A review Commentary on Quinidine kinetics (PK modelling)
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This article takes you through the possible pharmacokinetic models and parameters for the antiarrhythmic drug Quinidine. The shuffle between the linear and non-linear pharmacokinetics of quinidine make it a candidate for therapeutic drug monitoring. The adverse effect in the form of QT-elongation is one of the major challenges to go for estimating good kinetics of the quinidine. The current article helps in providing a wide perspective towards the available models for the quinidine's ADME and compile the information published by several authors to help you to understand the quinidine pharmacokinetic behaviour.
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2018 ◽
Vol 6
(4)
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pp. e00420
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