A new pattern of lipomatosis of nerve: case report

Lipomatosis of nerve (LN) is a rare disorder of peripheral nerves that produces proliferation of interfascicular adipose tissue. It may be associated with soft-tissue and bony overgrowth within the affected nerve territory. LN has been almost exclusively reported in appendicular peripheral nerves; the median nerve at the wrist and palm is among the most common locations. The authors present a new pattern of LN that shows circumferential proliferation of fat around the epineurium of the nerve. They believe that this case and the two other documented examples in the literature (also affecting cervical and thoracic spinal nerves) share the same new pattern of LN. Defining the full spectrum of adipose lesions of the nerve and establishing a cause-effect relationship with nerve-territory overgrowth disorders may offer options for future management through targeted nerve lesioning.

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Segmental thoracic lipomatosis of nerve with nerve territory overgrowth

Journal of Neurosurgery ◽

10.3171/2013.12.jns13174 ◽

2014 ◽

Vol 120 (5) ◽

pp. 1118-1124 ◽

Cited By ~ 9

Author(s):

Mark A. Mahan ◽

Kimberly K. Amrami ◽

B. Matthew Howe ◽

Robert J. Spinner

Keyword(s):

Peripheral Nerves ◽

Fatty Infiltration ◽

Rare Condition ◽

Spinal Nerves ◽

Fibrolipomatous Hamartoma ◽

Scoliotic Deformity ◽

Lipomatosis Of Nerve ◽

Thoracic Spinal ◽

History Of ◽

Hands And Feet

Lipomatosis of nerve (LN), or fibrolipomatous hamartoma, is a rare condition of fibrofatty enlargement of the peripheral nerves. It is associated with bony and soft tissue overgrowth in approximately one-third to two-thirds of cases. It most commonly affects the median nerve at the carpal tunnel or digital nerves in the hands and feet. The authors describe a patient with previously diagnosed hemihypertrophy of the trunk who had a history of large thoracic lipomas resected during infancy, a thoracic hump due to adipose proliferation within the thoracic paraspinal musculature, and scoliotic deformity. She had fatty infiltration in the thoracic spinal nerves on MRI, identical to findings pathognomonic of LN at better-known sites. Enlargement of the transverse processes at those levels and thickened ribs were also found. This case appears to be directly analogous to other instances of LN with overgrowth, except that this case involved axial nerves rather than the typical appendicular nerves.

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Lipofibromatous hamartoma of a digital branch of the median nerve: a case report and review of the literature

10.22541/au.162644235.51823012/v1 ◽

2021 ◽

Author(s):

Jorge Barraza-Silva ◽

Roberto Berebichez-Fridman ◽

Lilia Corona-Cobian ◽

Laura Bernal-López ◽

Raúl Álvarez-San Martín

Keyword(s):

Adipose Tissue ◽

Case Report ◽

Median Nerve ◽

Carpal Tunnel ◽

Peripheral Nerves ◽

Review Of The Literature ◽

Nerve Enlargement ◽

Lipofibromatous Hamartoma ◽

Uncommon Tumor

Lipofibromatous hamartoma is an uncommon tumor that causes nerve enlargement due to fatty adipose tissue infiltration in peripheral nerves being the median nerve at the carpal tunnel the most commonly affected site, typically associated with macrodactyly. Here we present a case which affected a digital branch of the median nerve

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Massive growth of a meningioma into the brachial plexus and thoracic cavity after intraspinal and supraclavicular resection

Journal of Neurosurgery Spine ◽

10.3171/spi.2002.96.1.0107 ◽

2002 ◽

Vol 96 (1) ◽

pp. 107-111 ◽

Cited By ~ 3

Author(s):

Edward R. Smith ◽

Mark Ott ◽

John Wain ◽

David N. Louis ◽

E. Antonio Chiocca

Keyword(s):

Case Report ◽

Brachial Plexus ◽

Peripheral Nerves ◽

Pleural Cavity ◽

Thoracic Cavity ◽

Review Of The Literature ◽

Spinal Meningioma ◽

Content Type ◽

Massive Growth ◽

Thoracic Spinal

✓ Extracranial meningiomas comprise approximately 2% of all meningiomas. Involvement of peripheral nerves by meningioma, either by a primary tumor or through secondary extension of an intraaxial lesion, is a much rarer entity; there have been only two reported primary brachial plexus meningiomas and one description of secondary involvement of the brachial plexus by extension of an intraaxial lesion. Although thoracic cavity meningiomas have been described in the literature, their pathogenesis is poorly understood. The authors present the case report of a 36-year-old man who was initially treated for a thoracic spinal meningioma that infiltrated the brachial plexus. After resection, progressive and massive growth with infiltration of the brachial plexus and pleural cavity occurred over a 5-year period despite radio- and chemotherapy. The case report is followed by a review of the literature of this rare entity.

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Fibrolipoma of the Buccal Mucosa: A Case Report and Review of the Literature

Case Reports in Pathology ◽

10.1155/2016/5060964 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Masayasu Iwase ◽

Naotaka Saida ◽

Yoko Tanaka

Keyword(s):

Adipose Tissue ◽

Case Report ◽

Soft Tissue ◽

Oral Cavity ◽

Buccal Mucosa ◽

Soft Tissue Neoplasms ◽

Review Of The Literature ◽

Mature Adipose Tissue ◽

Histological Variant

Lipomas are common benign soft tissue neoplasms derived from mature adipose tissue. However, they rarely arise in the oral cavity. Fibrolipoma is a histological variant of lipoma that mainly affects the buccal mucosa and causes functional and cosmetic issues. This article describes the case of a 71-year-old male with a fibrolipoma of the left buccal mucosa and a review of previous articles about fibrolipoma.

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Hexadactyly in all four limbs in a neonate - a case report

Journal of Dhaka Medical College ◽

10.3329/jdmc.v22i2.21547 ◽

2015 ◽

Vol 22 (2) ◽

pp. 219-222 ◽

Cited By ~ 1

Author(s):

Manisha Banerjee ◽

Sajal Kumar Majumdar

Keyword(s):

Congenital Anomaly ◽

Case Report ◽

Soft Tissue ◽

Birth Defects ◽

Medical College ◽

Proper Management ◽

Orthopedic Surgeons ◽

Comprehensive Knowledge ◽

Pediatric Orthopedic ◽

Future Management

Polydactyly or hyperdactyly is a congenital physical anomaly and is a common congenital digital variation affecting the hand and foot. It may present as a range of defects from minor soft tissue duplications to major bony abnormalities. Of the different varieties the post-axial one is the commonest. Polydactyly may appear as isolated or in association with other birth defects. For proper management a comprehensive knowledge of this condition is required for medical experts particularly the pediatric orthopedic surgeons. Here we report a case of hexadactyly (six fingers) in all four limbs of a neonate. This neonate was free from other congenital anomaly. Photograph and radiographs revealed the anatomical abnormalities, which is essential for proper planning of the future management. DOI: http://dx.doi.org/10.3329/jdmc.v22i2.21547 J Dhaka Medical College, Vol. 22, No.2, October, 2013, Page 219-222

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Epithelioid Sarcoma in the Median Nerve of the Hand: A Case Report

Hand ◽

10.1177/15589447211030689 ◽

2021 ◽

pp. 155894472110306

Author(s):

Pilar Uceda ◽

Manuel Zafra ◽

Ricardo González-Cámpora ◽

Carmen Ruiz-Bonilla

Keyword(s):

Case Report ◽

Local Recurrence ◽

Median Nerve ◽

Reconstructive Surgery ◽

Peripheral Nerves ◽

Epithelioid Sarcoma ◽

Radical Resection ◽

Metastatic Dissemination ◽

The Right

Epithelioid sarcoma of the peripheral nerves is extremely rare. We present a case concerning the median nerve of the right hand in a 35-year-old woman who was treated with radical resection, reconstructive surgery, and chemotherapy. After 2 years of follow-up, there is no evidence of local recurrence or metastatic dissemination.

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Carpal Tunnel Syndrome Caused by a Simple Ganglion

HAND ◽

10.1016/s0072-968x(81)80057-5 ◽

1981 ◽

Vol os-13 (2) ◽

pp. 164-166 ◽

Cited By ~ 15

Author(s):

F. J. Harvey ◽

J. S. Bosanquet

Keyword(s):

Case Report ◽

Carpal Tunnel Syndrome ◽

Median Nerve ◽

Ulnar Nerve ◽

Carpal Tunnel ◽

Peripheral Nerves ◽

Nerve Compression ◽

Median Nerve Compression ◽

Deep Branch ◽

Tunnel Syndrome

The compression of peripheral nerves by simple ganglia is a well recognized and documented clinical entity. It has been reported where ganglia have been associated with the ankle, knee and elbow joints (D. M. Brooks, 1952). It is probably best known in compression of the deep branch of the ulnar nerve in the wrist, first described by Seddon (Seddon H. J. 1952). Median nerve compression at the wrist, however, that causes a carpal tunnel syndrome would appear to be well recognized but poorly documented. Brooks (1952) described a case and until now, no others have been recorded in the literature. This case report describes such median nerve involvement with some interesting features.

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