Langerhans cell histiocytosis of an intramammary lymph node in an 18-year-old woman

A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion. The patient was operated on. The pathological diagnosis was reported as papillary thyroid carcinoma. The immunohistochemical examination showed multiple foci of Langerhans cell histiocytosis involving both lobes. The patient died due to cardiac arrest with respiratory causes in the early postoperative period. Langerhans cell histiocytosis is a rare primary condition which involves abnormal clonal proliferation of Langerhans cells in various tissues and organs. Thyroid involvement is infrequently seen. Although the etiology is unknown, genetic components may be linked to the disease. It is also associated with a family history of thyroid disease. Papillary thyroid carcinoma is the most common malignant epithelial tumor of the thyroid gland. Langerhans cell histiocytosis presenting with papillary thyroid carcinoma is rare. The privilege of our case is langerhans cell histiocytosis of the thyroid with multiple cervical lymph node involvement accompanying cervical lymph node metastatic thyroid papillary carcinoma.

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Pancreatic hamartoma with Langerhans cell histiocytosis in a draining lymph node

Histopathology ◽

10.1046/j.1365-2559.1998.0491c.x ◽

1998 ◽

Vol 33 (5) ◽

pp. 485-487 ◽

Cited By ~ 18

Author(s):

S S Wu ◽

H I Vargas ◽

S W French

Keyword(s):

Lymph Node ◽

Langerhans Cell Histiocytosis ◽

Langerhans Cell ◽

Draining Lymph Node

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Pulmonary Langerhans cell histiocytosis with inguinal abscess: Unusual presentation

Proceedings of Singapore Healthcare ◽

10.1177/2010105819900905 ◽

2020 ◽

Vol 29 (1) ◽

pp. 64-66

Author(s):

Kamarul Naim Mohd Hirmizi ◽

Nurul Yaqeen Mohd Esa ◽

Mardiana Abdul Aziz ◽

Nor Salmah Bakar ◽

Mohammad Hanafiah

Keyword(s):

Lymph Node ◽

Langerhans Cell Histiocytosis ◽

Respiratory Symptoms ◽

Inguinal Lymph Node ◽

Langerhans Cell ◽

Histopathological Analysis ◽

Intermittent Fever ◽

Cystic Lung ◽

Pulmonary Langerhans Cell Histiocytosis ◽

History Of

We report a case of a 30-year-old man who was treated as recurrent right inguinal abscess following a 2-month history of right inguinal swelling and intermittent fever with no respiratory symptoms. Resection of his right inguinal lymph node and the histopathological analysis revealed the diagnosis of Langerhans cell histiocytosis. In addition, the CT of the thorax showed presence of bilateral cystic lung changes consistent with pulmonary Langerhans cell histiocytosis.

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A Case of Unicentric Castleman Disease and Langerhans Cell Histiocytosis: Two Entities in One Lymph Node

Clinical Laboratory ◽

10.7754/clin.lab.2018.180547 ◽

2018 ◽

Vol 64 (11+12/2018) ◽

Author(s):

Xiaoyun Liu ◽

Lingling Liu ◽

Ling Zhang ◽

Mi Zhuo ◽

Ruozhi Xiao ◽

...

Keyword(s):

Lymph Node ◽

Langerhans Cell Histiocytosis ◽

Castleman Disease ◽

Langerhans Cell

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Pulmonary Langerhans Cell Histiocytosis Diagnosed in a Cervical Lymph Node

Acta Cytologica ◽

10.1159/000325188 ◽

2010 ◽

Vol 54 (4) ◽

pp. 618-622 ◽

Cited By ~ 1

Author(s):

Richard T. Scuderi ◽

Samir S. Makani ◽

Colleen L. Channick ◽

John W. Renner ◽

Thomas H. Alexander ◽

...

Keyword(s):

Lymph Node ◽

Langerhans Cell Histiocytosis ◽

Cervical Lymph Node ◽

Langerhans Cell ◽

Pulmonary Langerhans Cell Histiocytosis

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Common presentation: Rare disease: Adult Langerhans cell histiocytosis

Tropical Doctor ◽

10.1177/0049475520983644 ◽

2021 ◽

pp. 004947552098364

Author(s):

David Fegan ◽

Mary J Glennon

Keyword(s):

Lymph Node ◽

Lung Disease ◽

Rare Disease ◽

Langerhans Cell Histiocytosis ◽

Lymph Node Biopsy ◽

Langerhans Cell ◽

Common Presentation ◽

Node Biopsy ◽

The Pacific ◽

Granulomatous Lung Disease

A 19-year-old boy presented with signs of a granulomatous lung disease. Sputum testing for tuberculosis was negative. After a year, he returned with generalised lymphadenopathy. Though a clinical diagnosis of tuberculosis was then made and treatment was commenced, a lymph node biopsy revealed Langerhans cell histiocytosis. We are not aware of any other such case described in the Pacific.

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