Clinical efficacy and safety of augmented betamethasone dipropionate ointment and diflorasone diacetate ointment for psoriasis — a multicentre, randomized, double-blinded study

1991 ◽  
Vol 2 (2) ◽  
pp. 63-66 ◽  
Author(s):  
Tsu-Yi Chuang ◽  
C. R. Samson
Keyword(s):  
Clinical Efficacy ◽  
Betamethasone Dipropionate ◽  
Efficacy And Safety ◽  
Blinded Study ◽  
Double Blinded

scholarly journals Fentanyl-sparing Effect of Acetaminophen as a Mixture of Fentanyl in Intravenous Parent-/Nurse-controlled Analgesia after Pediatric Ureteroneocystostomy

2010 ◽  
Vol 113 (3) ◽  
pp. 672-677 ◽  
Author(s):  
Jeong-Yeon Hong ◽  
Won Oak Kim ◽  
Bon Nyeo Koo ◽  
Jin Sun Cho ◽  
Eun H. Suk ◽  
...  
Keyword(s):  
Side Effects ◽  
Infusion Rate ◽  
Loading Dose ◽  
Efficacy And Safety ◽  
Pediatric Pain ◽  
Pain Scores ◽  
Blinded Study ◽  
Sparing Effect ◽  
Double Blinded ◽  
Fentanyl Group

Background Although acetaminophen has been used widely and is well tolerated in children, its efficacy and safety have not been clarified when combined with an opioid in intravenous parent-/nurse-controlled postoperative analgesia. Methods Sixty-three children (aged 6-24 months) who had undergone elective ureteroneocystostomies were enrolled in this prospective, randomized, double-blinded study. After the surgery, an analgesic pump was programmed to deliver fentanyl at a basal infusion rate of 0.25 microg.kg(-1).h(-1) and 0.25 microg/kg bolus after a loading dose of 0.5 microg/kg(-1). In the fentanyl-acetaminophen group, acetaminophen was coadministered as a solution mixture at a basal infusion rate of 1.5 mg.kg(-1).h(-1) and 1.5 mg/kg bolus after a loading dose of 15 mg/kg, whereas saline was administered to the fentanyl group. Results Postoperative pain scores were similar between the two groups. The total dose (micrograms per kilogram per day, mean+/-SD) of fentanyl at postoperative days 1 (8.3+/-3.7 vs. 18.1+/-4.6, P=0.021) and 2 (7.0+/-2.4 vs. 16.6, P=0.042) was significantly less in the fentanyl-acetaminophen group compared with that in the fentanyl group. The incidences of vomiting (16.1 vs. 56.3%, P=0.011) and sedation (9.7 vs. 46.9%, P=0.019) were significantly lower in the fentanyl-acetaminophen group than those in the fentanyl group. Conclusions Acetaminophen has significant fentanyl-sparing effects and reduces side effects when combined with fentanyl in intravenous parent-/nurse-controlled analgesia for postoperative pediatric pain management.

The Efficacy and Safety of Guardix-SG® in Patients Who Are Undergoing Thyroid Surgery: A Randomized, Prospective, Double-blinded Study

2009 ◽  
Vol 9 (3) ◽  
pp. 127 ◽  
Author(s):  
Jae Hyun Park ◽  
Jong Ju Jeong ◽  
Sang Wook Kang ◽  
Kee Hyun Nam ◽  
Hang Seok Chang ◽  
...  
Keyword(s):  
Thyroid Surgery ◽  
Efficacy And Safety ◽  
Blinded Study ◽  
Double Blinded

Clinical efficacy and safety of the combination therapy of peginterferon alpha and ribavirin in cirrhotic patients with HCV infection

2010 ◽  
Vol 16 (1) ◽  
pp. 38 ◽  
Author(s):  
Hong Ryeol Cheong ◽  
Hyun Young Woo ◽  
Jeong Heo ◽  
Ki Tae Yoon ◽  
Dong Uk Kim ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Clinical Efficacy ◽  
Hcv Infection ◽  
Efficacy And Safety ◽  
Cirrhotic Patients
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