Early Cartilage Degeneration in a Rat Experimental Model of Developmental Dysplasia of the Hip

2012 ◽  
Vol 53 (6) ◽  
pp. 513-520 ◽  
Author(s):  
Ning Bo ◽  
Wang Peng ◽  
Pei Xinghong ◽  
Ruixue Ma
Keyword(s):  
Experimental Model ◽  
Cartilage Degeneration ◽  
Developmental Dysplasia ◽  
Dysplasia Of The Hip

scholarly journals Severe cartilage degeneration in patients with developmental dysplasia of the hip

IUBMB Life ◽  
2017 ◽  
Vol 69 (3) ◽  
pp. 179-187 ◽  
Author(s):  
Wei-Jia Feng ◽  
Hui Wang ◽  
Chao Shen ◽  
Jun-Feng Zhu ◽  
Xiao-Dong Chen
Keyword(s):  
Cartilage Degeneration ◽  
Developmental Dysplasia ◽  
Dysplasia Of The Hip

scholarly journals Prediction of the requirement of open reduction for developmental dysplasia of the hip

2017 ◽  
Vol 46 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Nabil Alassaf
Keyword(s):  
Open Reduction ◽  
Area Under The Curve ◽  
Internal Validity ◽  
Developmental Dysplasia ◽  
Estimation Model ◽  
Cross Sectional ◽  
Noninvasive Treatment ◽  
Dysplasia Of The Hip ◽  
Logistic Regression Equation ◽  
Objective Tool

Objective Closed reduction (CR) is a noninvasive treatment for developmental dysplasia of the hip (DDH), and this treatment is confirmed intraoperatively. This study aimed to develop a preoperative estimation model of the probability of requiring open reduction (OR) for DDH. Methods The study design was cross-sectional by screening all patients younger than 2 years who had attempted CR between October 2012 and July 2016 by a single surgeon. Potential diagnostic determinants were sex, age, side, bilaterality, International Hip Dysplasia Institute (IHDI) grade, and acetabular index (AI). An intraoperative arthrogram was the reference standard. A logistic regression equation was built from a reduced model. Bootstrapping was performed for internal validity. Results A total of 164 hips in 104 patients who met the inclusion criteria were analysed. The prevalence of CR was 72.2%. Independent factors for OR were older age, higher IHDI grade, and lower AI. The probability of OR = 1/[1 + exp − (−2.753 + 0.112 × age (months) + 1.965 × IHDI grade III (0 or 1) + 3.515 × IHDI grade IV (0 or 1) − 0.058 × AI (degrees)]. The area under the curve was 0.79. Conclusion This equation is an objective tool that can be used to estimate the requirement for OR.

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