Idiopathic sudden sensorineural hearing loss in elderly patients: Univariate and multivariate analysis of potential clinical prognostic factors

2014 ◽  
Vol 12 (4) ◽  
pp. 182-188
Author(s):  
Marco Lionello ◽  
Giulia Tealdo ◽  
Stefano Breda ◽  
Luciano Giacomelli ◽  
Alberto Staffieri ◽  
...  
2015 ◽  
Vol 125 (9) ◽  
pp. 2209-2215 ◽  
Author(s):  
Jae Ho Chung ◽  
Seok Hyun Cho ◽  
Jin Hyeok Jeong ◽  
Chul Won Park ◽  
Seung Hwan Lee

2004 ◽  
Vol 131 (2) ◽  
pp. P49-P49
Author(s):  
John Xenellis ◽  
Ioannis G Karapatsas ◽  
Nikolaos Papadimitriou ◽  
Thomas Nikolopoulos ◽  
Paulos Maragoudakis ◽  
...  

2021 ◽  
Vol 8 (12) ◽  
pp. 5830-5835
Author(s):  
Md. Feroz Hossen ◽  
Mahbubul Alam Choudhury

Introduction: Idiopathic sudden sensorineural hearing loss (ISSNHL) is an emergency disease requiring immediate diagnosis and treatment. The incidence of ISSNHL in the Western countries’ population was estimated to 5–20 per 100,000 inhabitants. The etiology of ISSNHL remains unknown. Its pathogenesis is most often suggested to be due to a disturbed microcirculation and infection. Objective: To study the clinical profile & prognostic factors in patients with sudden sensorineural hearing loss. Material and Methods: A retrospective study was carried out from patients of sudden sensineural hearing loss (SSNHL) presenting to ENT Department ofNorthern Private Medical College, Rangpur, Bangladesh from January to June-2020. All patients were given intravenous steroids as treatment modality for 14 days and pure tone audiogram was done every 3 days during hospital admission. It was followed by oral steroids in tapering dose for further 14 days. After 1 month, audiogram was done again. After 1 month if hearing threshold was decreased by more than 50% of presenting one, then it was labeled as improved. Results:Total 51 patients (55ears) with age ranging from 6-70 years (average-38.5 years) were included. Three fourth were male. Presentation was 1-14days after onset of hearing loss (average- 3.7days) with pure tone audiogram (PTA) of 38-117dB (average 83.1dB). The flat audiogram (62.3%) was most common type. Smoking was present in 14 patients and tinnitus in 30 ears. Hemoglobin ranged from 7.3-18.7gm %( average- 15.3gm/dl). PTA post treatment was 8-73dB (average- 56dB). Average age of improved patient was 39.8years which was lower than non-improved patients (42.3years). In improved patients, average PTA at presentation was 77.9dB while it was 86.6dB in non-improved patients. Conclusion: Our study demonstrates that the age distribution and clinical characteristics of ISSNHL patients vary according to levels of hearing loss. Moreover, ISSNHL patients with vertigo tend to sufer from a more severe hearing loss. Further studies are needed to obtain better knowledge about the etiopathogenesis of SSNHL.  SSNHL is more commonly seen in male patients with polycythaemia and is commonly presented in winter season and is frequently associated with tinnitus. Young age and lower audiogram threshold at presentation favor prognosis.


2016 ◽  
Vol 33 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Gamze Atay ◽  
Bahar Kayahan ◽  
Betul Cicek Cinar ◽  
Sarp Sarac ◽  
Levent Sennaroglu

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Pasqua Irene Sciancalepore ◽  
Valentina De Robertis ◽  
Rodolfo Sardone ◽  
Nicola Quaranta

The standard treatment of Sudden Sensorineural Hearing Loss is based on oral steroids. In addition, intratympanic steroid is currently used in patients who fail to respond to oral treatment. The aim of the present study was to evaluate, in patients affected by SSHL, factors that influence the response to systemic and intratympanic steroid treatment. A retrospective analysis was conducted on 149 patients, all treated with systemic steroids. Moreover, patients not responsive to systemic therapy were treated with intratympanic steroids as salvage therapy. Auditory gain was assessed through the recovery rate at the discharge and after 30 days. Statistical analysis demonstrated that patients with delayed treatment and down-sloping auditory curve presented a poor recovery. Linear and stepwise regression showed that hypertriglyceridemia and hyperglycemia were negative prognostic factors. The prognosis of SSHL is affected by hyperglycemia and hypertriglyceridemia suggesting that a microvascular dysfunction within the cochlea could impair hearing recovery. Intratympanic steroid treatment was used as salvage treatment, however in patients with poor prognostic factors or at risk for side effects, it could be used in association with systemic treatment.


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