Pulmonary coagulation and fibrinolysis in acute lung injury and pneumonia

2005 ◽  
Vol 16 (1) ◽  
pp. 3-10
Author(s):  
Goda Choi ◽  
Esther K. Wolthuis ◽  
Marcel Levi ◽  
Tom Van Der Poll ◽  
Marcus J. Schultz
Critical Care ◽  
2008 ◽  
Vol 12 (2) ◽  
pp. R41 ◽  
Author(s):  
Dana McClintock ◽  
Hanjing Zhuo ◽  
Nancy Wickersham ◽  
Michael A Matthay ◽  
Lorraine B Ware

2006 ◽  
Vol 291 (3) ◽  
pp. L307-L311 ◽  
Author(s):  
Lorraine B. Ware ◽  
Eric Camerer ◽  
Karen Welty-Wolf ◽  
Marcus J. Schultz ◽  
Michael A. Matthay

Substantial progress has been made in understanding the contribution of alterations in coagulation and fibrinolysis to the pathogenesis of acute lung injury (ALI). Findings from mouse, rat, baboon, and human studies indicate that alterations in coagulation and fibrinolysis may be of major pathogenetic importance in ALI and other inflammatory conditions in the lung including pneumonia, sepsis, and ventilator-induced lung injury. Therapies targeted at both activation of coagulation through the extrinsic coagulation cascade and modulation of coagulation through the protein C system have the potential to favorably impact clinical ALI/acute respiratory distress syndrome.


2005 ◽  
Vol 16 (1) ◽  
pp. 3-10
Author(s):  
Goda Choi ◽  
Esther Wolthuis ◽  
Marcel Levi ◽  
Tom Van Der Poll ◽  
Marcus Schultz

2020 ◽  
Vol 36 (11) ◽  
pp. 929-936
Author(s):  
Lin‐Qiang Tian ◽  
Zhi‐Hao Guo ◽  
Wei‐Zheng Meng ◽  
Long Li ◽  
Yue Zhang ◽  
...  

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