Deformation of the left heart chambers in hypertensive postmenopausal women, depending on the presence of left ventricular hypertrophy and left atrium dilation

The aim – to assess the longitudinal deformation (strain) of the left heart chambers in postmenopausal women with essential hypertension (EH), depending on the presence of left ventricular hypertrophy (LVH) and left atrial (LA) dilation. Materials and methods. The study involved 126 postmenopausal women: 100 patients with EH I–II stages of the main group and 26 practically healthy women of the comparison group. Patients with EH were divided into two groups: 32 patients without structural changes of the myocardium and 68 women with LVH and/or LA dilation. In all patients we performed ambulatory blood pressure monitoring, standard transthoracic echocardiography and speckle-tracking echocardiography. The global longitudinal strain (GLS) of LV and deformation of the endocardial (endo), middle (mid) and epicardial (epi) layers of myocardium were analyzed. Analysis of LA deformation was performed using two (from the beginning of the R-wave and from the apex of the R-wave) variants of ECG-synchronization. The LA longitudinal strain (LS) was evaluated in reservoir and contraction phase in two positions with the calculation of the GLS LA. Results and discussion. We found changes in LV multilayer deformation as LS decreasing in the endocardial, middle and epicardial layers in hypertensive patients in the early stages of disease, even before the development of LVH. Damage of LA deformation preceded its dilation. Both types of ECG-synchronization showed a statistically significant decrease of LA strain in the reservoir phase in all hypertensive patients in comparison with healthy women. A decreasing LA GLS in women with EH and structurally normal heart compared to the healthy group was detected only by using ECG-synchronization with R-wave, which is considered more universal. Conclusion. A decrease of LA and LV LS in postmenopausal women is recorded even before the development of LVH and LA dilation. The LV LS became lower in all layers of myocardium – from endocardial to epicardial. Changes in the LA LS in postmenopausal women with EH begin with a damage of reservoir phase even with normal size of LA and a LV myocardial mass index.

Download Full-text

P286 Inverse relation between systolic blood pressure variability and global longitudinal strain in patients with Parkinson"s disease and autonomic dysfunction

European Heart Journal - Cardiovascular Imaging ◽

10.1093/ehjci/jez319.140 ◽

2020 ◽

Vol 21 (Supplement_1) ◽

Author(s):

G Caminiti ◽

V D"antoni ◽

V Morsella ◽

M Torti ◽

P Grassini ◽

...

Keyword(s):

Blood Pressure ◽

Autonomic Dysfunction ◽

Longitudinal Strain ◽

Systolic Function ◽

Blood Pressure Monitoring ◽

Global Longitudinal Strain ◽

Left Ventricular Systolic Function ◽

Left Ventricular ◽

S Wave ◽

Hypertensive Patients

Abstract Background Parkinson"s disease (PD) patients often present cardiac blood pressure (BP) derangement as a result of autonomic dysfunction. However their echocardiography pattern have been poorly investigated yet . Study aim: to evaluate the correlation between indices of left ventricular function ad 24/h blood pressure pattern in patients with PD Methods We evaluated 20 patients with diagnosed PD and autonomic dysfunction and 15 hypertensive age-matched subjects. All patients performed 24/h blood pressure monitoring (ABPM) and echocardiography. Left ventricular systolic function was evaluated through ejection fraction (EF), tissue doppler S wave and global longitudinal strain (GLS). BP variability (BPV) was evaluated through average real variability. Results GLS (17.6 vs 22.8; p = 0.04) was reduced in the PD group compared to hypertensive patients. Conversely EF and S wave was similar between the two groups. Patients with PD had an inverse significant correlation between GLS and 24/h systolic BPV (r= -0.64; p = 0.003) and a trend through significance between S wave and systolic BPV (r= -0.31; p = 0.07). sNocturnal diastolic BP was inversely related to GLS (r= -0.44; p = 0.001) . There were no correlation between GLS and BPV and values in hypertensive patients. Conclusions In PD patients GLS is related to indices of poor BP control. GLS appears to be an early detector of LV dysfunction in patients with PD and autonomic dysfunction.

Download Full-text

C017 Ambulatory blood pressure monitoring: Randomized study of hypertensive patients with left ventricular hypertrophy

American Journal of Hypertension ◽

10.1016/s0895-7061(97)90892-x ◽

1998 ◽

Vol 11 (4) ◽

pp. 52A

Author(s):

C MACHADO

Keyword(s):

Blood Pressure ◽

Left Ventricular Hypertrophy ◽

Ambulatory Blood Pressure Monitoring ◽

Ambulatory Blood Pressure ◽

Ventricular Hypertrophy ◽

Blood Pressure Monitoring ◽

Randomized Study ◽

Left Ventricular ◽

Pressure Monitoring ◽

Hypertensive Patients

Download Full-text

Role of global longitudinal strain in discriminating variant forms of left ventricular hypertrophy and predicting mortality

10.5152/anatoljcardiol.2021.21940 ◽

2021 ◽

Vol 25 (12) ◽

pp. 863-871

Author(s):

Pelin Karaca Özer ◽

◽

Elif Ayduk Gövdeli ◽

Berat Engin ◽

Adem Atıcı ◽

...

Keyword(s):

Left Ventricular Hypertrophy ◽

Longitudinal Strain ◽

Ventricular Hypertrophy ◽

Global Longitudinal Strain ◽

Left Ventricular

Download Full-text

Ratio of Transmitral Early-Diastolic Velocity to Global Longitudinal Strain Accurately Estimates Filling Pressure Regardless of Left Ventricular Hypertrophy

Journal of Cardiac Failure ◽

10.1016/j.cardfail.2015.08.104 ◽

2015 ◽

Vol 21 (10) ◽

pp. S162

Author(s):

Taichi Hayashi ◽

Satoshi Yamada ◽

Hiroyuki Iwano ◽

Masahiro Nakabachi ◽

Hirotsugu Yamada ◽

...

Keyword(s):

Left Ventricular Hypertrophy ◽

Longitudinal Strain ◽

Ventricular Hypertrophy ◽

Global Longitudinal Strain ◽

Left Ventricular ◽

Filling Pressure ◽

Diastolic Velocity

Download Full-text

Are there any particularities of ambulatory blood pressure monitoring values in hypertensive patients with resistant left ventricular hypertrophy?

American Journal of Hypertension ◽

10.1016/s0895-7061(02)02715-2 ◽

2002 ◽

Vol 15 (4) ◽

pp. A163

Author(s):

Z KOBALAVA

Keyword(s):

Blood Pressure ◽

Left Ventricular Hypertrophy ◽

Ambulatory Blood Pressure Monitoring ◽

Ambulatory Blood Pressure ◽

Ventricular Hypertrophy ◽

Blood Pressure Monitoring ◽

Left Ventricular ◽

Pressure Monitoring ◽

Hypertensive Patients

Download Full-text

Left ventricular dyssynchrony and 2D and 3D global longitudinal strain for differentiating physiological and pathological left ventricular hypertrophy

Archives of Cardiovascular Diseases ◽

10.1016/j.acvd.2016.11.003 ◽

2017 ◽

Vol 110 (6-7) ◽

pp. 403-412 ◽

Cited By ~ 11

Author(s):

Julien Ternacle ◽

Camille Bremont ◽

Thomas d’Humieres ◽

Laureline Faivre ◽

Huy Long Doan ◽

...

Keyword(s):

Left Ventricular Hypertrophy ◽

Longitudinal Strain ◽

Ventricular Hypertrophy ◽

Global Longitudinal Strain ◽

Left Ventricular ◽

Left Ventricular Dyssynchrony ◽

Ventricular Dyssynchrony ◽

2D And 3D

Download Full-text

Correlation between Global Longitudinal Strain and QRS Voltage on Electrocardiogram in Patients with Left Ventricular Hypertrophy

Echocardiography ◽

10.1111/echo.12362 ◽

2013 ◽

Vol 31 (3) ◽

pp. 325-334 ◽

Cited By ~ 3

Author(s):

Carmen C. Beladan ◽

Bogdan A. Popescu ◽

Andreea Calin ◽

Monica Rosca ◽

Florin Matei ◽

...

Keyword(s):

Left Ventricular Hypertrophy ◽

Longitudinal Strain ◽

Ventricular Hypertrophy ◽

Global Longitudinal Strain ◽

Left Ventricular

Download Full-text

Left ventricular longitudinal strain in professional athletes, a useful tool to detect an athletes hearts?

European Heart Journal ◽

10.1093/ehjci/ehaa946.0101 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

Y Bewarder ◽

S Kulenthiran ◽

O Schaefer ◽

L Lauder ◽

C Ukena ◽

...

Keyword(s):

Left Ventricular Hypertrophy ◽

Endurance Exercise ◽

Longitudinal Strain ◽

Ventricular Hypertrophy ◽

Global Longitudinal Strain ◽

Left Ventricular ◽

Soccer Players ◽

Professional Athletes ◽

Healthy Controls ◽

Professional Soccer

Abstract Background Professional cyclists frequently present with physiological adaptations to endurance exercise with an increase in left ventricular wall thickness and mass. Global longitudinal strain (GLS) is an early and sensitive echocardiographic method to detect left ventricular dysfunction. However, it is unclear whether GLS is able to differentiate between athlete's hearts or different pathological conditions of left ventricular hypertrophy. Methods A total of 87 professional athletes (37 professional cyclists, 29 professional soccer players, and 21 professional handball players) were compared to 125 patients with different forms of left ventricular hypertrophy (17 hypertrophic obstructive cardiomyopathy (HOCM), 36 hypertensive heart disease (HHD), 35 severe aortic valve stenosis (AVS); 37 untrained individuals served as controls. Examinations were performed between October 2018 to October 2019. All subjects underwent echocardiographic examination, including GLS. Results In all 212 participants/patients included a preserved ejection fraction >50% (mean 61±7%) was detected. Left ventricular mass index (LVMI) in professional cyclists (165.5±37.1 g/m2) was increased when compared to professional soccer players (97.3±12.4 g/m2, p<0.001), professional handball players (92.2±15.8 g/m2, p<0.001) and healthy controls (94.3±20.7 g/m2, p<0.001), as well as to patients with HHD (129.2±30.0 g/m2, p<0.001), or AVS (140.1±35.4 g/m2, p=0.064), but not to patients with HOCM (159.7±39.4 g/m2, p=0.64). Professional cyclists (−21.0±3.5%) achieved higher average GLS values than professional soccer (−18.4 ± %, p=0.004) or handball players (−18.4 ± %, p=0.021), healthy controls (−19.0±3.0%, p=0.008), HOCM (−15.0±6.5%, p<0.001), HHD (−13.8±5.9%, p<0.001), and AVS (−16.0±7.0%, p<0.001) (Figure 1). Conclusion In professional cyclists, higher LVMI and average GLS values were detected compared to professional soccer and handball players with lower excessive endurance exercise, as well as untrained healthy controls. Average GLS can help to differentiate between athletes' hearts in professional cyclists compared to pathologic patterns in different diseases characterized by left ventricular hypertrophy with elevated LVMI. Figure 1 Funding Acknowledgement Type of funding source: None

Download Full-text

Assessment of the study of longitudinal systolic function by 2D strain in hypertensive patients

European Heart Journal - Cardiovascular Imaging ◽

10.1093/ehjci/jeab090.125 ◽

2021 ◽

Vol 22 (Supplement_2) ◽

Author(s):

N Taleb Bendiab ◽

S Benkhedda ◽

A Meziane Tani

Keyword(s):

General Population ◽

Left Ventricular Hypertrophy ◽

Diastolic Function ◽

Longitudinal Strain ◽

Ventricular Hypertrophy ◽

Systolic Function ◽

Left Ventricular ◽

Systemic Hypertension ◽

Hypertensive Patients ◽

2D Strain

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): University Hospital Center of Tlemcen Introduction Hypertension is a well-established risk factor for cardiovascular disease. It causes left ventricular (LV) pressure overload, and, changes in cardiac geometry and LV hypertrophy(LVH). LVH as well as patterns of abnormal geometry have been associated with adverse outcomes. Global longitudinal strain (GLS) has been used to detect early subclinical myocardial dysfunction in a broad spectrum of cardiac conditions and thereby provides a novel approach for LV risk assessment in patients with hypertension. Purpose This study is intended to assess the clinical and echocardiographic factors associated with and predictive for early impairment of left ventricular function as assessed using GLS evaluation in hypertensive patients. Methods Cross-sectional descriptive study, with a total number of 130 hypertensive and with the objective of evaluating the study of longitudinal function by 2D strain in patients with systemic hypertension with preserved LVEF and the determination of predictors the decrease GLS in this population. A complete study echo cardiographic, including LVEF biplane Simpson method, calculation of left ventricular mass indexed and relative parietal thickness to differentiate the eccentric and concentric LVH, analysis diastolic function and finally the study of longitudinal strain of the LV by the speckle tracking technique (calculation of GLS) to seek a possible decline in the GLS and establish a possible correlation between this drop and power and LVH the diagnosis of subclinical hypertensive heart disease. Results The prevalence of left ventricular hypertrophy (LVH) was found in (66%) in this population. half of the patients (49%) presented a concentric hypertrophy, It was clearly noted that 73%of the patients had a relative wall thickness (RWT)>0.42. Alterations in diastolic function were detected in 89% of the group, 18% had severe diastolic dysfunction with elevation in filling pressure. Analysis of the longitudinal systolic function of the left ventricle took the average GLS as a reference value. The mean GLS was found to be -16.9 ± 3.2%, within a range between -25% and-11.6%. Low GLS values (>-17%) were found in 45.5% of the general population. In particular, 34.4% of the patients had no left ventricular hypertrophy (LVH) and 50.7% of them presented LVH. The average systolic and diastolic blood pressures, taken at the time of echocardiographic analysis, were found higher in the subgroup of hypertensive patients with low GLS. Very low GLS values (>-13%) were found in 11% of the general population. Statistical analysis revealed significant correlation between the decrease in GLS and diabetes the values of blood pressure and elevated filling pressures. Conclusion The evaluation of longitudinal systolic function provides new insight of myocardial function in hypertension that could improve the pathophysiological understanding and identify high-risk heart failure patients eligible for preventive strategies.

Download Full-text