scholarly journals Three-Dimensional Biomodels: Use of Different Materials for the Surgical Planning in Relation to Two Mandibular Cysts Cases

Author(s):  
Astigueta José Mariano ◽  
Astigueta José Mariano ◽  
Mendoza Cuello Norbin José ◽  
Benitez Javier Alejandro ◽  
Attaguile Alberto ◽  
...  

Introduction: The use of three-dimensional models in the diagnosis, planification and treatment of the maxillofacial area pathology has been included in publications since 1980, and has enabled to minimize surgical time, reducing peri and postoperative morbidity, and optimizing surgical results. Currently, the market offers a huge range of 3D printers and materials which allows biomodels to be printed for medical purposes. The purpose of the following paper is to describe the use of two types of three-dimensional models in the therapeutic planning of two cases of mandibular cysts. Case Report: Two cases of mandibular dentigerous cysts are described, in which osteosynthesis plates were used to prevent pathological fractures, pre-modeled together with acrylic positioners on three-dimensional models and printed in different ways. Postoperative clinical and tomographic controls were performed. Conclusion: The knowledge of the properties of the different materials available for the construction of three-dimensional models allows selecting the one that best suits the case needs required, minimizing surgical times and optimizing the results.

Author(s):  
André Rafael Liziero ◽  
Maria Ivete Basniak

Three-dimensional representations have been used in teaching for several decades. However, these representations were made primarily using materials available in the market. The use of 3D printers has extended the possibility of creating and printing these objects, enabling the printing of three-dimensional models using computer designs. These computational designs or 3D computational modeling are built employing various software programs, which require reflections and strategies during their production. In this chapter, the authors discuss the possibilities of using the OpenSCAD software 3D models for teaching mathematics.


Surgery ◽  
2020 ◽  
Vol 167 (2) ◽  
pp. 259-263 ◽  
Author(s):  
Michael G. Bateman ◽  
William K. Durfee ◽  
Tinen L. Iles ◽  
Cindy M. Martin ◽  
Kenneth Liao ◽  
...  

2003 ◽  
Vol 125 (3) ◽  
pp. 520-532 ◽  
Author(s):  
P. Emery ◽  
F. Maroteaux ◽  
M. Sorine

Gasoline direct injection (GDI) spark ignition engines may be able to run over a wide range of operating conditions. The GDI process allows combustion with lean mixtures which may lead to improved fuel economy and emissions relative to homogeneous spark ignition (SI) engines. To satisfy the different modes of operation, the tuning of GDI engines requires a large number of engine tests which are time-consuming and very expensive. To reduce the number of tests, a model with a very short computational time to simulate the engines in the whole operating range is needed; therefore the objective of this paper is to present a reduced model to analyze the combustion process in GDI engines, applied to a homogeneous stoichiometric mode. The objective of the model is to reproduce the same tendencies as those obtained by three-dimensional models, but with a reduced computational time. The one-dimensional model is obtained thanks to a reduction methodology based on the geometry of the combustion front computed with three-dimensional models of the KIVA-GSM code, a modified version of KIVA-II code including a CFM combustion model. The model is a set of n one-dimensional equations (i.e., for n rays), taking into account a thin flame front, described with the flamelet assumption. It includes a CFM combustion model and a (k,ε)-model including the mean air motions (swirl and tumble). The results of the one-dimensional model are compared to those obtained by the KIVA IIGSM under different engine conditions. The comparison shows that the one-dimensional model overestimates the maximum cylinder pressure, which has an insignificant effect on the net indicated work per cycle. The results obtained by the numerical simulations are close to those given by the three-dimensional model, with a much reduced computation time.


1989 ◽  
Vol 111 (3) ◽  
pp. 204-210 ◽  
Author(s):  
Y. H. Zurigat ◽  
K. J. Maloney ◽  
A. J. Ghajar

A survey of the stratified thermal storage tank one-dimensional models available in the literature has been conducted. Six of these models were tested and compared against the experimental data obtained at our laboratories and from the literature. Although various factors affecting the performance of a stratified tank can be accounted for by the higher order models, i.e. two- and three-dimensional models, the introduction of empirically-based mixing parameters into the one-dimensional models renders them widely applicable and practical in the simulation of energy systems incorporating thermal storage tanks.


1975 ◽  
Vol 39 (8) ◽  
pp. 544-546
Author(s):  
HL Wakkerman ◽  
GS The ◽  
AJ Spanauf

2020 ◽  
Vol 17 (4) ◽  
pp. 342-351
Author(s):  
Sergio A. Durán-Pérez ◽  
José G. Rendón-Maldonado ◽  
Lucio de Jesús Hernandez-Diaz ◽  
Annete I. Apodaca-Medina ◽  
Maribel Jiménez-Edeza ◽  
...  

Background: The protozoan Giardia duodenalis, which causes giardiasis, is an intestinal parasite that commonly affects humans, mainly pre-school children. Although there are asymptomatic cases, the main clinical features are chronic and acute diarrhea, nausea, abdominal pain, and malabsorption syndrome. Little is currently known about the virulence of the parasite, but some cases of chronic gastrointestinal alterations post-infection have been reported even when the infection was asymptomatic, suggesting that the cathepsin L proteases of the parasite may be involved in the damage at the level of the gastrointestinal mucosa. Objective: The aim of this study was the in silico identification and characterization of extracellular cathepsin L proteases in the proteome of G. duodenalis. Methods: The NP_001903 sequence of cathepsin L protease from Homo sapienswas searched against the Giardia duodenalisproteome. The subcellular localization of Giardia duodenaliscathepsin L proteases was performed in the DeepLoc-1.0 server. The construction of a phylogenetic tree of the extracellular proteins was carried out using the Molecular Evolutionary Genetics Analysis software (MEGA X). The Robetta server was used for the construction of the three-dimensional models. The search for possible inhibitors of the extracellular cathepsin L proteases of Giardia duodenaliswas performed by entering the three-dimensional structures in the FINDSITEcomb drug discovery tool. Results: Based on the amino acid sequence of cathepsin L from Homo sapiens, 8 protein sequences were identified that have in their modular structure the Pept_C1A domain characteristic of cathepsins and two of these proteins (XP_001704423 and XP_001704424) are located extracellularly. Threedimensional models were designed for both extracellular proteins and several inhibitory ligands with a score greater than 0.9 were identified. In vitrostudies are required to corroborate if these two extracellular proteins play a role in the virulence of Giardia duodenalisand to discover ligands that may be useful as therapeutic targets that interfere in the mechanism of pathogenesis generated by the parasite. Conclusion: In silicoanalysis identified two proteins in the Giardia duodenalisprotein repertoire whose characteristics allowed them to be classified as cathepsin L proteases, which may be secreted into the extracellular medium to act as virulence factors. Three-dimensional models of both proteins allowed the identification of inhibitory ligands with a high score. The results suggest that administration of those compounds might be used to block the endopeptidase activity of the extracellular cathepsin L proteases, interfering with the mechanisms of pathogenesis of the protozoan parasite Giardia duodenalis.


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