Short-Chain Fatty Acids in the Small-Bowel Bacterial Overgrowth Syndrome

1985 ◽  
Vol 20 (4) ◽  
pp. 492-499 ◽  
Author(s):  
T. Hosverstad ◽  
A. Bjosrneklett ◽  
O. Fausa ◽  
T. Midtvedt
Keyword(s):  
Fatty Acids ◽  
Small Bowel ◽  
Bacterial Overgrowth ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Small Bowel Bacterial Overgrowth ◽  
Overgrowth Syndrome ◽  
Chain Fatty Acids

scholarly journals Glutamine alone or combined with short-chain fatty acids fails to enhance gut adaptation after massive enterectomy in rats

2006 ◽  
Vol 21 (suppl 4) ◽  
pp. 2-7 ◽  
Author(s):  
José de Souza Neves ◽  
José Eduardo de Aguilar-Nascimento ◽  
Maria Helena Gaiva Gomes-da-Silva ◽  
Rosecélia Nunes Cavalcanti ◽  
Alberto Salomão Bicudo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Small Bowel ◽  
Intestinal Adaptation ◽  
Short Chain Fatty Acids ◽  
Small Bowel Resection ◽  
Short Chain ◽  
Control Group ◽  
Wall Width ◽  
Morphological Findings ◽  
Chain Fatty Acids

PURPOSE: To investigate the effect of oral glutamine alone or combined with short chain fatty acids (SCFA) in the intestinal adaptation of rats submitted to an massive enterectomy. METHODS: After receiving 70% small bowel resection, 30 Wistar rats were randomized to received either standard rat chow (control group, n=10) or the same diet supplemented with 3,05% of glutamine alone (glutamine group, n=10) or combined with a solution containing SCFA (glutamine+SCFA group, n=10). Animals were killed on the 14th postoperative day. Mucosal weight, crypt depth, villus height, wall width, and the mucosal content of DNA, were assessed in basal conditions (resected gut specimen) and compared to the small bowel specimen collected on the postoperative day 14, at both jejunum and ileum sites. RESULTS: All groups presented similar pattern in weight evolution. In all groups, both the morphological findings and the DNA content were significantly higher at the end of the experiment than in basal conditions, at both the jejunum and ileum. Except for the jejunum wall width that was higher in control group (808±95 µ) than in the other two groups (glutamine = 649±88 µ and glutamine+SCFA = 656±92; p<0.01), there was no difference among them in all variables at both intestinal sites after 14 days. CONCLUSION: All groups presented adaptation of the intestinal mucosa in the remnant gut. Glutamine combined or not with short chain fatty acids fails to influence the adaptive response of the small bowel.

scholarly journals Intraluminal injection of short chain fatty acids diminishes intestinal mucosa injury in experimental ischemia-reperfusion

2006 ◽  
Vol 21 (1) ◽  
pp. 21-25 ◽  
Author(s):  
José Eduardo de Aguilar-Nascimento ◽  
Alberto Bicudo Salomão ◽  
Rubens Jardim Nochi Jr. ◽  
Mariana Nascimento ◽  
José de Souza Neves
Keyword(s):  
Fatty Acids ◽  
Small Bowel ◽  
Intestinal Mucosa ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Mucosal Injury ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Small Bowel Mucosa ◽  
Chain Fatty Acids

PURPOSE: Investigated the effect of intraluminal short-chain fatty acids (SCFA) on the intestinal mucosa in the presence of ischemia-reperfusion injury (IRI). METHODS: Six blind sacs of the small bowel (3at the jejunum and 3 at the ileum) were created in ten Wistar rats. The lateral sacs of both bowel regions were subjected to IRI (15/15 minutes) while the medial sacs were let free to receive blood supply. In the lateral sacs, it was injected either a solution containing SCFA (butyrate, propionate and acetate) or pure saline at the bowel lumen. No fluid was injected in the medial sacs. RESULTS: Both at the jejunum and at the ileum the score of the mucosal injury was higher in saline than in control sacs. SCFA treated sacs showed lesser score at the ileum (p=0.03) but were not significantly different at the jejunum (p=0.83) when compared with saline sacs. It was found a significant greater number of neutrophils (p < 0.01) in the sacs treated with saline than in the other two sacs in both regions. CONCLUSION: SCFA protect the distal small bowel mucosa and diminishes infiltration of neutrophils to the gut lamina propria in IRI.

Parenteral nutrition supplemented with short-chain fatty acids: effect on the small-bowel mucosa in normal rats

1990 ◽  
Vol 51 (4) ◽  
pp. 685-689 ◽  
Author(s):  
M J Koruda ◽  
R H Rolandelli ◽  
D Z Bliss ◽  
J Hastings ◽  
J L Rombeau ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Small Bowel ◽  
Parenteral Nutrition ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Small Bowel Mucosa ◽  
Bowel Mucosa ◽  
Chain Fatty Acids

Effect of short-chain fatty acids on the ethylene pathway in embryonic axes of Cicer arietinum during germination

1994 ◽  
Vol 92 (4) ◽  
pp. 629-635 ◽  
Author(s):  
Mercedes Gallardo ◽  
Paloma Munoz De Rueda ◽  
Angel Jesus Matilla ◽  
Isabel Maria Sanchez-Calle
Keyword(s):  
Fatty Acids ◽  
Cicer Arietinum ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Embryonic Axes ◽  
Chain Fatty Acids

Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 92-OR ◽  
Author(s):  
WEI HUANG ◽  
YONG XU ◽  
YOUHUA XU ◽  
LUPING ZHOU ◽  
CHENLIN GAO
Keyword(s):  
Fatty Acids ◽  
Diabetic Nephropathy ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

1898-P: Colonic Short-Chain Fatty Acids Lower Endogenous Glucose Production

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1898-P
Author(s):  
ADELINA I.L. LANE ◽  
SAVANNA N. WENINGER ◽  
FRANK DUCA
Keyword(s):  
Fatty Acids ◽  
Glucose Production ◽  
Short Chain Fatty Acids ◽  
Endogenous Glucose Production ◽  
Short Chain ◽  
Endogenous Glucose ◽  
Chain Fatty Acids

Concentrations and Correlations of Faecal Short-chain Fatty Acids and Faecal Water Content in Man

1994 ◽  
Vol 7 (6) ◽  
Author(s):  
U. Siigur ◽  
K. E. Norin ◽  
G. Allgood ◽  
T. Schlagheck ◽  
Tore Midtvedt
Keyword(s):  
Fatty Acids ◽  
Water Content ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids
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