Common presentation: Rare disease: Adult Langerhans cell histiocytosis

2021 ◽  
pp. 004947552098364
Author(s):  
David Fegan ◽  
Mary J Glennon
Keyword(s):  
Lymph Node ◽  
Lung Disease ◽  
Rare Disease ◽  
Langerhans Cell Histiocytosis ◽  
Lymph Node Biopsy ◽  
Langerhans Cell ◽  
Common Presentation ◽  
Node Biopsy ◽  
The Pacific ◽  
Granulomatous Lung Disease

A 19-year-old boy presented with signs of a granulomatous lung disease. Sputum testing for tuberculosis was negative. After a year, he returned with generalised lymphadenopathy. Though a clinical diagnosis of tuberculosis was then made and treatment was commenced, a lymph node biopsy revealed Langerhans cell histiocytosis. We are not aware of any other such case described in the Pacific.

scholarly journals A Case Report of Nasopharngeal Carcinoma in Children presented with rt. Neck Mass

2015 ◽  
Vol 4 (1) ◽  
pp. 32-35
Author(s):  
AKM Amirul Morshed ◽  
Shahnoor Islam ◽  
Zakia Rahman ◽  
Helena Begum ◽  
Syed Ahsan Ali
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Nasopharyngeal Carcinoma ◽  
Rare Disease ◽  
Neck Mass ◽  
Lymph Node Biopsy ◽  
Standard Protocol ◽  
Neck Swelling ◽  
Standard Chemotherapy ◽  
Node Biopsy

Nasopharyngeal carcinoma is a rare disease in children. It present with mass in the nasopharynx or neck swelling. Recently a six year old boy was diagnosed as a case of NPC and treated with standard chemotherapy. The boy was presented with neck swelling, palatal palsy and ear discharge. The patient was diagnosed by lymph node biopsy and immunohistochemistry. The diagnosis was delayed for 4 months which usually occur in our country. He was diagnosed by lymph node biopsy and immunohistochemistry. He was treated with standard protocol based chemotherapy.J. Paediatr. Surg. Bangladesh 4(1): 32-35, 2013 (January

scholarly journals Langerhans cell histiocytosis (LCH) presenting as pneumothorax and neck lymphadenopathy

2020 ◽  
Vol 5 (1) ◽  
Keyword(s):  
Dendritic Cells ◽  
Lymph Node ◽  
Lung Tissue ◽  
Langerhans Cell Histiocytosis ◽  
Cervical Lymph Node ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Langerhans Cell ◽  
Severe Respiratory Distress ◽  
Lung Cysts

Langerhans Cell Histiocytosis (LCH) is a rare clonal disease characterized by dendritic cells infiltration in various main organs. We report a 6-month-old infant with severe respiratory distress, cervical lymphadenopathy, and reddish skin rashes on face. Diagnostic work up revealed spontaneous pneumothorax on Chest X-ray (CXR). Multiple thin-walled lung cysts and emphysema was discovered on spiral chest CT scan. Lung tissue and cervical lymph node biopsy revealed dendritic cells infiltration. Broncho alveolar lavage (BAL), cervical lymph node and lung tissue biopsy was performed and histopathology was assessed. It was suggestive of LCH with positive immunohistochemistry markers including CD1a, CD68 and S100.

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