Urinary calcium oxalate monohydrate crystals in ethylene glycol poisoning

1982 ◽  
Vol 42 (3) ◽  
pp. 231-234 ◽  
Author(s):  
Dag Jacobsen ◽  
Ingvar Åkesson ◽  
Eli Shefterd
2011 ◽  
Vol 341 (4) ◽  
pp. 338 ◽  
Author(s):  
Ashar Luqman ◽  
John Stanifer ◽  
Omer M. Asif Siddiqui ◽  
Adnan Naseer ◽  
Barry M. Wall

1985 ◽  
Vol 22 (6) ◽  
pp. 625-628 ◽  
Author(s):  
M. A. Thrall ◽  
S. M. Dial ◽  
D. R. Winder

Urine sediments of dogs with experimentally induced ethylene glycol poisoning were examined by light microscopy and X-ray diffraction. Massive calcium oxalate crystalluria was observed in all poisoned dogs. By light microscopy, the frequency with which six-sided hippurate-like prisms and envelope forms of calcium oxalate dihydrate occurred was approximately equal. The hippurate-like crystals were shown to be calcium oxalate monohydrate by X-ray diffractometry.


1980 ◽  
Vol 16 (4) ◽  
pp. 479-486 ◽  
Author(s):  
W. Godolphin ◽  
E. P. Meagher ◽  
H. D. Sanders ◽  
J. Frohlich

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Felix Grases ◽  
Rafel M. Prieto ◽  
Rafel A. Fernandez-Cabot ◽  
Antonia Costa-Bauzá ◽  
Fernando Tur ◽  
...  

Nephrolithiasis is a complex disease that results from a combination of factors related to both urine composition and kidney morphoanatomy. Development of calcium oxalate monohydrate papillary calculi is linked to initial subepithelial calcification of renal papilla. Progressive tissue calcification depends on preexisting injury and involves reactive oxygen species. Many plant extracts that protect against oxidative stress manifest antilithiasic activity. Our study focused on determining the effects of polyphenols on a lithiasis rat model. Rats were pretreated with polyphenols and grape seed extracts, followed by posterior induction of hyperoxalosis via treatment with ethylene glycol plus NH4Cl. The concentrations of calcium and other elements in kidney were determined, along with histological examination of kidney and 24 h urine analysis. Significant differences were observed in the renal calcium content between the control plus ethylene glycol-treated group and the epicatechin plus ethylene glycol-treated, red grape seed extract plus ethylene glycol-treated, and white grape seed extract plus ethylene glycol-treated groups, with reductions of about 50%. The antioxidant activity of polyphenols extracted from red and white grape seeds may be critical in the prevention of calcium oxalate monohydrate papillary calculus formation, particularly if calculi are induced by lesions caused by cytotoxic compounds with oxidative capacity.


2020 ◽  
Vol 10 (2) ◽  
pp. 5028-5031

The present review was performed to gather the available literature on the nephroprotective effects of catechins against toxic agents. Several studies have demonstrated the therapeutic effects of catechins versus nephrotoxic agents such as cisplatin, cyclosporine A, tamoxifen, FK506, gentamicin, ethylene glycol, calcium, oxalate monohydrate, cadmium, ferric nitrilotriacetate, hydrogen peroxide, contrast medium, fructose, glucose, melamine vanadium, ochratoxin A, streptozotocin. However, more investigations should be done to indicate the nephroprotective effects of catechins against toxic agents in humans.


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