Clinical and immunological assessment of 94 patients with primary humoral immunodeficiency: Common variable immunodeficiency, selective IgA deficiency and polysaccharide antibody deficiency syndrome

2015 ◽  
Vol 06 (03) ◽  
pp. 159-166 ◽  
Author(s):  
Maria Gaillard ◽  
Daniela Carelli ◽  
Liliana Bezrodnik
Keyword(s):  
Common Variable Immunodeficiency ◽  
Iga Deficiency ◽  
Deficiency Syndrome ◽  
Antibody Deficiency ◽  
Selective Iga Deficiency ◽  
Humoral Immunodeficiency ◽  
Polysaccharide Antibody ◽  
Antibody Deficiency Syndrome ◽  
Common Variable

Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency

2007 ◽  
Vol 39 (4) ◽  
pp. 430-431 ◽  
Author(s):  
Emanuela Castigli ◽  
Stephen Wilson ◽  
Lilit Garibyan ◽  
Rima Rachid ◽  
Francisco Bonilla ◽  
...  
Keyword(s):  
Common Variable Immunodeficiency ◽  
Iga Deficiency ◽  
Selective Iga Deficiency ◽  
Coding Variants ◽  
Common Variable

scholarly journals Salmonella typhi vaccination response study reveals defective antibody production selective IgA deficiency patient

2015 ◽  
Vol 62 (4) ◽  
pp. 318-322
Author(s):  
Daniel E Pleguezuelo ◽  
Carla Gianelli
Keyword(s):  
Antibody Response ◽  
Antibody Production ◽  
Tetanus Toxoid ◽  
Common Variable Immunodeficiency ◽  
Salmonella Typhi ◽  
Iga Deficiency ◽  
Upper Respiratory Tract ◽  
Selective Iga Deficiency ◽  
Tract Infections ◽  
Common Variable

Selective IgA deficiency (SIgAD) is the most prevalent immunodeficiency worldwide, progressing to common variable immunodeficiency only in few reported cases. We report the case of a Spanish female aged 22 and diagnosed of selective IgA deficiency, a long history of bronchitis, several episodes of pneumonia, bilateral bronchiectasis, normal IgG, IgM, IgG subclasses, and detectable pre-vaccination IgG antibodies against tetanus toxoid and Streptococcus pneumoniae. She was evaluated in our clinic in order to rule out common variable immunodeficiency. We observed good antibody response to tetanus toxoid, absence of circulating switched memory B cells, decreased response to pneumococcal polysaccharide antigens and a lack of response to Salmonella typhi vaccine. Most SIgAD patients presents with upper respiratory tract infections or mild diarrhea. Those with lower tract infections, pneumonia or untreatable diarrhea should follow B-cell subpopulations’ study and antibody response to vaccines. Absence of response to Salmonella typhi vaccine allowed us to expose the defective antibody production.

High frequency of HLA, -A33, -B14, -DR1 in selective IgA deficiency and common variable immunodeficiency

1996 ◽  
Vol 47 (1-2) ◽  
pp. 39
Author(s):  
Despina Chryssovergi ◽  
Helen Pappas ◽  
Katerina Tarassi ◽  
Theophilos Athanasiadis ◽  
Ioanna Economidou ◽  
...  
Keyword(s):  
Common Variable Immunodeficiency ◽  
High Frequency ◽  
Iga Deficiency ◽  
Selective Iga Deficiency ◽  
Common Variable

Primary immunodeficiency

2013 ◽  
pp. 1-80
Author(s):  
Gavin P Spickett
Keyword(s):  
B Lymphocyte ◽  
Iga Deficiency ◽  
Normal Serum ◽  
Antibody Deficiency ◽  
Igg Subclass Deficiency ◽  
Selective Iga Deficiency ◽  
Subclass Deficiency ◽  
Bruton’S Disease ◽  
Common Variable

Introduction Classification of immunodeficiency Clinical features of immunodeficiency Investigation of immunodeficiency Laboratory investigation Major B-lymphocyte disorders Rare antibody deficiency syndromes X-linked agammaglobulinaemia (Bruton’s disease) Common variable immunodeficiency (CVID) CVID 2: complications and treatment Selective IgA deficiency IgG subclass deficiency Specific antibody deficiency with normal serum immunoglobulins...

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