SAFETY OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, INCLUDING ASPIRIN, AND PARACETAMOL (ACETAMINOPHEN) IN PEOPLE RECEIVING METHOTREXATE FOR INFLAMMATORY ARTHRITIS (RHEUMATOID ARTHRITIS, ANKYLOSING SPONDYLITIS, PSORIATIC ARTHRITIS, OTHER SPONDYLOARTHRITIS)

2012 ◽  
Vol 26 (2) ◽  
pp. 171-171
2019 ◽  
Vol 20 (7) ◽  
pp. 1646 ◽  
Author(s):  
Chih-Hsin Tang

Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis and inflammatory arthritis. The exact etiology of arthritis remains unclear and no cure exists. Anti-inflammatory drugs are commonly used in the treatment of arthritis, but are associated with significant side effects. Novel modes of therapy and additional prognostic biomarkers are urgently needed for these patients. In this editorial, the twenty articles published in the Special Issue Research of Pathogenesis and Novel Therapeutics in Arthritis 2019 are summarized and discussed as part of the global picture of the current understanding of arthritis.


2009 ◽  
Vol 2 (10) ◽  
pp. 585-596
Author(s):  
John Stevenson

Inflammatory arthritis is an umbrella term used to describe a range of conditions, including rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and reactive arthritis. These are autoimmune diseases in which joint and systemic features are present in varying degrees between disease processes and individuals. Delayed diagnosis can lead to irreversible joint destruction and dysfunction but a therapeutic revolution has transformed its prognosis. Ever-expanding therapeutic options require GPs to recognize these conditions, manage symptoms and undertake drug monitoring. The costs to individuals, their families and the National Health Service are high. There were 1.9 million GP consultations for inflammatory arthritis in 2000 and nearly 46000 hospital admissions. The challenge in primary care is to recognize an inflammatory arthritis early and refer to secondary care.


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