuity, after removal of sutures, was better in the femtosecond laser deep anterior lamellar keratoplasty group 0.09 ± 0.08 LogMAR versus 0.16 ± 0.13 LogMAR in manual deep anterior lamellar keratoplasty [ p 0.035] group although refractive spherical equivalent and cylinder, topographic average keratometry and cylinder were similar. Conclusions Anvil-shaped femtosecond laser deep anterior lamellar keratoplasty in keratoconus surgery increases safety and readiness of recovery, decreasing the incidence of corneal rejection, epithelial defects, graft failures, and producing better best-corrected visual acuity after removal of sutures.

Systematic review and meta-analysis of femtosecond laser–enabled keratoplasty versus conventional penetrating keratoplasty

2020 ◽  
pp. 112067212091448
Author(s):  
Yang Liu ◽  
Xiaojun Li ◽  
Wenjie Li ◽  
Xudong Jiu ◽  
Mannan Tian
Keyword(s):  
Femtosecond Laser ◽  
Graft Rejection ◽  
Graft Failure ◽  
Penetrating Keratoplasty ◽  
Mean Difference ◽  
Spherical Equivalent ◽  
Corrected Visual Acuity ◽  
Standard Mean Difference ◽  
Topographic Astigmatism ◽  
Best Corrected Visual Acuity

Purpose: The aim of this meta-analysis is to compare femtosecond laser–enabled keratoplasty with conventional penetrating keratoplasty regarding postoperative astigmatism, visual functions, graft rejection, graft failure, and complications. Methods: Eligible studies were retrieved from five mainstream electronic databases, including PubMed, Embase, Ovid MEDLINE, Cochrane Library, and ClinicalTrial.gov. Postoperative topographic astigmatism was set as the primary outcome, and best-corrected visual acuity, spherical equivalent, endothelial cell density, graft rejection, graft failure, and complications were chosen as the secondary outcomes. Standard mean difference and risk ratio were the size effects for continuous data and binomial data, respectively. The data were pooled through either the random-effects model or the fixed-effects model based on data heterogeneity. Moreover, subgroup analyses were conducted when the heterogeneity occurred distinctly (I2 > 50%). Results: A total of seven comparative studies were included. The pooled standard mean difference (−0.32, 95% confidence interval: −0.74 to 0.10) showed that femtosecond laser–enabled keratoplasty was not superior over conventional penetrating keratoplasty to decrease postoperative topographic astigmatism (p = 0.14). However, best-corrected visual acuity after femtosecond laser–enabled keratoplasty was significantly better than that after conventional penetrating keratoplasty (p = 0.00, standard mean difference: −0.23, 95% confidence interval: −0.37 to −0.10). Furthermore, endothelial cell density after femtosecond laser–enabled keratoplasty was preserved significantly better (p = 0.03, standard mean difference: 0.63, 95% confidence interval: 0.07–1.20). Moreover, spherical equivalent, graft rejection, graft failure, and complications represented no distinct differences between femtosecond laser–enabled keratoplasty and conventional penetrating keratoplasty (p > 0.05). Conclusion: Femtosecond laser–enabled keratoplasty may not be superior over conventional penetrating keratoplasty in decreasing postoperative topographic astigmatism, but might have advantages to achieve best-corrected visual acuity and endothelial cell density preservation. In addition, the two techniques seem to be comparable regarding spherical equivalent, graft rejection/failure, and complications.

scholarly journals Considerations of Visual Quality in Ocular Surgery as Presented at Dry Eye University

2020 ◽  
Vol 3 ((SP1)) ◽  
pp. e28-e29
Author(s):  
Frank Bowden
Keyword(s):  
Visual Acuity ◽  
Visual Experience ◽  
Visual Quality ◽  
Ocular Surgery ◽  
Optical Efficiency ◽  
Corrected Visual Acuity ◽  
Uncorrected Visual Acuity ◽  
Visual Phenomena ◽  
Visual Disturbances ◽  
Best Corrected Visual Acuity

Visual quality may be described as the visual experience which reflects the optimal optical efficiency of the eye. Patients undergoing ocular surgery expect improvement in visual acuity. Ocular surgeons typically aim to improve best-corrected visual acuity. Refractive surgeons, on the other hand, strive to improve uncorrected visual acuity. It is not uncommon that patients with excellent corrected visual acuity following surgery may be dissatisfied with visual quality which is less than anticipated due to unexpected visual disturbances. These visual phenomena may include ghosting, glare, halos, reduced contrast sensitivity, and visual fluctuation.

Femto Circular Keratotomy to Halt the Progression of Keratoconus I and II

2016 ◽  
Vol 5 (3) ◽  
pp. 109-113
Author(s):  
Jörg H Krumeich ◽  
Nino Hirnschall ◽  
Detlev Breyer ◽  
Florian Laufer
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Statistical Evaluation ◽  
Optical Axis ◽  
Stage I ◽  
Time Points ◽  
Corrected Visual Acuity ◽  
Deep Incision ◽  
Descemet’S Membrane ◽  
Best Corrected Visual Acuity

ABSTRACT Aim To simplify and enhance safety in the generation of a stabilizing intracorneal scar by circular keratotomy (CKT). A femtosecond laser was used to perform individually sized intraparenchymal cuts. Materials and methods As equipped, the Ziemer Z6 femto-second laser cuts a 400-µm-deep incision with a diameter of 7.0 mm around the optical axis. The epithelium, Bowmann's membrane, the internal borders of Descemet's membrane, and the endothelium are not affected. The 3-, 6-, and 12-month postoperative values were compared with the 1-month postoperative keratometric readings and astigmatism. The preoperative best corrected visual acuity (BCVA) with glasses was compared with the values found at the same time points as noted above. Results Statistical evaluation indicated that keratometry within ±1.5D remained in 96.6, 93.1, and 96.6% of cases at the 3-, 6-, and 12-month time points respectively. Astigmatism was stable at the same time points in 100, 95.8, and 92.3%. The BCVA improved in 12 cases throughout the first post-operative year (48%, n = 25); however, 11 cases did not change (44%) and 2 cases lost at least one line (8.0%). Conclusion Femto CKT halts the progression of keratoconus for at least 1 year in 96.6% of cases. This treatment provides keratometric and refractive stability for over 1 year. This result, in conjunction with the significant improvement in BCVA, demonstrates the potential of this method for patients with stage I and II keratoconus. How to cite this article Krumeich JH, Hirnschall N, Breyer D, Laufer F. Femto Circular Keratotomy to Halt the Progression of Keratoconus I and II. Int J Kerat Ect Cor Dis 2016;5(3):109-113.

scholarly journals Penetrating Keratoplasty for Keratoconus in Vietnamese Patients

2019 ◽  
Vol 7 (24) ◽  
pp. 4287-4291
Author(s):  
Le Xuan Cung ◽  
Duong Mai Nga ◽  
Nguyen Dinh Ngan ◽  
Nguyen Xuan Hiep ◽  
Do Quyet ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Penetrating Keratoplasty ◽  
Contact Lenses ◽  
High Rate ◽  
Posterior Subcapsular Cataract ◽  
Corrected Visual Acuity ◽  
Severe Stage ◽  
Hard Contact ◽  
Best Corrected Visual Acuity ◽  
Corneal Disorder

BACKGROUND: Keratoconus is an ectatic corneal disorder that can impair the visual acuity. Up to now, penetrating keratoplasty (PK) remains the most common surgical procedure to treat severe keratoconus. In Vietnam, most keratoconus patients come to visit doctor at severe stage and were treated by PK, so we conduct this study. AIM: To evaluate the results of PK for keratoconus in Vietnamese patients. METHODS: This was a retrospective study of 31 eyes with keratoconus who underwent PK in VNIO from January 2005 to December 2014. RESULTS: The average visual acuity was 0.86 ± 0.37 logMAR (20/145). In the group of patients without amblyopia, best spectacle-corrected visual acuity of 20/60 or better was recorded in 75.9% of eyes and 93.1% of eyes achieved a best corrected visual acuity with hard contact lenses of 20/40 or better. Mean postoperative corneal power was 43.8 ± 4.5D. Mean corneal astigmatism was 5.9 ± 2.7D. 94.6% of grafts remained clear. Posterior subcapsular cataract developed in 22.6% of eyes. Graft rejection was recognized in 12.9% of eyes. CONCLUSION: PK is an effective procedure with high rate of graft survival for keratoconus patients. However, patients should be aware of the necessary of optical correction to gain the best VA after surgery.

scholarly journals Explantation and Rotation of Intracorneal Ring Segments with the Support of Femtosecond Laser: An Asymmetrical Version

2013 ◽  
Vol 2 (1) ◽  
pp. 40-42
Author(s):  
E Levinger ◽  
S Levinger ◽  
A Hirsh
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Lower Segment ◽  
Medical Optics ◽  
Corrected Visual Acuity ◽  
Body Sensation ◽  
Uncorrected Visual Acuity ◽  
The Right ◽  
Visual Results

ABSTRACT Purpose To report a 25-year-old man who presented with advance keratoconus in the right eye with uncorrected visual acuity (UCVA) of 0.2 and best spectacle-corrected visual acuity (BSCVA) of 0.33 with +0.50 −9.25 × 45°. Materials and methods Clinical examination and corneal topography revealed grade III keratoconus in the right eye. Intracorneal ring segments (INTACS SK; Addition Technology, Des Plaines, IL) were implanted without surgical complications at 400 µm, with the 450 µm segments implanted superiorly and inferiorly using the femtosecond laser (Intralase®, Advanced Medical Optics, Inc, Abbott Park, IL). Results For 3 months postoperatively, BSCVA remained at 0.5 with plano −4.50 × 25°. The patient was complaining of foreign body sensation in the upper part of the eye and glare asking the surgeon to remove the two segments. The superior segment was removed and the lower segment was rotated 30° counter clockwise. Three months later, UCVA was 0.67 and remained stable for 24 months of follow-up. Conclusion This report shows that implanting the thicker segment inferiorly provides better visual results. How to cite this article Levinger E, Levinger S, Hirsh A. Explantation and Rotation of Intracorneal Ring Segments with the Support of Femtosecond Laser: An Asymmetrical Version. Int J Kerat Ect Cor Dis 2013;2(1):40-42.

scholarly journals Effects of V4c-ICL Implantation on Myopic Patients’ Vision-Related Daily Activities

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Taixiang Liu ◽  
Shaorong Linghu ◽  
Le Pan ◽  
Rong Shi
Keyword(s):  
Visual Acuity ◽  
Daily Activities ◽  
Central Hole ◽  
Spherical Equivalent ◽  
Implantable Collamer Lens ◽  
Corrected Visual Acuity ◽  
Uncorrected Visual Acuity ◽  
New Type ◽  
Best Corrected Visual Acuity ◽  
Better Than

The new type implantable Collamer lens with a central hole (V4c-ICL) is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities. This retrospective study included 42 patients. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), endothelial cell density (ECD), and vault were recorded and vision-related daily activities were evaluated at 3 months after operation. The average spherical equivalent was-0.12±0.33 D at 3 months after operation. UCVA equal to or better than preoperative BCVA occurred in 98% of eyes. The average BCVA at 3 months after operation was-0.03±0.07LogMAR, which was significantly better than preoperative BCVA (0.08±0.10LogMAR) (P=0.029). Apart from one patient (2.4%) who had difficulty reading computer screens, all patients had satisfactory or very satisfactory results. During the early postoperation, halos occurred in 23 patients (54.8%). However there were no significant differences in the scores of visual functions between patients with and without halos (P>0.05). Patients were very satisfied with their vision-related daily activities at 3 months after operation. The central hole of V4c-ICL does not affect patients’ vision-related daily activities.

scholarly journals Ferrara Intrastromal Corneal Ring Segments

2016 ◽  
Vol 5 (3) ◽  
pp. 114-127 ◽  
Author(s):  
Leonardo Torquetti ◽  
Jordana Sandes
Keyword(s):  
Visual Acuity ◽  
Clinical Experience ◽  
Contact Lens ◽  
Corrected Visual Acuity ◽  
Intrastromal Corneal Ring ◽  
Uncorrected Visual Acuity ◽  
Best Corrected Visual Acuity

ABSTRACT The Ferrara intrastromal corneal ring segments (ICRS) are designed to treat ectatic corneal disorders, especially keratoconus. They have been used to reshape keratoconic corneas to improve uncorrected visual acuity, best-corrected visual acuity, contact lens tolerance and to delay or prevent the need for keratoplasty. Intrastromal corneal ring segments have several distinct and important advantages. The Ferrara ICRS have been used largely in several countries for the treatment of primary and secondary ectatic corneal disorders. This article reviews the latest data published and the clinical experience/findings on the treatment of keratoconus by the Ferrara ICRS implantation. How to cite this article Torquetti L, Sandes J, Ferrara G, Ferrara P. Ferrara Intrastromal Corneal Ring Segments. Int J Kerat Ect Cor Dis 2016;5(3):114-127.

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