scholarly journals Drug metabolism and disposition: recent advances in regulation, structure function, and pharmacogenomics of UDP-glucuronosyltransferasesGuest editor: Anna Radominska-Pandya

2009 ◽  
Vol 42 (1) ◽  
pp. i-iii
Keyword(s):  
Drug Metabolism ◽  
Structure Function ◽  
Recent Advances

Considerations and recent advances in QSAR models for cytochrome P450-mediated drug metabolism prediction

2008 ◽  
Vol 22 (11) ◽  
pp. 843-855 ◽  
Author(s):  
Haiyan Li ◽  
Jin Sun ◽  
Xiaowen Fan ◽  
Xiaofan Sui ◽  
Lan Zhang ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Recent Advances ◽  
Qsar Models ◽  
Drug Metabolism Prediction

Recent Advances in Membrane Biochemistry

2011 ◽  
Vol 39 (3) ◽  
pp. 703-706 ◽  
Author(s):  
J. Malcolm East ◽  
Francesco Michelangeli
Keyword(s):  
Membrane Protein ◽  
Structure Function ◽  
Human Health ◽  
Membrane Structure ◽  
Protein Structures ◽  
Annual Symposium ◽  
Recent Advances ◽  
Society Annual

This Biochemical Society Annual Symposium on Recent Advances in Membrane Biochemistry was organized to bring together experts from across the spectrum of biomembrane disciplines from the biological to the biophysical/structural, with the intention of promoting interactions and collaborations across the field. We were keen that the potential for improving human health that stems from a deeper understanding of membrane structure/function should be acknowledged, especially in the light of the increasing numbers of membrane protein structures that continue to be made available to the biomembrane community. This foreword provides an idea of what was communicated in the various sessions and, we hope, gives an impression of the excitement generated by the speakers and delegates at this over-subscribed Symposium.

scholarly journals Cytochrome P450 enzymes: understanding the biochemical hieroglyphs

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 178 ◽  
Author(s):  
John T. Groves
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Reactive Intermediates ◽  
Heme Iron ◽  
Cytochrome P450 Enzymes ◽  
Steroid Biosynthesis ◽  
Reaction Cycle ◽  
Cyp Enzymes ◽  
Protein Architecture ◽  
Recent Advances

Cytochrome P450 (CYP) enzymes are the primary proteins of drug metabolism and steroid biosynthesis. These crucial proteins have long been known to harbor a cysteine thiolate bound to the heme iron. Recent advances in the field have illuminated the nature of reactive intermediates in the reaction cycle. Similar intermediates have been observed and characterized in novel heme-thiolate proteins of fungal origin. Insights from these discoveries have begun to solve the riddle of how enzyme biocatalyst design can afford a protein that can transform substrates that are more difficult to oxidize than the surrounding protein architecture.

Recent advances in TMEM16A: Structure, function, and disease

2018 ◽  
Vol 234 (6) ◽  
pp. 7856-7873 ◽  
Author(s):  
Qiushuang Ji ◽  
Shuai Guo ◽  
Xuzhao Wang ◽  
Chunli Pang ◽  
Yong Zhan ◽  
...  
Keyword(s):  
Structure Function ◽  
Recent Advances
Sign in / Sign up

Export Citation Format

Share Document