scholarly journals Giant Cell Tumor Arising from Fibular Head in Immature Skeleton Treated with Marginal Excision

2018 ◽  
Vol 14 (3) ◽  
pp. 165-167
Author(s):  
Suresh Pandey
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Lateral Collateral Ligament ◽  
Cell Tumor ◽  
Proximal Fibula ◽  
Marginal Excision ◽  
Fourth Decade ◽  
Rare Site ◽  
Bony Lesion ◽  
Immature Skeleton

ABSTRACTGiant Cell tumor (GCT) is the benign tumor commonly found in second to fourth decade of life. Proximal fibula is very rare site and its occurrence in immature skeleton is still rare with very limited case report. We present a case of painful bony lesion arising from proximal fibula diagnosed as GCT in 15 year boy which was managed successfully with marginal excision and lateral collateral ligament anchorage in proximal tibia. There is no evidence of local recurrence,  lung metastasis, knee pain and instability till 24 months of follow up. Keywords: giant cell tumor; proximal fibula; marginal excision . 

scholarly journals A Case Report of Giant Cell Tumor of Proximal Fibula in Children

2020 ◽  
Vol 4 (1) ◽  
pp. 64-67
Author(s):  
Sushil Adhikari ◽  
Arun Sigdel ◽  
Rajesh Kumar Sah ◽  
Luna Devkota
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Long Bone ◽  
Lytic Lesion ◽  
Radiographic Appearance ◽  
X Ray ◽  
Proximal Fibula ◽  
Aggressive Tumor

Giant cell tumour (GCT) is histopathologically benign tumor of long bone particularly in distal femur and the proximal tibia. It commonly occurs in adults of age 20-40 years but rare in children. GCT is considered to be locally aggressive tumor and tendency of recurrence is higher even after surgery. The clinical features are nonspecific, the principle symptoms are pain, swelling and limiting adjacent joint movements. Diagnosis is based on the radiographic appearance and histopathological findings .In our case X-ray showed ill defined lytic lesion on proximal fibula with cortical thinning and MRI finding revealed expansile lyticlesion in meta-epiphysis of right fibula 16×16×28mm adjacent to growth plate with fluid level. The sclerotic rim appears hypo intense on T1 & hyper intense on T2. Core needle biopsy showed giant cell tumor on proximal fibula. Considering the risk of recurrence wide local excision was done. Management of GCT of proximal fibula in young patient is critical for preventing recurrence and enhancing functional outcomes by saving adjacent anatomical structure. No evidence of local recurrence and metastasis was found in 24 months of follow up.

Sphenoid bone: a rare site for giant cell tumor – case report with literature review

2016 ◽  
Vol 35 (11) ◽  
pp. 385-388 ◽  
Author(s):  
Debajyoti Chatterjee ◽  
Kirti Gupta ◽  
Navneet Singla ◽  
Ankur Kapoor
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Sphenoid Bone ◽  
Rare Site

scholarly journals Giant Cell Tumor: A Rare Condition in the Immature Skeleton—A Retrospective Study of Symptoms, Treatment, and Outcome in 16 Children

Sarcoma ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Thale M. Asp Strøm ◽  
Anette Torød Skeie ◽  
Ingvild Koren Lobmaier ◽  
Olga Zaikova
Keyword(s):  
Retrospective Study ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Rare Condition ◽  
Functional Results ◽  
Cell Tumor ◽  
Initial Symptom ◽  
Recurrence Rates ◽  
Intralesional Curettage ◽  
Immature Skeleton

Background. Pediatric giant cell tumor (GCT) of bone is rare and the course of the disease in the immature skeleton is sparsely described. We performed a retrospective study addressing symptoms, treatment, and outcome in children with GCT.Methods. Review of medical records and images of patients with GCT. Patients were detected from our hospital prospective database and those with open epiphyseal cartilages were included.Results. 16 children (75% girls) from 6 to 15 years old were identified. Eight lesions (50%) were in long bones and 4 (25%) in flat bones. One lesion appeared to be purely epiphyseal. All patients had pain as the initial symptom. Local recurrence developed in 2 patients. 14 of 16 patients returned to normal activity with no sequelae. One patient developed anisomelia after surgery.Conclusions. The biological tumor behavior in children does not seem to differ from what is reported in adults. Lesions in flat bones are very unusual, but our data alone do not provide enough evidence to conclude that this is more common in the immature skeleton. Literature review showed only one previous case report describing a purely epiphyseal GCT. Intralesional curettage is appropriate treatment and gives good functional results with acceptable recurrence rates.

Giant cell tumor of talus, a case report of rare site

2007 ◽  
Vol 61 (2) ◽  
pp. 73-75 ◽  
Author(s):  
Munirpasha N. Sayed ◽  
Sharad Kondekar ◽  
Suruchi Jaiswal ◽  
Darshana Rasalkar ◽  
Sachin Agrawal
Keyword(s):  
Case Report ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Rare Site

Giant cell tumor of the proximal fibula: Surgical management

1996 ◽  
Vol 61 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Hosein Faezypour ◽  
Aileen M. Davis ◽  
Anthony M. Griffin ◽  
Robert S. Bell
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Surgical Management ◽  
Cell Tumor ◽  
Proximal Fibula

scholarly journals A posterior approach for curettage in giant cell tumor of bone in the proximal fibula

2019 ◽  
Vol 2019 (9) ◽  
Author(s):  
Akio Sakamoto ◽  
Takeshi Okamoto ◽  
Shuichi Matsuda
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Peroneal Nerve ◽  
Posterior Approach ◽  
En Bloc Resection ◽  
Cell Tumor ◽  
Knee Instability ◽  
En Bloc ◽  
Nerve Paralysis ◽  
Proximal Fibula

Abstract Giant cell tumor of bone (GCTB) is a locally aggressive tumor. En bloc resection to reduce the recurrence rate has a high risk of peroneal nerve paralysis and knee instability associated with collateral ligament resection. In the current report, the posterior approach to curettage is introduced in a 55-year-old male with GCTB in the proximal fibula. The approach makes a wide operative field for curettage of GCTB in the proximal fibula without dissecting the peroneal nerve. The approach would prevent postoperative peroneal nerve palsy and knee instability and possibly reduce recurrences.

scholarly journals A Pregnant Woman with Multi-Fragmented Giant Cell Tumor of Tendon Sheath: A Rare Anatomical Location

2020 ◽  
Vol 110 (3) ◽  
Author(s):  
Mehmet Arican ◽  
Yalçın Turhan
Keyword(s):  
Differential Diagnosis ◽  
Pregnant Woman ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Tendon Sheath ◽  
Cell Tumor ◽  
Flexor Hallucis Longus ◽  
Marginal Excision ◽  
Definitive Method ◽  
Web Space

Giant cell tumor of the tendon sheath (GCTTS) in the foot is a rare pathology and is involved in the differential diagnosis of soft-tissue tumors of the foot and ankle. Although it can affect any age group, GCTTS mainly occurs at the 3rd and 5th decade and is more common in females. Histopathologic examination is a major definitive method for diagnosis, although physical examination and radiologic imaging are helpful in reaching a diagnosis preoperatively. Many treatment options exist but marginal excision is the most commonly used treatment. We describe the case of a 26-year-old pregnant woman with a multi-fragmented mass extending from the first web space to the plantar aspect of the metatarsophalangeal joint (MTP) of the left great toe associated with flexor hallucis longus tendon after trauma. She had pain that worsened with activity and wearing shoes. After pregnancy, a marginal excision with dorsal longitudinal incision in the first web space was performed under spinal anesthesia. The lesion was diagnosed as a localized type tenosynovial giant cell tumor. At the last follow-up appointment in the 23rd month, the patient was doing well and there was no recurrence of the lesion. GCSST should be considered in the differential diagnosis of plantar masses of foot. Although, GCTTS is frequently seen in females, it has not been previously reported in a pregnant woman with an extremely rare condition after trauma.

scholarly journals Neoadjuvant and Adjuvant Treatment with Denosumab in Aggressive Giant-cell Tumor of Bone in the Proximal Fibula: a Case Report

Folia Medica ◽  
2018 ◽  
Vol 60 (4) ◽  
pp. 637-640 ◽  
Author(s):  
Violeta V. Marinova ◽  
Svetoslav A. Slavchev ◽  
Kircho D. Patrikov ◽  
Petya M. Tsenova ◽  
Georgi P. Georgiev
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Target Therapy ◽  
Osteolytic Lesion ◽  
Therapy Response ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Treatment Modalities ◽  
Histological Changes ◽  
Proximal Fibula

Abstract Giant cell tumor of bone is a histologically benign but locally aggressive osteolytic lesion, capable of spreading ‘benign’ metastases mainly to the lungs. Since its description as a separate entity, surgery has been the mainstay of treatment. Recently, target therapy has been introduced using denosumab – an inhibitor antibody for the receptor activator of nuclear factor kappa B ligand with dramatic eff ect on the natural course of the tumor. Herein, we report a rare case of an aggressive stage 3 giant cell tumor of bone of the proximal fibula that was successfully downstaged using neoadjuvant denosumab treatment and then treated by surgical excision followed by adjuvant target therapy. The clinical characteristics and treatment modalities of giant cell tumor of bone, the indications for target therapy, therapy response, and histological changes are also briefly discussed.

scholarly journals EVALUATION OF RESULTS OF WIDE RESECTION AND RECONSTRUCTION USING NON - VASCULARISED IPSILATERAL PROXIMAL FIBULA FOR GIANT CELL TUMOR OF LOWER END OF RADIUS

2015 ◽  
Vol 4 (53) ◽  
pp. 9186-9190
Author(s):  
Sujai S ◽  
Jayakrishnan S ◽  
Abhijeet Jayaswal ◽  
Siddalingaswamy M K ◽  
Venugopal N
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Wide Resection ◽  
Proximal Fibula
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