scholarly journals Spinal Cord Injury after Blunt Cervical Spine Trauma: Correlation of Soft-Tissue Damage and Extension of Lesion

2013 ◽  
Vol 35 (5) ◽  
pp. 1029-1034 ◽  
Author(s):  
R. Martinez-Perez ◽  
I. Paredes ◽  
S. Cepeda ◽  
A. Ramos ◽  
A. M. Castano-Leon ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cervical Spine ◽  
Soft Tissue ◽  
Tissue Damage ◽  
Soft Tissue Damage ◽  
Cervical Spine Trauma ◽  
Spine Trauma ◽  
Cord Injury

scholarly journals Blunt cervical spine trauma as a cause of spinal cord injury and delayed cortical blindness

Spinal Cord ◽  
2006 ◽  
Vol 45 (10) ◽  
pp. 687-689 ◽  
Author(s):  
M T McCormick ◽  
H K Robinson ◽  
I Bone ◽  
A N McLean ◽  
D B Allan
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cervical Spine ◽  
Cortical Blindness ◽  
Cervical Spine Trauma ◽  
Spine Trauma ◽  
Cord Injury

scholarly journals New Grading System for Cervical Paraspinal Soft Tissue Damage After Traumatic Cervical Spinal Cord Injury Without Major Fracture Based on the Short-T1 Inversion Recovery Mid-Sagittal MRI for Prediction of Neurological Improvements: The STIR-MRI Grade

2021 ◽  
pp. 219256822110101
Author(s):  
Kotaro Aburakawa ◽  
Toru Yokoyama ◽  
Kazunari Takeuchi ◽  
Takuya Numasawa ◽  
Kanichiro Wada ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Soft Tissue ◽  
Tissue Damage ◽  
Cervical Spinal Cord ◽  
Cervical Spinal Cord Injury ◽  
Soft Tissue Damage ◽  
Cord Injury ◽  
Nuchal Ligament

Study Design: Retrospective cohort study. Objective: To develop a grading method for cervical paraspinal soft tissue damage after cervical spinal cord injury (CSCI) without major fracture based on the short T1 inversion recovery (STIR) mid-sagittal magnetic resonance image (MRI) for prediction of neurological improvements. Methods: This study included 34 patients with CSCI without major fracture, treated conservatively for at least 1 year and graded using the STIR-MRI Grade. This system consists of anterior grades; A0: no high-intensity area (HIA), A1: linear HIA, and A2: fusiform HIA, and posterior grades; P0: no HIA, P1: HIA not exceeding the nuchal ligament, and P2: HIA exceeding the nuchal ligament, within 24 hours postinjury. The American Spinal Injury Association impairment scale (AIS) and the Japanese Orthopedic Association (JOA) scores were examined. Results: Anterior grades were not significantly correlated with the AIS and JOA score. At both injury and final follow-up, the AIS in P2 patients was significantly more severe ( P = 0.007, P = 0.015, respectively) than that in P0 patients. At the injury, the AIS in P2 patients was significantly more severe ( P = 0.008) than that in P1 patients. Among P2 patients only, the JOA score at the injury (1.4 points) did not improve by the final follow-up (3.9 points). The final follow-up JOA score (3.9 points) in P2 patients was significantly lower than that (13.6 points) in P0 patients ( P = 0.016). Conclusions: Grade P2 led to poor neurological outcomes. The STIR-MRI Grade is a prognostic indicator for neurological improvements past-CSCI.

scholarly journals Cervical Spine Trauma and Spinal Cord Injury Recommendations of WFNS Spine Committee

Neurospine ◽  
2020 ◽  
Vol 17 (4) ◽  
pp. 704-707
Author(s):  
Mehmet Zileli ◽  
Nikolay Konovalov ◽  
Salman Sharif
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cervical Spine ◽  
Cervical Spine Trauma ◽  
Spine Trauma ◽  
Cord Injury

Soft-Tissue Damage and Segmental Instability in Adult Patients With Cervical Spinal Cord Injury Without Major Bone Injury

Spine ◽  
2012 ◽  
Vol 37 (25) ◽  
pp. E1560-E1566 ◽  
Author(s):  
Takeshi Maeda ◽  
Takayoshi Ueta ◽  
Eiji Mori ◽  
Itaru Yugue ◽  
Osamu Kawano ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Soft Tissue ◽  
Tissue Damage ◽  
Cervical Spinal Cord ◽  
Cervical Spinal Cord Injury ◽  
Adult Patients ◽  
Segmental Instability ◽  
Bone Injury ◽  
Cord Injury

scholarly journals Local Serpin Treatment via Chitosan-Collagen Hydrogel after Spinal Cord Injury Reduces Tissue Damage and Improves Neurologic Function

2020 ◽  
Vol 9 (4) ◽  
pp. 1221 ◽  
Author(s):  
Jacek M. Kwiecien ◽  
Liqiang Zhang ◽  
Jordan R. Yaron ◽  
Lauren N. Schutz ◽  
Christian J. Kwiecien-Delaney ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Tissue Damage ◽  
Low Dose ◽  
Dorsal Column ◽  
Neurological Deficits ◽  
Sustained Delivery ◽  
Post Surgery ◽  
Cord Injury ◽  
Anti Inflammatory

Spinal cord injury (SCI) results in massive secondary damage characterized by a prolonged inflammation with phagocytic macrophage invasion and tissue destruction. In prior work, sustained subdural infusion of anti-inflammatory compounds reduced neurological deficits and reduced pro-inflammatory cell invasion at the site of injury leading to improved outcomes. We hypothesized that implantation of a hydrogel loaded with an immune modulating biologic drug, Serp-1, for sustained delivery after crush-induced SCI would have an effective anti-inflammatory and neuroprotective effect. Rats with dorsal column SCI crush injury, implanted with physical chitosan-collagen hydrogels (CCH) had severe granulomatous infiltration at the site of the dorsal column injury, which accumulated excess edema at 28 days post-surgery. More pronounced neuroprotective changes were observed with high dose (100 µg/50 µL) Serp-1 CCH implanted rats, but not with low dose (10 µg/50 µL) Serp-1 CCH. Rats treated with Serp-1 CCH implants also had improved motor function up to 20 days with recovery of neurological deficits attributed to inhibition of inflammation-associated tissue damage. In contrast, prolonged low dose Serp-1 infusion with chitosan did not improve recovery. Intralesional implantation of hydrogel for sustained delivery of the Serp-1 immune modulating biologic offers a neuroprotective treatment of acute SCI.

The Torg-Pavlov ratio for the prediction of acute spinal cord injury after a minor trauma to the cervical spine

2013 ◽  
Vol 13 (6) ◽  
pp. 605-612 ◽  
Author(s):  
Nikolaus Aebli ◽  
Anina G. Wicki ◽  
Tabea B. Rüegg ◽  
Nassos Petrou ◽  
Heidrun Eisenlohr ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cervical Spine ◽  
Acute Spinal Cord Injury ◽  
Minor Trauma ◽  
Cord Injury ◽  
A Minor
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