Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects ≥1 Month to <17 Years Undergoing MRI Scans

Author(s):  
2019 ◽  
Vol 130 (6) ◽  
pp. 1428-1430
Author(s):  
Neelam Phalke ◽  
W. Walsh Thomas ◽  
James Azzi ◽  
Ryan J. Li ◽  
Daniel Petrisor ◽  
...  

2020 ◽  
Vol 102-B (4) ◽  
pp. 501-505 ◽  
Author(s):  
Ramal Gnanasekaran ◽  
Nicholas Beresford-Cleary ◽  
Tariq Aboelmagd ◽  
Karim Aboelmagd ◽  
Daniel Rolton ◽  
...  

Aims Early cases of cauda equina syndrome (CES) often present with nonspecific symptoms and signs, and it is recommended that patients undergo emergency MRI regardless of the time since presentation. This creates substantial pressure on resources, with many scans performed to rule out cauda equina rather than confirm it. We propose that compression of the cauda equina should be apparent with a limited sequence (LS) scan that takes significantly less time to perform. Methods In all, 188 patients with suspected CES underwent a LS lumbosacral MRI between the beginning of September 2017 and the end of July 2018. These images were read by a consultant musculoskeletal radiologist. All images took place on a 3T or 1.5T MRI scanner at Stoke Mandeville Hospital, Aylesbury, UK, and Royal Berkshire Hospital, Reading, UK. Results The 188 patients, all under the age of 55 years, underwent 196 LS lumbosacral MRI scans for suspected CES. Of these patients, 14 had cauda equina compression and underwent emergency decompression. No cases of CES were missed. Patients spent a mean 9.9 minutes (8 to 10) in the MRI scanner. Conclusion Our results suggest that a LS lumbosacral MRI could be used to diagnose CES safely in patients under the age of 55 years, but that further research is needed to assess safety and efficacy of this technique before changes to existing protocols can be recommended. In addition, work is needed to assess if LS MRIs can be used throughout the spine and if alternative pathology is being considered. Cite this article: Bone Joint J 2020;102-B(4):501–505.


Author(s):  
M.J. Hennessy ◽  
E. Kwok

Much progress in nuclear magnetic resonance microscope has been made in the last few years as a result of improved instrumentation and techniques being made available through basic research in magnetic resonance imaging (MRI) technologies for medicine. Nuclear magnetic resonance (NMR) was first observed in the hydrogen nucleus in water by Bloch, Purcell and Pound over 40 years ago. Today, in medicine, virtually all commercial MRI scans are made of water bound in tissue. This is also true for NMR microscopy, which has focussed mainly on biological applications. The reason water is the favored molecule for NMR is because water is,the most abundant molecule in biology. It is also the most NMR sensitive having the largest nuclear magnetic moment and having reasonable room temperature relaxation times (from 10 ms to 3 sec). The contrast seen in magnetic resonance images is due mostly to distribution of water relaxation times in sample which are extremely sensitive to the local environment.


2005 ◽  
Vol 173 (4S) ◽  
pp. 218-218
Author(s):  
William DeFoor ◽  
Denise Ferguson ◽  
Susan Mashni ◽  
Deborah Reeves ◽  
Lisa Creelman ◽  
...  
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2015 ◽  
Vol 21 ◽  
pp. 291-292
Author(s):  
Shashank Joshi ◽  
Jothydev Kesavadev ◽  
Sudhir Bhandari ◽  
Banshi Saboo ◽  
Ashok Jaiswal ◽  
...  

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