Papillary thyroid carcinoma arising from mature cystic teratoma of the ovary

2010 ◽  
Vol 30 (8) ◽  
pp. 884-886 ◽  
Author(s):  
I. Lataifeh ◽  
M. Abdel-Hadi ◽  
B. Morcos ◽  
M. Sughayer ◽  
S. Barahmeh
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Papillary Thyroid

scholarly journals Carcinoid tumor and papillary thyroid carcinoma arising from ovarian mature cystic teratoma: two cases of an extraordinary malignant transformation

2021 ◽  
Vol 10 (4) ◽  
pp. 1686
Author(s):  
Jimmy A. Billod ◽  
Joella G. Saure ◽  
Katrina Mae A. Natavio
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Dermoid Cyst ◽  
Malignant Transformation ◽  
Carcinoid Tumor ◽  
Cystic Teratoma ◽  
Immunohistochemical Analysis ◽  
Mature Cystic Teratoma ◽  
Papillary Thyroid ◽  
Complete Excision

The most common malignant transformation of mature cystic teratoma of the ovary (MCTO) is squamous cell carcinoma, whereas, carcinoid tumor and papillary thyroid carcinoma are extremely extraordinary. This paper presents two rare cases of malignant transformation from MCTO. First, in a 33 year old, nulligravid, who underwent oophorocystectomy for a dermoid cyst. Histopathologic and Immunohistochemical studies revealed a carcinoid tumor arising from a mature cystic teratoma. Second, in a 52 year old who underwent, total abdominal hysterectomy with bilateral salpingo-oophorectomy for an ovarian new growth, with a final histopathologic and immunohistochemical analysis showed follicular variant of papillary carcinoma arising from mature cystic teratoma. Preoperative diagnosis of MCTO can be made through physical examination and imaging however not the concealed malignancy. Thorough extensive sampling and histopathologic examination of a dermoid cyst is necessary to detect malignant transformation. The optimal management of the disease is uncertain because of its rarity, but complete excision of tumor renders excellent prognosis.

scholarly journals Papillary thyroid carcinoma arising within a mature cystic teratoma of ovary: a rare case report

2020 ◽  
Vol 7 (3) ◽  
pp. 80-83
Author(s):  
Surendra Prasad Bhatta ◽  
Sarada Duwal Shrestha
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Rare Case ◽  
Case Reports ◽  
Cystic Teratoma ◽  
Thyroid Function Test ◽  
Thyroid Tumor ◽  
Mature Cystic Teratoma ◽  
Papillary Thyroid ◽  
Thyroglobulin Antibody

Mature cystic teratoma is the most common ovarian germ cell tumor with a rare malignant conversion. We report a case of 36 years lady, with an incidental post-operative finding of papillary carcinoma of the thyroid in histopathology of the left ovarian dermoid cyst. Postoperatively she was evaluated for the presence of primary thyroid tumor with thyroid ultrasonography, thyroid function test, and anti-thyroglobulin antibody which revealed normal thyroid gland with euthyroid status and negative anti-thyroglobulin antibody, which had ruled out primary thyroid tumor. There are limited case reports on papillary thyroid carcinoma in a mature cystic teratoma in absence of a struma ovary and specific recommendations on the plan of its management are not available. This study aims to report a rare case of papillary thyroid carcinoma arising in a mature cystic teratoma of the ovary in absence of a struma ovary.

Papillary Thyroid Carcinoma: How Radical Lymphadenectomy Should be Performed?

Swiss Surgery ◽  
2003 ◽  
Vol 9 (2) ◽  
pp. 63-68
Author(s):  
Schweizer ◽  
Seifert ◽  
Gemsenjäger
Keyword(s):  
High Risk ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Low Risk ◽  
Papillary Thyroid ◽  
Sentinel Nodes ◽  
Fand Sich ◽  
Radical Lymphadenectomy ◽  
N Status

Fragestellung: Die Bedeutung von Lymphknotenbefall bei papillärem Schilddrüsenkarzinom und die optimale Lymphknotenchirurgie werden kontrovers beurteilt. Methodik: Retrospektive Langzeitstudie eines Operateurs (n = 159), prospektive Dokumentation, Nachkontrolle 1-27 (x = 8) Jahre, Untersuchung mit Bezug auf Lymphknotenbefall. Resultate: Staging. Bei 42 Patienten wurde wegen makroskopischem Lymphknotenbefall (cN1) eine therapeutische Lymphadenektomie durchgeführt, mit pN1 Status bei 41 (98%) Patienten. Unter 117 Patienten ohne Anhalt für Lymphknotenbefall (cN0) fand sich okkulter Befall bei 5/29 (17%) Patienten mit elektiver (prophylaktischer) Lymphadenektomie, und bei 2/88 (2.3%) Patienten ohne Lymphadenektomie (metachroner Befall) (p < 0.005). Lymphknotenrezidive traten (1-5 Jahre nach kurativer Primärtherapie) bei 5/42 (12%) pN1 und bei 3/114 (2.6%) cN0, pN0 Tumoren auf (p = 0009). Das 20-Jahres-Überleben war bei TNM I + II (low risk) Patienten 100%, d.h. unabhängig vom N Status; pN1 vs. pN0, cN0 beeinflusste das Überleben ungünstig bei high risk (>= 45-jährige) Patienten (50% vs. 86%; p = 0.03). Diskussion: Der makroskopische intraoperative Lymphknotenbefund (cN) hat Bedeutung: - Befall ist meistens richtig positiv (pN1) und erfordert eine ausreichend radikale, d.h. systematische, kompartiment-orientierte Lymphadenektomie (Mikrodissektion) zur Verhütung von - kurablem oder gefährlichem - Rezidiv. - Okkulter Befall bei unauffälligen Lymphknoten führt selten zum klinischen Rezidiv und beeinflusst das Überleben nicht. Wir empfehlen eine weniger radikale (sampling), nur zentrale prophylaktische Lymphadenektomie, ohne Risiko von chirurgischer Morbidität. Ein empfindlicherer Nachweis von okkultem Befund (Immunhistochemie, Schnellschnitt von sampling Gewebe oder sentinel nodes) erscheint nicht rational. Bei pN0, cN0 Befund kommen Verzicht auf 131I Prophylaxe und eine weniger intensive Nachsorge in Frage.

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