Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report
2019 ◽
Vol 131
(6)
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pp. 1773-1779
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Keyword(s):
The authors report on a 57-year-old woman in whom progression to brain death occurred on day 9 after aneurysmal subarachnoid hemorrhage without evidence of significant brain edema or vasospasm. Neuromonitoring demonstrated that brain death was preceded by a series of cortical spreading depolarizations that occurred in association with progressive hypoxic episodes. The depolarizations induced final electrical silence in the cortex and ended with a terminal depolarization that persisted > 7 hours. To the authors’ knowledge, this is the first report of terminal spreading depolarization in the human brain prior to clinical brain death and major cardiopulmonary failure.
2014 ◽
Vol 54
(3)
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pp. 231-235
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Keyword(s):
2011 ◽
Vol 32
(2)
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pp. 201-202
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2010 ◽
Vol 25
(1)
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pp. 53-64
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