scholarly journals Declining numbers of hepatitis-C-virus-associated liver transplantations in Germany

2021 ◽  
Author(s):  
Heiner Wedemeyer ◽  
Kerstin Herzer ◽  
Yvonne Serfert ◽  
Richard Taubert ◽  
Christian Trautwein ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Transplantations

scholarly journals Replication of Hepatitis C Virus Subgenomes in Nonhepatic Epithelial and Mouse Hepatoma Cells

2003 ◽  
Vol 77 (17) ◽  
pp. 9204-9210 ◽  
Author(s):  
Qing Zhu ◽  
Ju-Tao Guo ◽  
Christoph Seeger
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rna Replication ◽  
Cell Types ◽  
Viral Population ◽  
Mouse Hepatoma ◽  
Liver Transplantations ◽  
Extrahepatic Tissues ◽  
Specific Factors ◽  
Different Cell Types

ABSTRACT The hepatitis C virus (HCV) pandemic affects the health of more than 170 million people and is the major indication for orthotopic liver transplantations. Although the human liver is the primary site for HCV replication, it is not known whether extrahepatic tissues are also infected by the virus and whether nonprimate cells are permissive for RNA replication. Because HCV exists as a quasispecies, it is conceivable that a viral population may include variants that can replicate in different cell types and in other species. We have tested this hypothesis and found that subgenomic HCV RNAs can replicate in mouse hepatoma and nonhepatic human epithelial cells. Replicons isolated from these cell lines carry new mutations that could be involved in the control of tropism of the virus. Our results demonstrated that translation and RNA-directed RNA replication of HCV do not depend on hepatocyte or primate-specific factors. Moreover, our results could open the path for the development of animal models for HCV infection.

Living Donor Liver Transplantations in HIV- and Hepatitis C Virus-Coinfected Hemophiliacs: Experience in a Single Center

2011 ◽  
Vol 91 (11) ◽  
pp. 1261-1264 ◽  
Author(s):  
Kunihisa Tsukada ◽  
Yasuhiko Sugawara ◽  
Junichi Kaneko ◽  
Sumihito Tamura ◽  
Natsuo Tachikawa ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Living Donor ◽  
Single Center ◽  
Donor Liver ◽  
Liver Transplantations

HEPATITIS C VIRUS INFECTION (AND ADDITIONAL NEOPLASMS) AMONG MARGINAL ZONE LYMPHOMAS

1997 ◽  
Vol 96 (2) ◽  
pp. 427-428 ◽  
Author(s):  
FREDERICO SILVESTRI ◽  
GIOVANNI BARILLARI ◽  
RENATO FANIN ◽  
FLAVIA SALMASO ◽  
LAURA INFANTI ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Marginal Zone ◽  
Hepatitis C Virus Infection

Public health challenges in hepatitis C virus infection

2000 ◽  
Vol 15 (5 (Suppl.)) ◽  
pp. E83-E90 ◽  
Author(s):  
John M Kaldor ◽  
Gregory J Dore ◽  
Patricia Kl Correll
Keyword(s):  
Public Health ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Public Health Challenges

Expression of CD81, am ligand for hepatitis C virus (HCV) is increased on CD5+ B-lymphocytes but may not be the receptor for internalisation of HCV

2001 ◽  
Vol 120 (5) ◽  
pp. A552-A552
Author(s):  
M CURRY ◽  
T DEIGNAN ◽  
P COSTELLO ◽  
L GOLDENMASON ◽  
M DUFFY ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
B Lymphocytes

Analysis of interferon signal expression in hepatitis C virus-infected patients' lymphocytes

2001 ◽  
Vol 120 (5) ◽  
pp. A570-A570
Author(s):  
T TANAKA ◽  
K ASAO ◽  
K INOUE ◽  
K KOHARATSUKIYAMA ◽  
M KOHARA
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C

Evolution of hepatitis C virus quasispecies after liver transplantation

2001 ◽  
Vol 120 (5) ◽  
pp. A373-A374
Author(s):  
A LYRA ◽  
X FAN ◽  
S RAMRAKHIANI ◽  
A DIBISCEGLIE
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C
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