Influence of the inlet air temperature in a fluid bed coating process on drug release from shellac-coated pellets

2010 ◽  
Vol 37 (3) ◽  
pp. 320-328 ◽  
Author(s):  
Yassin Farag ◽  
Claudia Sabine Leopold
Keyword(s):  
Drug Release ◽  
Air Temperature ◽  
Coating Process ◽  
Fluid Bed ◽  
Fluid Bed Coating

scholarly journals Quality-by-Design approach to the fluid-bed coating of ginkgo lactone nanosuspensions

RSC Advances ◽  
2018 ◽  
Vol 8 (39) ◽  
pp. 22136-22145
Author(s):  
Jiawei Han ◽  
Xin Wang ◽  
Jingxian Wang ◽  
Lingchong Wang ◽  
Lihua Chen ◽  
...  
Keyword(s):  
Quality By Design ◽  
Design Approach ◽  
Coating Process ◽  
Fluid Bed ◽  
Quality By Design Approach ◽  
Fluid Bed Coating

The Quality-by-Design (QbD) approach was employed to investigate the fluid-bed coating process for the conversion of ginkgo lactone (GL) liquid nanosuspensions into dried nanosuspensions.

PAT-Based Control of Fluid Bed Coating Process Using NIR Spectroscopy to Monitor the Cellulose Coating on Pharmaceutical Pellets

2016 ◽  
Vol 18 (6) ◽  
pp. 2045-2054 ◽  
Author(s):  
Venkata Ramana Naidu ◽  
Rucha S. Deshpande ◽  
Moinuddin R. Syed ◽  
Piyush Deoghare ◽  
Dharamvir Singh ◽  
...  
Keyword(s):  
Nir Spectroscopy ◽  
Coating Process ◽  
Fluid Bed ◽  
Fluid Bed Coating

In line NIR quantification of film thickness on pharmaceutical pellets during a fluid bed coating process

2011 ◽  
Vol 403 (1-2) ◽  
pp. 66-72 ◽  
Author(s):  
Min-Jeong Lee ◽  
Da-Young Seo ◽  
Hea-Eun Lee ◽  
In-Chun Wang ◽  
Woo-Sik Kim ◽  
...  
Keyword(s):  
Film Thickness ◽  
Coating Process ◽  
Fluid Bed ◽  
Fluid Bed Coating

scholarly journals Film Coating of Nifedipine Extended Release Pellets in a Fluid Bed Coater with a Wurster Insert

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Luciane Franquelin Gomes de Souza ◽  
Marcello Nitz ◽  
Osvaldir Pereira Taranto
Keyword(s):  
Air Temperature ◽  
Extended Release ◽  
Simulated Gastric Fluid ◽  
Prolonged Release ◽  
Coating Process ◽  
Dissolution Profile ◽  
Lauryl Sulfate ◽  
Drug Content ◽  
Coating Efficiency ◽  
Fluid Bed

The objective of this work was to study the coating process of nifedipine extended release pellets using Opadry and Opadry II, in a fluid bed coater with a Wurster insert. The coating process was studied using a complete experimental design of two factors at two levels for each polymer. The variables studied were the inlet air temperature and the coating suspension flow rate. The agglomerate fraction and coating efficiency were the analyzed response variables. The air temperature was the variable that most influenced the coating efficiency for both polymers. In addition, a study of the dissolution profiles of coated and uncoated pellets using 0.5% sodium lauryl sulfate in simulated gastric fluid without enzymes (pH 1.2) was conducted. The results showed a prolonged release profile for the coated and uncoated pellets that was very similar to the standards established by the U.S. Pharmacopoeia. The drug content and the release profiles were not significantly affected by storage at 40°C and 75% relative humidity. However, when exposed to direct sunlight and fluorescent light (light from fluorescent bulbs), the coated pellets lost only 5% of the drug content, while the uncoated ones lost more than 35%; furthermore, the dissolution profile of the uncoated pellets was faster.

scholarly journals Development and evaluation of diltiazem hydrochloride controlled-release pellets by fluid bed coating process

2013 ◽  
Vol 4 (2) ◽  
pp. 101 ◽  
Author(s):  
Suryadevara Vidyadhara ◽  
Talamanchi Balakrishna ◽  
MikkilineniBhanu Prasad ◽  
Reddyvalam LankapalliC Sasidhar ◽  
Pavuluri Trilochani
Keyword(s):  
Controlled Release ◽  
Coating Process ◽  
Diltiazem Hydrochloride ◽  
Fluid Bed ◽  
Fluid Bed Coating
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