scholarly journals An unusual presentation of pediatric osteoblastoma in a patient with Klippel-Trenaunay-Weber syndrome: case report

2015 ◽  
Vol 15 (6) ◽  
pp. 638-640 ◽  
Author(s):  
Scott A. Wallace ◽  
Romeo C. Ignacio ◽  
Arnett Klugh ◽  
Gregory Gates ◽  
Marion C. W. Henry
Keyword(s):  
Case Report ◽  
Bone Tumor ◽  
Unusual Presentation ◽  
Long Bone ◽  
Primary Bone Tumor ◽  
Rare Syndrome ◽  
Weber Syndrome ◽  
Primary Bone

Osteoblastoma is an uncommon primary bone tumor that usually presents as a painful lesion in a long bone or in the spine. Osteoblastoma has been reported only twice in the literature in conjunction with systemic fibromatosis. The authors report the case of an 8-year-old girl with suspected Klippel-Trenaunay-Weber syndrome, a rare syndrome of systemic fibromatosis, who presented with a painless thoracic rib lesion that was found to be an osteoblastoma.

scholarly journals Giant Calvarial Ewing's Sarcoma: A Case Report

2018 ◽  
Vol 79 (04) ◽  
pp. e79-e82
Author(s):  
Buse Sarigul ◽  
Ece Uysal ◽  
İdris Avci ◽  
Halil Peker ◽  
Suat Celik
Keyword(s):  
Case Report ◽  
Bone Tumor ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Total Removal ◽  
Primary Bone Tumor ◽  
Intracranial Involvement ◽  
Primary Bone ◽  
Parietal Bones

AbstractEwing's sarcoma (EWS) is the second most common primary bone tumor seen in children and adolescents, first being osteosarcoma. Skull lesions are seen in 6 to 9% of cases. The tumor tends to reside most frequently on frontal and parietal bones. In the literature, majority of papers on calvarial EWS present cases with intracranial involvement; extracranial extension is reported in only eight cases. The case that we are presenting in this report is a 23-year-old male patient with multiple infiltrations in femur, costal bones, and calvarium which had been diagnosed radiologically and histopathologically as EWS. The calvarial metastasis had reached a very huge size with dimensions of approximately 7.5 × 7.5 × 9.5 cm and was successfully excised totally. Twelve months of follow-up revealed no recurrence in the surgical site showing that total removal of giant cranial EWS may improve morbidity of these patients.

scholarly journals Exposure of primary bone tumor-associated stromal cells to multi-pesticides at low doses and paracrine effects on osteoclast differentiation

Bone Reports ◽  
2020 ◽  
Vol 13 ◽  
pp. 100421
Author(s):  
Valérie Trichet ◽  
Louis-Romée Le Nail ◽  
Régis Brion ◽  
Françoise Rédini ◽  
François Vallette ◽  
...  
Keyword(s):  
Bone Tumor ◽  
Stromal Cells ◽  
Osteoclast Differentiation ◽  
Low Doses ◽  
Paracrine Effects ◽  
Primary Bone Tumor ◽  
Primary Bone

An Uncommon Presentation of a Primary Bone Tumor

2018 ◽  
Vol 40 (7) ◽  
pp. 555-557
Author(s):  
Daniel Koh ◽  
Theodore Lau ◽  
Evonne Teoh ◽  
Kenneth K. Lau
Keyword(s):  
Bone Tumor ◽  
Primary Bone Tumor ◽  
Uncommon Presentation ◽  
Primary Bone

scholarly journals Macrophages in Osteosarcoma Immune Microenvironment: Implications for Immunotherapy

2020 ◽  
Vol 10 ◽  
Author(s):  
Zhong-Wei Luo ◽  
Pan-Pan Liu ◽  
Zhen-Xing Wang ◽  
Chun-Yuan Chen ◽  
Hui Xie
Keyword(s):  
Overall Survival ◽  
Tumor Microenvironment ◽  
Bone Tumor ◽  
Immune Cells ◽  
Therapeutic Approaches ◽  
Immune Microenvironment ◽  
Primary Bone Tumor ◽  
Promising Strategy ◽  
Primary Bone ◽  
Malignant Primary Bone Tumor

Osteosarcoma is a malignant primary bone tumor commonly occurring in children and adolescents. The treatment of local osteosarcoma is mainly based on surgical resection and chemotherapy, whereas the improvement of overall survival remains stagnant, especially in recurrent or metastatic cases. Tumor microenvironment (TME) is closely related to the occurrence and development of tumors, and macrophages are among the most abundant immune cells in the TME. Due to their vital roles in tumor progression, macrophages have gained increasing attention as the new target of tumor immunotherapy. In this review, we present a brief overview of macrophages in the TME and highlight the clinical significance of macrophages and their roles in the initiation and progression of osteosarcoma. Finally, we summarize the therapeutic approaches targeting macrophage, which represent a promising strategy in osteosarcoma therapies.

TNF-Related Apoptosis Inducing Ligand (TRAIL) inhibits primary bone tumor growth and augments survival in a human model ewing sarcoma

Bone ◽  
2008 ◽  
Vol 42 ◽  
pp. S94
Author(s):  
Loic Geffroy ◽  
Damien Chauviere ◽  
Francois Lamoureux ◽  
Gaelle Picarda ◽  
Olivier Delattre ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Bone Tumor ◽  
Ewing Sarcoma ◽  
Human Model ◽  
Primary Bone Tumor ◽  
Primary Bone

Soft tissue hemangioma with adjacent periosteal reaction simulating a primary bone tumor

1996 ◽  
Vol 25 (2) ◽  
pp. 174-177 ◽  
Author(s):  
John L. DeFilippo ◽  
J. S. Yu ◽  
Lawrence Weis ◽  
Joel Lucas
Keyword(s):  
Soft Tissue ◽  
Bone Tumor ◽  
Periosteal Reaction ◽  
Primary Bone Tumor ◽  
Primary Bone
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