Basic Concept of Ophthalmology and Visual Disorder

The eye is a complex sensory organ that is responsible for vision. Within the protective sheath, each eye has receptors, a lens system for focusing light on receptors, and a nervous system for transmitting impulses from the receptors to the brain. Visual dysfunction can be caused by abnormal eye movements or changes in visual acuity, refraction, color vision, or accommodation. Visual dysfunction may also be a secondary effect of other neurological disorders. This narrative review aims to describe the structure of the eye in general and visual disturbances caused by the aging process and disorders of the protective structure of the eye.

Foster Kennedy Syndrome: A Case Report

Foster Kennedy Syndrome is a classic, yet rare, neuro-ophthalmologic syndrome due to an intracranial mass, most often a tumor, that consists of optic atrophy on the same side of the lesion and contralateral papilledema. We present the case of a 48-year-old female patient with decreased visual acuity and the typical clinical features described above due to a sphenoid wing meningioma. Although not a common condition, Foster Kennedy Syndrome should always be kept in mind in a patient with visual disturbances secondary to an intracranial mass.

Review on Antifungal Agents

There are so many type of daisies are founded because of ‘Fungal’ such daisies given in follow. also the treatment on this particular daisies with the help of ‘Anti-fungal’ drug or anti- fungal agent and anti-fungal medication as follows The four main classes of antifungal drugs are the polyenes, Azoles, allylamines and echinocandins. Clinically useful “older” agents include topical azole Formulations (for superficial yeast and dermatophyte Infections), first-generation triazoles (fluconazole and Itraconazole, for a range of superficial and invasive fungal Infections), amphotericin B formulations (for a broad range of Invasive fungal infections) and terbinafine (for dermatophyte Infections). Clinically important “newer” agents include members of the Echinocandin class (eg, caspofungin) and second-generation Triazoles (eg, voriconazole and posaconazole). Voriconazole and posaconazole have broad-spectrum activity Against yeasts and moulds, including Aspergillus species. Posaconazole is the only azole drug with activity against Zygomycete fungi. Caspofungin and the other echinocandins are effective in Treating Candida and Aspergillus infections. The azoles are relatively safe, but clinicians should be aware of drug–drug interactions and adverse effects, including Visual disturbances (with voriconazole), elevations in liver Transaminase levels, and skin rashes. Caspofungin has Minimal adverse effects. Combination antifungal therapy may be appropriate in Selected patients with invasive fungal infections, but is Empiric and driven by individual physician practice. Clinical needs for novel antifungal agents have altered

Promotif dan Preventif Bagi Klien Diabetes di Puskesmas Cipto Mulyo Malang terhadap Resiko Kecelakaan Dalam Berkendaraan

DM clients will continue to carry out daily activities like normal people in general, including driving activities. The most trips made by DM patients are to work, fill spare time, recreation and health services. However, there are dangers that can cause accidental diabetic clients, including blood glucose disorders, decreased visual acuity and neuropathy. The risk of accidents for diabetic clients is high. The purpose of this service is that this activity is expected to be able to increase understanding for diabetic clients and prevent the risk of accidents for DM clients. The sampling technique in this service uses purposive sampling. Diabetic clients who participate in this service generally experience problems in driving. The perceived disturbances include frequent fatigue, visual disturbances, decreased response, hyperglycemia and hypoglycemia. It is necessary to have periodic checks in collaboration with the puskesmas regarding this matter. Thus, diabetic clients who are still actively driving are prevented from having accidents.

Integration of proprioceptive and visual feedback during online control of reaching

Visual and proprioceptive feedback both contribute to perceptual decisions, but it remains unknown how these feedback signals are integrated together or consider factors such as delays and variance during online control. We investigated this question by having participants reach to a target with randomly applied mechanical and/or visual disturbances. We observed that the presence of visual feedback during a mechanical disturbance did not increase the size of the muscle response significantly but did decrease variance, consistent with a dynamic Bayesian integration model. In a control experiment we verified that vision had a potent influence when mechanical and visual disturbances were both present but opposite in sign. These results highlight a complex process for multi-sensory integration, where visual feedback has a relatively modest influence when the limb is mechanically disturbed, but a substantial influence when visual feedback becomes misaligned with the limb.

Postural regulation of teenagers performing pop dance, according to stabilometry data

Knowledge of postural regulation in different sports is useful for sports selection and for improvement of postural stereotypes.Objective: to reveal postural regulation features of teenagers involved in pop dance.Materials and methods: 15 pop dancers involved in dance more than 10 years performed Romberg and optokinetic tests on computer stabilograph “Trust-M Stabilo”.Results: the area and length of the dancers’ statokinesiogram were less than in general sample, statokinesiogram’s pressure center had been dextrally dislocated. Visual disturbances as well as vision deprivation led to statistically significant increase in speed of center of pressure movement along reference plane and in the ratio of statokinesiogram’s length to its area. All these changes were less pronounced than in the general sample.Conclusions: postural regulation of dancers proved to be better than that of healthy people who were not involved in sports.

Giant cell arteritis: a case report with scalp necrosis and sudden blindness

In the summer of 2020, an elderly woman in her eighties sought medical attention due to headache and visual disturbances. The diagnosis was unclear, she became blind on both eyes and developed extended scalp necrosis. Later it was clear that these symptoms were due to accelerating symptoms of giant cell arteritis (GCA). GCA is one of the most common disease form of vasculitis and can have various symptoms. In this report, we describe a case of an advanced disease course, discuss the main symptoms, diagnosis and treatment.

Neurological manifestation of Vitamin D deficiency

Idiopathic intracranial hypertension, also known as pseudotumor cerebri, is a disorder with raised intracranial pressure, headache, papilledema, visual disturbances with a normal cerebrospinal fluid examination, and normal neuroimaging. It is rare in the pediatric population and may occur as a manifestation of underlying disorders. Vitamin D deficiency is a common deficiency in the pediatric age group. However, neurological manifestations are rare. Here, we present the case of a 5-year-old male child who presented with headache, vomiting, and hypertension; however, the neurological examination was normal but the neuroimaging was suggestive of pseudotumor cerebri. Appropriate investigations were done. The most likely cause of pseudotumor cerebri in this patient was the deficiency of Vitamin D. We have reported this case as pseudotumor cerebri is a rare neurological manifestation of Vitamin D deficiency.

Improving postural stability among people with lower-limb amputations by tactile sensory substitution

Background For people with lower-limb amputations, wearing a prosthetic limb helps restore their motor abilities for daily activities. However, the prosthesis's potential benefits are hindered by limited somatosensory feedback from the affected limb and its prosthesis. Previous studies have examined various sensory substitution systems to alleviate this problem; the prominent approach is to convert foot–ground interaction to tactile stimulations. However, positive outcomes for improving their postural stability are still rare. We hypothesized that the sensory substiution system based on surrogated tactile stimulus is capable of improving the standing stability among people with lower-limb amputations. Methods We designed a wearable device consisting of four pressure sensors and two vibrators and tested it among people with unilateral transtibial amputations (n = 7) and non-disabled participants (n = 8). The real-time measurements of foot pressure were fused into a single representation of foot–ground interaction force, which was encoded by varying vibration intensity of the two vibrators attached to the participants’ forearm. The vibration intensity followed a logarithmic function of the force representation, in keeping with principles of tactile psychophysics. The participants were tested with a classical postural stability task in which visual disturbances perturbed their quiet standing. Results With a brief familiarization of the system, the participants exhibited better postural stability against visual disturbances when switching on sensory substitution than without. The body sway was substantially reduced, as shown in head movements and excursions of the center of pressure. The improvement was present for both groups of participants and was particularly pronounced in more challenging conditions with larger visual disturbances. Conclusions Substituting otherwise missing foot pressure feedback with vibrotactile signals can improve postural stability for people with lower-limb amputations. The design of the mapping between the foot–ground interaction force and the tactile signals is essential for the user to utilize the surrogated tactile signals for postural control, especially for situations that their postural control is challenged.