scholarly journals Wilm’s Tumor: Ten Year Experience at Kanti Children’s Hospital

1970 ◽  
Vol 30 (2) ◽  
pp. 85-89 ◽  
Author(s):  
Kailash Prasad Sah ◽  
Ganesh Kumar Rai ◽  
PN Shrestha ◽  
Amit Shrestha

Introduction: Wilm's tumor is the second most common abdominal tumor in children. It arises from thekidney. The survival of children with Wilm's tumor has improved over the past 25 years. Objectives: Tostudy the clinical presentation of Wilm’s tumor and evaluate the ten year survival. Materials and Methods:A retrospective hospital based study was conducted at Kanti Children's Hospital from March 1998 toFebruary 2008. A total of 60 histopathologically diagnosed children below 14 yr of age were included inthe study. Results: About 2/3rd (66.5%) presented with abdominal swelling followed by abdominal pain(16.5%) and fever (13.5%). A few children manifested with red colored urine (3.5%). The age of childrenranged from one month to 13 years with the mean age of 36 months. Males were affected more than thefemales (M:F=3:1). Most affected age group was 2 to 5 yrs (41.5%) followed by 1 to 2 yrs (25.0%). Mostof the cases were in stage III (36.5%) followed by stage II (33.5%). SIOP protocol was used to treat thesechildren and overall 10 year survival rate was 50.0%. One fifth (20%) of the cases died, 16.5% relapsedand 13.5% lost to follow up. Conclusion: Despite severe resource limitations, paediatric oncology unit atKanti Children’s Hospital has been successfully treating Wilm's tumor with the success rate of 50.0%.Key words: Chemotherapy; Outcome; Remission; Wilm’s tumor; SIOP.DOI: 10.3126/jnps.v30i2.3449J. Nepal Paediatr. Soc. May-August, 2010 Vol 30(2) 85-89

2020 ◽  
Vol 41 (S1) ◽  
pp. s18-s19
Author(s):  
Ashley Richter

Background: On December 14, 3 unvaccinated siblings with recent international travel presented to Children’s Hospital Colorado emergency department (CHCO-ED) with fever, rash, conjunctivitis, coryza, and cough. Measles was immediately suspected; respiratory masks were placed on the patients before they entered an airborne isolation room, and public health officials (PH) were promptly notified. Notably, on December 12, 1 ill sibling presented to CHCO-ED with fever only. We conducted an investigation to confirm measles, to determine susceptibility of potentially exposed ED contacts and healthcare workers (HCWs), and to implement infection prevention measures to prevent secondary cases. Methods: Measles was confirmed using polymerase chain reaction testing. Through medical record review and CHCO-ED unit-leader interviews, we identified patients and HCWs in overlapping ED areas with the first sibling, until 2 hours after discharge. Measles susceptibility was assessed through interviews with adults accompanying pediatric patients and HCW immunity record reviews. Potentially exposed persons were classified as immune (≥1 documented measles-mumps-rubella (MMR) vaccination or serologic evidence of immunity), unconfirmed immune (self-reported MMR or childhood vaccination without documentation), or susceptible (no MMR vaccine history or age <12 months). Susceptibility status directed disease control intervention, and contact follow-up was 21 days. Results: On December 14, all 3 siblings (ages 8–11 years) had laboratory-confirmed measles and were hospitalized. CHCO’s rapid isolation of the 3 cases within 5 minutes after presentation to the ED eliminated the need for exposure assessment on the day of hospitalization. However on December 12, the 1 ill sibling potentially exposed 258 ED contacts (90 patients, 168 accompanying adults) and 22 HCWs. The PH department identified 158 immune contacts (61%), 75 unconfirmed immune contacts (29%), and 19 susceptible contacts (8%); 6 contacts (2%) were lost to follow-up. Overall, 15 susceptible contacts received immune globulin (IG) postexposure prophylaxis and 4 contacts were placed on 21-day quarantine. Unconfirmed immune contacts self-monitored for measles symptoms and were contacted weekly by PH for 21 days. Moreover, 20 immune HCWs monitored symptoms daily; 2 susceptible HCWs were placed on 21-day quarantine. No secondary cases were identified. Conclusions: Rapid measles identification and isolation, high levels (90%) of immunity among contacts, prompt administration of IG, and effective collaboration between PH and CHCO prevented transmission.Funding: NoneDisclosures: None


1985 ◽  
Vol 93 (5) ◽  
pp. 585-591 ◽  
Author(s):  
Francis I. Catlin ◽  
Elizabeth M. Spankus

We treated 21 children for subglottic stenosis at the Texas Children's Hospital from 1975 to 1983. Ages ranged from newborn to 14 years. Fifteen (71%) were younger than 13 months of age. Prolonged intubation was thought to be a primary contributing factor in 16 of 21 (76%). Nineteen (90%) required tracheotomy. Of these, 11 (58%) were decannulated, four (21%) have not been decannulated, and four (21%) were lost to follow-up. Two of the 11 children who were successfully decannulated required laryngotracheoplasty or thyrotomy. There were three instances of complications and no deaths.


Author(s):  
Thi Ngoc Tran ◽  
Thien Hai Do ◽  
Thi Duyen Tran ◽  
Le Chinh Nguyen

Purpose: To characterize the prevalence and factors associated with ARV adherence in HIV/AIDS-infected children at outpatient clinics, Vietnam National Children's Hospital. Methods: A cross-sectional study was conducted at outpatient clinics, Vietnam National Children's Hospital in 2019. Results: The study results showed that 63% of  HIV/AIDS infected children adhered to treatment and 37% of them did not adhere to ARV. The study investigated the relevance of 11 factors and found 5 factors related to pediatric noncompliance, including a short treatment period of less than 1 year (OR: 17.1; 95% CI: 2,26-75,5 and p < 0,01); waiting time for taking drugs is too long (OR: 19.3; 95% CI: 7.9-50.9 and p < 0.01); main caregivers aged ≥ 50 (OR = 42.3; 95% CI from 17.9-120.1 and p < 0.01. Conclusions: The prevalence of ARV adherence in HIV/AIDS-infected children was 63%. Counseling intervention models to improve drug treatment compliance should be concentrated on newly infected children, treatment duration less than 1 year and their primary caregivers over 50 years old.


2021 ◽  
Vol 04 (03) ◽  
pp. 95-106
Author(s):  
Dinh Pham ◽  
◽  
Quynh Nguyen

Objective: Determine full cost of tonsillectomy at Children’s Hospital 1 in 2019. Methods: Coss–sectional descriptive study 304 tonsillectomy children at Children’s Hospital 1 in 2019. Results: The study results showed that the cost of tonsillectomy (excluding consultation fees and pre-operation tests) depend on surgery devices. The average cost of cautery tonsillectomy was 1,740, 869 VND (68% direct cost, 32% indirect cost), of the coblator tonsillectomy was 3,610,031 VND 84.58% direct cost, 15.46% indirect cost), and of the plasma peak tonsillectomy one was 3,600,124 VND (84.54% direct cost, 15.46% indirect cost). In 3 surgery methods, the percentage’s cost of drugs, medical disposible items, and operation team were the largest share in direct costs; in indirect costs, the percentage of human management was the highest proportion, followed by the percentage of facility maintenance cost, and the percentage of other regular expenses cost was very low. Conclusion: The average cost of cautery tonsillectomy was 1,740, 869 VND, of the coblator tonsillectomy was 3,610,031 VND, and of the plasma peak tonsillectomy one was 3,600,124 VND.This cost is higher than the current hospital fee the patient or the health insurance paid. This implies a mismatch between input costs and hospital rates. Key words: Tonsillectomy cost, Children’s Hospital 1, cautery, Coblator, Plasma Peak Blade.


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