scholarly journals Microbiological characteristics of early and late infectious complications following total pelvic exenteration due to cervical cancer recurrence—the significance of infections in long-term outcomes

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Sebastian Szubert



2020 ◽  
Vol 18 (1) ◽  
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Krzysztof Koper ◽  
Agnieszka Koper ◽  
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...  


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Vol 11 (3) ◽  
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Tolga Taşçı ◽  
Taner Turan ◽  
Nurettin Boran ◽  
...  


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Daniel Zaidan Santos ◽  
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Vol 89 (6) ◽  
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2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15551-e15551
Author(s):  
Patrizio Damiani ◽  
Francesco Plotti ◽  
Marzio Angelo Zullo ◽  
Carlo De Cicco Nardone ◽  
Roberto Montera ◽  
...  

e15551 Background: The aim of the present study is to describe feasibility, surgical technique, perioperative data, early and late complications of anterior and total pelvic exenteration after neoadjuvant chemotherapy as primary treatment for stage IVa cervical cancer. Methods: It is a retrospective study which included 73 consecutive patients affected by stage IVa cervical cancer who required anterior or total pelvic exenteration referred to 3 international gynaecologic oncology centres. The steps of this extirpative surgical procedure were: 1) staging laparotomy; 2) frozen section biopsy of the paraaortic lymph nodes; 3) systematic lymphadenectomy, radical hysterectomy with adnexectomy and total or anterior pelvic exenteration; 4) continent urinary diversions and low colorectal anastomosis if it was possible. Results: The treatment of patients affected by FIGO stage IVA cervical cancer remains one of the most complex procedures gynecologic oncologists are faced with. Our study focused on clinical and operative data , in terms of overall survival (OS) and disease free survival (DFS) at 5 years. 5-year OS of our series was 43%. Conclusions: The surgical treatment of stage IVA cervical cancer appears therefore a suitable and valid alternative. Stage IVA cervical cancer patients in good general condition, with a disease resectable with clear surgical margins, should be considered for primary exenteration in referral centers where the surgical experience to perform this procedure is available.





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