Carboxypeptidase Z is differentially expressed in high-grade serous ovarian cancers.
Keyword(s):
We sought to identify genes associated with high-grade serous ovarian cancer (HGSC) by comparing global gene expression profiles of normal ovary with that of primary tumors from women diagnosed with HGSC using published microarray data (1, 2). We identified carboxypeptidase Z (CPZ) (3) as among the genes whose expression was most different in HGSC ovarian tumors. CPZ expression was significantly lower in ovarian tumors relative to normal ovary. CPZ may be relevant to the biology of high-grade serous ovarian cancers.
2020 ◽
2020 ◽
2020 ◽
2020 ◽
2020 ◽
2020 ◽
2020 ◽
2020 ◽
2020 ◽
2020 ◽