Cationic copolymerisation of cholesterol vinyl ether with N-allenylpyrrolidone; a route to pharmacologically promising oligomers
2019 ◽
Vol 485
(6)
◽
pp. 697-700
◽
Keyword(s):
Cationic copolymerization of cholesterol vinyl ether with N-allenylpyrrolidone yielded co-oligomers with molecular mass of 1200-2100. The polymerization of N-allenylpyrrolidone involves both 1,2- and 2,3-positions of the allenyl substituent to give four types of units as a result of prototropic isomerization of the initially formed structures. In the developed method, the composition of co-oligomers can be controlled and, hence, their hydrophilic/hydrophobic balance, solubility, and membranotropic properties can also be controlled to change the potential biological activity of the products.
Keyword(s):
2008 ◽
Vol 183
(6)
◽
pp. 1323-1343
◽
2012 ◽
Vol 5
(2)
◽
pp. 127-130
◽
1998 ◽
Vol 133
(1)
◽
pp. 13-20