The association between previous single first trimester abortion and pregnancy outcome in nulliparous women

2015 ◽  
Vol 29 (9) ◽  
pp. 1457-1461 ◽  
Author(s):  
Liran Hiersch ◽  
Eran Ashwal ◽  
Amir Aviram ◽  
Shlomi Rayman ◽  
Arnon Wiznitzer ◽  
...  
2021 ◽  
pp. bmjsrh-2020-200795
Author(s):  
Blair G Darney ◽  
Evelyn Fuentes-Rivera ◽  
Biani Saavedra-Avendano ◽  
Patricio Sanhueza-Smith ◽  
Raffaela Schiavon

IntroductionWe examined parity and age among women seeking an abortion in Mexico City’s public first-trimester abortion programme, Interrupcion Legal de Embarazo (ILE). We hypothesised that younger women, especially students, used abortion to prevent first births while older women used abortion to limit births.MethodsWe used clinical data from a sample of 47 462 women who had an abortion between 2007 and 2016 and classified them as nulliparous or parous according to previous births prior to the abortion. We used logistic regression to identify sociodemographic and clinical factors associated with using abortion to prevent a first birth (nulliparous) versus limiting births (parous) and calculated absolute multivariable predicted probabilities.ResultsOverall, 41% of abortions were in nulliparous women seeking to prevent a first birth, and 59% were in women who already had one or more children. The adjusted probability of using abortion to prevent a first birth was 80.4% (95% CI 78.3 to 82.4) for women aged 12–17 years and 54.3% (95% CI 51.6 to 57.0) for women aged 18–24 years. Adolescents (aged 12–17 years) who were employed or students had nearly 90% adjusted probability of using abortion to prevent a first birth (employed 87.8%, 95% CI 82.9 to 92.8; students 88.5%, 95% CI 82.9 to 94.1). At all ages, employed women and students had higher probabilities of using abortion to prevent a first birth compared with unemployed women and women who work in the home.ConclusionLegal first-trimester abortion services in Mexico can help prevent first births in adolescents, especially students.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Luciana Pietro ◽  
Fátima Bottcher-Luiz ◽  
Lício Augusto Velloso ◽  
Joseane Morari ◽  
Marcelo Nomura ◽  
...  

Abstract Blastocyst implantation and neoplastic invasion have some common properties related to tissue invasion, mediated by various cytokines. Aim To compare the expression of IL-6, STAT-3 and telomerase in material of abortions in the first trimester of pregnancy, at term placentas and in choriocarcinomas. Methods Immunohistochemical reactions were performed on formalin fixed and included in paraffin samples from 3 groups: abortions, normal at term placentas and choriocarcinomas. Western Blot and Real-Time PCR assays were performed on fresh material from BeWo cell line and in primary culture cells of normal placenta. Results Immunohistochemical reactions: IL-6 expression was moderate in the first trimester abortion samples and high in at term placentas and choriocarcinomas. STAT-3 was strongly positive in all groups. Telomerase expression was absent in normal at term placentas but was increased in BeWo cells. Conclusion IL-6 and STAT-3 are present in the invasion process of the normal placental development and they are maintained during the malignant transformation to choriocarcinoma. The intense telomerase expression observed in BeWo cells was strongly associated with the malignant phenotype, confirming it as a good marker for cell transformation and tumor progression.


2012 ◽  
Vol 27 (9) ◽  
pp. 2671-2675 ◽  
Author(s):  
T. Ghi ◽  
F. De Musso ◽  
E. Maroni ◽  
A. Youssef ◽  
L. Savelli ◽  
...  

2002 ◽  
Vol 22 (9) ◽  
pp. 778-782 ◽  
Author(s):  
Yuval Yaron ◽  
Sigal Heifetz ◽  
Yifat Ochshorn ◽  
Ofer Lehavi ◽  
Avi Orr-Urtreger

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