Cerebral vasospasm evaluated by transcranial Doppler ultrasonography at different intracranial pressures

1991 ◽  
Vol 75 (5) ◽  
pp. 752-758 ◽  
Author(s):  
Jürgen Klingelhöfer ◽  
Dirk Sander ◽  
Manfred Holzgraefe ◽  
Christian Bischoff ◽  
Bastian Conrad

✓ The present study evaluates the interdependence of clinical stage, cerebral vasospasm, intracranial pressure (ICP), and transcranial Doppler ultrasonographic parameters. The mean flow velocity of blood in the middle cerebral artery and the index of cerebral circulatory resistance as a measure of the peripheral vascular flow resistance were determined in 76 patients with spontaneous subarachnoid hemorrhage. The ICP was measured using an epidural transducer in 41 patients. There was no case in which both high ICP and a high mean flow velocity were observed simultaneously. The investigations led to the following conclusions. 1) In patients with a resistance index of less than 0.5, changes in the mean flow velocity seem to reflect sufficiently the actual severity and time course of vasospasm. 2) During the time course of vasospasm, an increase in the resistance index above values of 0.6 with a simultaneously decreased mean flow velocity indicates a rise in ICP rather than a reduction in vasospasm. 3) With a pronounced increase in ICP, evaluation of the severity and time course of vasospasm by transcranial Doppler ultrasonography based solely upon the mean flow velocity can lead to false-negative results.

Author(s):  
Christoph Jörg ◽  
Michael Wagner ◽  
Thomas Sattelmayer

The thermoacoustic stability of gas turbines depends on a balance of acoustic energy inside the engine. While the flames produce acoustic energy, other areas like the impingement cooling system contribute to damping. In this paper, we investigate the damping potential of an annular impingement sleeve geometry embedded into a realistic environment. A cold flow test rig was designed to represent real engine conditions in terms of geometry, and flow situation. High quality data was delivered by six piezoelectric dynamic pressure sensors. Experiments were carried out for different mean flow velocities through the cooling holes. The acoustic reflection coefficient of the impingement sleeve was evaluated at a downstream reference location. Further parameters investigated were the number of cooling holes, and the geometry of the chamber surrounding the impingement sleeve. Experimental results show that the determining parameter for the reflection coefficient is the mean flow velocity through the impingement holes. An increase of the mean flow velocity leads to significantly increased damping, and to low values of the reflection coefficient.


Owing to observational difficulties the distinction between a ‘suspended’ load of solids transported by a stream and a ‘ bed-load ’ has long remained undefined. Recently, however, certain critical experiments have thrown much light on the nature of bed-load transport. In particular, it has been shown that bed-load transport, by saltation, occurs in the absence of fluid turbulence and must therefore be due to a separate dynamic process from that of transport in suspension by the internal eddy motion of a turbulent fluid. It has been further shown that the forward motion of saltating solids is opposed by a frictional force of the same order as the immersed weight of the solids, the friction coefficient approximating to that given by the angle of slip. The maintenance of steady motion therefore requires a predictable rate of energy dissipation by the transporting fluid. The fluid thrust necessary to maintain the motion is shown to be exerted by virtue of a mean slip velocity which is predictable in the same way as, and approxim ates to, the terminal fall velocity of the solid. The mean thrust, and therefore the transport rate of saltating solids, are therefore predictable in terms of the fluid velocity close to the bed, at a distance from it, within the saltation zone, of a ‘centre of fluid thrust’ analogous to the ‘centre of pressure’. This velocity, which is not directly measurable in water streams, can be got from a knowledge of stream depth and mean flow velocity. Thus a basic energy equation is obtained relating the rate of transporting work done to available fluid transporting power. This is shown to be applicable to the transport both of wind-blown sand, and of water-driven solids of all sizes and larger than that of medium sand. Though the mean flow velocity is itself unpredictable, the total stream power, which is the product of this quantity times the bed shear stress, is readily measurable. But since the mean flow velocity is an increasing function of flow depth, the transport of solids expressed in terms of total stream power must decrease with increasing flow depth/grain size ratio. This considerable variation with flow depth has not been previously recognised. It explains the gross inconsistencies found in the existing experimental data. The theoretical variation is shown to approximate very closely to that found in recent critical experiments in which transport rates were measured at different constant flow depths. The theory, which is largely confirmed by these and other earlier experiments, indicates that suspension by fluid turbulence of mineral solids larger than those of medium sands does not become appreciable until the bed shear stress is increased to a value exceeding 12 times its threshold value for the bed material considered. This range of unsuspended transport decreases rapidly, however, as the grain size is reduced till, at a certain critical size, suspension should occur at the threshold of bed movement.


2020 ◽  
Vol 17 (5) ◽  
pp. 1221-1236
Author(s):  
Hui-Huang Fang ◽  
Shu-Xun Sang ◽  
Shi-Qi Liu

Abstract The three-dimensional (3D) structures of pores directly affect the CH4 flow. Therefore, it is very important to analyze the 3D spatial structure of pores and to simulate the CH4 flow with the connected pores as the carrier. The result shows that the equivalent radius of pores and throats are 1–16 μm and 1.03–8.9 μm, respectively, and the throat length is 3.28–231.25 μm. The coordination number of pores concentrates around three, and the intersection point between the connectivity function and the X-axis is 3–4 μm, which indicate the macro-pores have good connectivity. During the single-channel flow, the pressure decreases along the direction of CH4 flow, and the flow velocity of CH4 decreases from the pore center to the wall. Under the dual-channel and the multi-channel flows, the pressure also decreases along the CH4 flow direction, while the velocity increases. The mean flow pressure gradually decreases with the increase of the distance from the inlet slice. The change of mean flow pressure is relatively stable in the direction horizontal to the bedding plane, while it is relatively large in the direction perpendicular to the bedding plane. The mean flow velocity in the direction horizontal to the bedding plane (Y-axis) is the largest, followed by that in the direction horizontal to the bedding plane (X-axis), and the mean flow velocity in the direction perpendicular to the bedding plane is the smallest.


2009 ◽  
Vol 111 (1) ◽  
pp. 22-27 ◽  
Author(s):  
Satoshi Tateshima ◽  
Kazuo Tanishita ◽  
Yasuhiro Hakata ◽  
Shin-ya Tanoue ◽  
Fernando Viñuela

Object Development of a flexible self-expanding stent system and stent-assisted coiling technique facilitates endovascular treatment of wide-necked brain aneurysms. The hemodynamic effect of self-expandable stent placement across the neck of a brain aneurysm has not been well documented in patient-specific aneurysm models. Methods Three patient-specific silicone aneurysm models based on clinical images were used in this study. Model 1 was constructed from a wide-necked internal carotid artery–ophthalmic artery aneurysm, and Models 2 and 3 were constructed from small wide-necked middle cerebral artery aneurysms. Neuroform stents were placed in the in vitro aneurysm models, and flow structures were compared before and after the stent placements. Flow velocity fields were acquired with particle imaging velocimetry. Results In Model 1, a clockwise, single-vortex flow pattern was observed in the aneurysm dome before stenting was performed. There were multiple vortices, and a very small fast flow stream was newly formed in the aneurysm dome after stenting. The mean intraaneurysmal flow velocity was reduced by ~ 23–40%. In Model 2, there was a clockwise vortex flow in the aneurysm dome and another small counterclockwise vortex in the tip of the aneurysm dome before stenting. The small vortex area disappeared after stenting, and the mean flow velocity in the aneurysm dome was reduced by 43–64%. In Model 3, a large, counterclockwise, single vortex was seen in the aneurysm dome before stenting. Multiple small vortices appeared in the aneurysm dome after stenting, and the mean flow velocity became slower by 22–51%. Conclusions The flexible self-expandable stents significantly altered flow velocity and also flow structure in these aneurysms. Overall flow alterations by the stent appeared favorable for the long-term durability of aneurysm embolization. The possibility that the placement of a low-profile self-expandable stent might induce unfavorable flow patterns such as a fast flow stream in the aneurysm dome cannot be excluded.


1992 ◽  
Vol 2 (6) ◽  
pp. 372-377 ◽  
Author(s):  
Carlos Cantu ◽  
Masahiro Yasaka ◽  
Takashi Tsuchiya ◽  
Takenori Yamaguchi

Sign in / Sign up

Export Citation Format

Share Document