scholarly journals Controllable Fabrication and Characterization of Gold Nanoparticles: Enhanced Therapeutic Approaches in Cancer

2019 ◽  
Vol 2 (1) ◽  
pp. 26-28
Author(s):  
Aqsa Ikram ◽  
Yasir Jamil ◽  
Tahira Ahmad ◽  
Hira Ikram ◽  
Amna Ameen ◽  
...  
Keyword(s):  
Well Being ◽  
Nano Particles ◽  
Cell Labeling ◽  
Therapeutic Approaches ◽  
Laser Hyperthermia ◽  
Seed Growth ◽  
Gold Nano Particles ◽  
Controllable Fabrication ◽  
Cancerous Cells

Energy trans-ducting gold nano-particles, with well-being physical, chemical and optical properties for utilization in different types of cancer therapy can be prepared through chemical seed growth reduction method. Gold nano particle is a umbrella term have a variety of size and shape. More regular gold nano-particles can be obtained by reduction of HAuCl4, selection of chemicals and parameters of growth medium are set in accordance with the required category of nano-particles. Nano-particles have longest dimension of 100 nm. Therapeutic treatments like photo-imaging, gene delivery, drug delivery, cell labeling and photo thermal therapy   can be done by gold nano particles.  They reduce the side effects of conventional therapy due to high target specificity and absorb and scatter specific wavelength of laser. Hyperthermia in cancerous cells is generated without damaging surrounding healthy tissues, cause the cell death by necrosis and apoptosis. The overall morphology of gold nano particles can be characterized by SEM and TEM.

scholarly journals Photopyroelectric Techniques for thermo-optical characterization of gold nano-particles

2015 ◽  
Vol 582 ◽  
pp. 012027 ◽  
Author(s):  
B E Chávez-Sandoval ◽  
J A Balderas-López ◽  
G Padilla-Bernal ◽  
M A Moreno-Rivera ◽  
M O Franco-Hernández ◽  
...  
Keyword(s):  
Optical Characterization ◽  
Nano Particles ◽  
Gold Nano Particles

scholarly journals Characterization of multiphoton emission from aggregated gold nano particles

2016 ◽  
Author(s):  
Akira Eguchi ◽  
Phat Lu ◽  
Youngsik Kim ◽  
Tom D. Milster
Keyword(s):  
Nano Particles ◽  
Gold Nano Particles

Preparation and Characterization of Gold Nano-Particles Chemisorbed by π-Radical Thiols

2002 ◽  
Vol 31 (10) ◽  
pp. 1030-1031 ◽  
Author(s):  
Genta Harada ◽  
Hiromi Sakurai ◽  
Michio M. Matsushita ◽  
Akira Izuoka ◽  
Tadashi Sugawara
Keyword(s):  
Nano Particles ◽  
Gold Nano Particles

scholarly journals Monte Carlo study on the gold and gadolinium nanoparticles radio-sensitizer effect in the prostate 125I seeds radiotherapy

2019 ◽  
Vol 25 (3) ◽  
pp. 165-169
Author(s):  
Amir Ghasemi-Jangjoo ◽  
Hosein Ghiasi
Keyword(s):  
Monte Carlo ◽  
Average Energy ◽  
Low Energy ◽  
Nano Particles ◽  
High Dose ◽  
Prostate Brachytherapy ◽  
Gold Nano Particles ◽  
Computational Phantom ◽  
Ct Slices

Abstract Monte Carlo and TL dosimetry applied to the characterization of 125I brachytherapy with a different design with other 125I seeds. In a water phantom, lattice configuration simulated with 125I seed in the center and 10 nm gold and gadolinium nan-particle filed voxels. This simulation conducted to the characterization of the nano-particles DEF in low energy and prostate tissue. To study of the prostate brachytherapy, a humanoid computational phantom developed by CT slices applied. KTMAN-2 computational phantom contains 29 organs and 19 skeletal regions and was produced from cross-sectional x-ray computed tomography (CT slices) images. The simulated seed was 125I seed having an average energy of 28.4 keV for photons, a half-life of 59.4 days. DEF factor in the seed radiation energy (28.4 keV) DEF factor was found to be two times higher for the gold nano-particles. It was revealed than gold-nano-particles posing Z about 1.24 times higher than gadolinium led to around 200% DEF increasing in the same conditions and the nano-particles size. It was concluded that in low energy sources brachytherapy, photoelectric is dominant in the presence of relative high element nanoparticles. This leads to a high dose increasing in some micro-meters and causes a dramatic dose gradient in the vicinity of a nano-particle. This dose gradient effectively kills the tumor cells in continuous low energy irradiation in the presence of a high Z material nano-scaled particle. Application of gold nano-particles in low energy brachytherapy is recommended.

Coherent electron nanodiffraction from clean silver nano particles in a UHV STEM

1993 ◽  
Vol 51 ◽  
pp. 1058-1059
Author(s):  
J. Liu ◽  
M. Pan ◽  
G. E. Spinnler
Keyword(s):  
Supported Catalysts ◽  
Imaging Techniques ◽  
Nano Particles ◽  
Metal Particles ◽  
Shape Structure ◽  
Dynamical Simulations ◽  
Small Metal Particles ◽  
Extract Information

Small metal particles have peculiar chemical and physical properties as compared to bulk materials. They are especially important in catalysis since metal particles are common constituents of supported catalysts. The structural characterization of small particles is of primary importance for the understanding of structure-catalytic activity relationships. The shape and size of metal particles larger than approximately 5 nm in diameter can be determined by several imaging techniques. It is difficult, however, to deduce the shape of smaller metal particles. Coherent electron nanodiffraction (CEND) patterns from nano particles contain information about the particle size, shape, structure and defects etc. As part of an on-going program of STEM characterization of supported catalysts we report some preliminary results of CEND study of Ag nano particles, deposited in situ in a UHV STEM instrument, and compare the experimental results with full dynamical simulations in order to extract information about the shape of Ag nano particles.

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