<p><em>Zooglider</em> is an autonomous buoyancy-driven ocean glider designed and built by the Instrument Development Group at Scripps. <em>Zooglider</em> includes a low power camera with a telecentric lens for shadowgraph imaging and two custom active acoustics echosounders (operated at 200/1000 kHz).&#160; A passive acoustic hydrophone records vocalizations from marine mammals, fishes, and ambient noise.&#160; The imaging system (<em>Zoocam</em>) quantifies zooplankton and &#8216;marine snow&#8217; as they flow through a sampling tunnel within a well-defined sampling volume. Other sensors include a pumped Conductivity-Temperature-Depth probe and Chl-<em>a</em> fluorometer.&#160; An acoustic altimeter permits autonomous navigation across regions of abrupt seafloor topography, including submarine canyons and seamounts. &#160;Vertical sampling resolution is typically 5 cm, maximum operating depth is ~500 m, and mission duration up to 50 days.&#160; Adaptive sampling is enabled by telemetry of measurements at each surfacing.&#160; Our post-deployment processing methodology classifies the optical images using advanced Deep Learning methods that utilize context metadata.&#160; <em>Zooglider</em> permits in situ measurements of mesozooplankton and marine snow - and their natural, three dimensional orientation - in relation to other biotic and physical properties of the ocean water column. &#160;<em>Zooglider</em> resolves micro-scale patches, which are important for predator-prey interactions and biogeochemical cycling.&#160;</p><p>&#160;</p>