Gestational diabetes: maternal weight gain in relation to fetal growth, treatment modality, BMI and glycemic control

2012 ◽  
Vol 25 (11) ◽  
pp. 2458-2463 ◽  
Author(s):  
Orli Most ◽  
Oded Langer
2008 ◽  
Vol 199 (6) ◽  
pp. S225
Author(s):  
Lisa Simmonds ◽  
Janice Teixeira ◽  
Lois Brustman ◽  
Karen Playforth ◽  
Carolyn Salafia ◽  
...  

2019 ◽  
Vol 8 (4) ◽  
pp. 429 ◽  
Author(s):  
Maria Cristina Aisa ◽  
Benito Cappuccini ◽  
Antonella Barbati ◽  
Graziano Clerici ◽  
Elisabetta Torlone ◽  
...  

Fetal exposure to gestational diabetes mellitus (GDM) seems to stimulate a negative impact on the kidneys. Renal volumes and urinary biomarkers of renal function and tubular impairment and injury were evaluated in 30–40-day old newborns of GDM mothers (n = 139) who needed insulin therapy during pregnancy. We found that neonates of mothers who maintained strict control over normoglycemia (n = 65) during pregnancy and fulfilled the other criteria of the GDM management program showed no differences compared to control (n = 55). Conversely, those (n = 74), whose mothers did not maintain glycemic control and were not compliant to the management program, exhibited significantly lower levels of renal volumes and higher activity of N-acetyl-β-D-glucosaminidase and cathepsin B. Differences due to maternal pre-gestational and gestational body mass index (BMI) as well as to maternal weight gain were demonstrated. Our findings indicate that a multidisciplinary approach, which involves an appropriate management of GDM, prevents the negative effects of GDM on the kidneys at 30–40 days of postnatal age, indicating the fundamental role of glycemic control, as well as of an adequate range of maternal weight gain. Total renal volume, cortical volume, and urinary activity of N-acetyl-β-D-glucosaminidase and cathepsin B may be suggested as indicators for the early recognition of GDM neonates at long-term risk of hypertension and kidney disease.


1997 ◽  
Vol 37 (3) ◽  
pp. 372-373
Author(s):  
MC Nuttens ◽  
O. Verier-Mine ◽  
S. Biausque ◽  
A. Wambergue ◽  
M. Romon

2009 ◽  
Vol 201 (6) ◽  
pp. S113
Author(s):  
Dimitrios Mastrogiannis ◽  
Emily Fischer ◽  
Tasmia Henry ◽  
Wadia Mulla ◽  
Stamatios Mastrogiannis ◽  
...  

2013 ◽  
Vol 0 (0) ◽  
pp. 1-6 ◽  
Author(s):  
Edyta Horosz ◽  
Dorota A. Bomba-Opon ◽  
Monika Szymanska ◽  
Miroslaw Wielgos

2018 ◽  
Vol 62 (1) ◽  
pp. 55-63
Author(s):  
Livia S. Mastella ◽  
Letícia S. Weinert ◽  
Vanessa Gnielka ◽  
Vânia N. Hirakata ◽  
Maria Lúcia R. Oppermann ◽  
...  

2006 ◽  
Vol 92 (3) ◽  
pp. 272-278 ◽  
Author(s):  
H. Takimoto ◽  
T. Sugiyama ◽  
H. Fukuoka ◽  
N. Kato ◽  
N. Yoshiike

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